GHS Classification Guidance for the Japanese Government

possible” unless the obvious conclusion can be given based on physical properties such as
vapour pressure. The reason why the decision cannot be made shall be clearly described,
for example, “If the test condition is vapour, the substance is determined to fall under
Category ○○, and, if it is mist, it falls under category △△. But it cannot be determined
whether it is vapour or mist based on information obtained, therefore the substance is
determined as “Classification not possible”.
3) Although a substance is mist, its LC50 may be described in ppmV, or for gas, its LC50 may
be described in mg/L. In many assessment documents, LC50 values without test conditions
such as temperature are found. If an accurate conversion is not possible, conversion shall
be performed according to the following formula.
ppmV ≒ mg/L × 1000 × 24.45 / molecular weight(for convertion at 25°C and atmospheric
pressure)
D) Considerations for managing GHS classification criteria newly added by the UN
committee in December 2004
The GHS was largely revised for the following:
Definitions of dust, mist, and vapour were added.
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