GHS Classification Guidance for the Japanese Government
GHS Classification Guidance for the Japanese Government GHS Classification Guidance for the Japanese Government
No. Test guideline Limit dose 414 Prenatal Development Toxicity Study 1000 mg/kg body weight / day 415 One-Generation Reproduction Toxicity Study 1000 mg/kg body weight 416 Two-Generation Reproduction Toxicity Study 1000 mg/kg body weight / day Reference1.Schardein JL, Chemically Induced Birth Defects-3 rd edition, Marcel Dekker, New York, 2000 Reference2.Shepard TH, Lemire RJ, Catalog of Teratogenic Agents, 11 th edition, Johns Hopkins Univ Press, Boltimore, 2004 168
【GHS 2 nd revised edition】(3.7.5.1) The decision logic which follows is not part of the harmonized classification system but is provided here as additional guidance. It is strongly recommended that the person responsible for classification study the criteria before and during use of the decision logic. 3.7.5.1.1 Decision logic 3.7.1 for substances 169
- Page 122 and 123: possible, and to classify the subst
- Page 124 and 125: and scaling persist to the end of 1
- Page 126 and 127: 【GHS 2 nd revised edition】 Figu
- Page 128 and 129: [Note for the above figure] (a) Cla
- Page 130 and 131: B) Classification criteria in GHS (
- Page 132 and 133: (4)Guidance for classification and
- Page 134 and 135: G) Strategy of testing and evaluati
- Page 136 and 137: 2c Structure activity Skin corrosiv
- Page 138 and 139: done in parallel. This stage should
- Page 140 and 141: criteria given below:” a) If ther
- Page 142 and 143: [Decision Criteria 1]: In the cases
- Page 144 and 145: substance shall be classified in Ca
- Page 146 and 147: The classification is based on any
- Page 148 and 149: 7) Data from various kinds of tests
- Page 150 and 151: Table 3-8 Test data as the basis of
- Page 152 and 153: Category 1B. Mutagens classified a
- Page 154 and 155: c)Exceptionally, strong positive re
- Page 156 and 157: 3-2-6 Carcinogenicity (1)Definition
- Page 158 and 159: The principles of GHS classificatio
- Page 160 and 161: B) Substance for which GHS classifi
- Page 162 and 163: metabolic system, a cautious invest
- Page 164 and 165: hazard warning for pregnant women a
- Page 166 and 167: OECD414 Prenatal development toxici
- Page 168 and 169: D) Decision logic and classificatio
- Page 170 and 171: e considered to be sufficient. (Sub
- Page 174 and 175: 3-2-8 Specific Target Organ Toxicit
- Page 176 and 177: specifically for these effects as d
- Page 178 and 179: existing MSDSs. A literature search
- Page 180 and 181: * Unless a description that definit
- Page 182 and 183: g) When the affected organ can be i
- Page 184 and 185: 3-2-9 Specific Target Organ Toxicit
- Page 186 and 187: Table 3-16: Guidance value ranges f
- Page 188 and 189: (c) Any consistent and significant
- Page 190 and 191: has received some degree of approva
- Page 192 and 193: As for the classification of specif
- Page 194 and 195: formed in the mouth, which then may
- Page 196 and 197: The classification criteria refer t
- Page 198 and 199: 194
- Page 200 and 201: (1)Sources for test data for Hazard
- Page 202 and 203: List 2: Useful information sources
- Page 204 and 205: 3-3)EU classification When classif
- Page 206 and 207: 4-2 Classification of Hazardous to
- Page 208 and 209: water solubility, and which are not
- Page 210 and 211: Tests shall be conducted by using f
- Page 212 and 213: e categorized based on chronic aqua
- Page 214 and 215: endpoint. When it is not clear whet
- Page 216 and 217: that the relevant information sourc
- Page 218 and 219: 214
- Page 220 and 221: R39 Danger of very serious irrevers
【<strong>GHS</strong> 2 nd revised edition】(3.7.5.1)<br />
The decision logic which follows is not part of <strong>the</strong> harmonized classification system but is<br />
provided here as additional guidance. It is strongly recommended that <strong>the</strong> person responsible <strong>for</strong><br />
classification study <strong>the</strong> criteria be<strong>for</strong>e and during use of <strong>the</strong> decision logic.<br />
3.7.5.1.1 Decision logic 3.7.1 <strong>for</strong> substances<br />
169
Change language