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156<br />

SEMMELWEIS UNIVERSITY / FACULTY OF MEDICINE<br />

IMMUNOLOGY<br />

Department of Genetics, Cell and Immunobiology<br />

Course director: Prof. Dr. András Falus<br />

Tutor: A. Kristóf Fülöp, PhD<br />

Subject code: AOKGEN025_1A<br />

Prerequisite subject: Biochemistry, Molecular and Cell Biology III.<br />

Credits: 4<br />

Lectures (2 hr / week) Practices / Seminars (2 hr / week)<br />

1.<br />

The roles, processes, organs and cells of the<br />

immune system<br />

Basic terms, organs and cell of the immune system<br />

2. Principles of natural immunity Methods based on antigen-antibody interactions<br />

3. The complement system Flow cytometry<br />

4.<br />

Acute phase reaction, neuro- and<br />

psychoimmunology<br />

Immunoserology<br />

5. Antigen, antigen presentation and MHCs Cell culturing<br />

6. Antigen receptors and their formation Immunization and vaccination<br />

7.<br />

T lymphocytes and cell-mediated immune<br />

response<br />

Migration of immune cells, homing and extravasation<br />

8. B lymphocytes and humoral immune response Screening methods for autoantibodies, HLA typing<br />

9. Hypersensitivity Midterm test<br />

10. Immunology of transplantation and pregnancy Hypersensitivity I.<br />

11. Natural and pathological autoimmunity Hypersensitivity II.<br />

12.<br />

Immune response in infections,<br />

immunodeficiencies<br />

13. Tumor immunology<br />

14.<br />

Immunopharmacology, immunogenetics and<br />

review<br />

The order of lessons may change.<br />

Biological therapies<br />

Immunological databases, prediction servers,<br />

simulations<br />

Case studies<br />

Attendance of a minimum of 75% of the lessons is necessary for the end-term signature.<br />

Exam: written test in the exam period.<br />

Literature:<br />

Textbook: Falus A. Immunology, Semmelweis PH, 2001.<br />

Hand-out: on www.dgci.sote.hu

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