Invent The Future - UC Davis Health System
Invent The Future - UC Davis Health System
Invent The Future - UC Davis Health System
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TAVI<br />
Trans<br />
femoral<br />
High Risk TF<br />
1:1 Randomization<br />
VS<br />
PARTNER Study Design<br />
ASSESSMENT:<br />
Transfemoral Access<br />
Surgical<br />
AVR<br />
Symptomatic Severe Aortic Stenosis<br />
TAVI<br />
Trans<br />
femoral<br />
ASSESSMENT: High Risk AVR Candidate<br />
3105 Total Patients Screened<br />
High Risk TA<br />
1:1 Randomization<br />
Surgical<br />
AVR<br />
Primary Endpoint: All Cause Mortality<br />
(1 yr) (Non-inferiority)<br />
VS<br />
Total = 1058 patients<br />
n= 700 High Risk 2 Parallel Trials:<br />
Inoperable n=358<br />
Individually Powered<br />
TAVI<br />
Trans<br />
femoral<br />
1:1 Randomization<br />
VS<br />
ASSESSMENT:<br />
Transfemoral Access<br />
Standard<br />
<strong>The</strong>rapy<br />
(usually BAV)<br />
Not In Study<br />
Primary Endpoint: All Cause Mortality<br />
over length of trial (Superiority)