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E. Coli

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1. INTRODUCTION<br />

Introduction<br />

Group of Enterobacteriaceae in human includes several that cause<br />

primary infections of the human gastrointestinal tract. Bacteria that<br />

affect the gastrointestinal tract include certain strains of E. coli and<br />

Salmonella, Shigella, and Yersinia entercolitica. Members of this<br />

family are major causes of opportunistic infection (including<br />

septicemia, pneumonia, meningitis and urinary tract infections).<br />

Examples of genera that cause opportunistic infections are:<br />

Citrobacter, Enterobactcr, Escherichia, Hafnia, Morganella,<br />

Providencia and Serratia. Selection of antibiotic therapy is complex<br />

due to the diversity of organisms. The mortality and morbidity are<br />

much higher for the ages less than two years than in older one, fever,<br />

sever loss of electrolyte and dehydration accompanied with watery to<br />

bloody diarrhea (Forfor and Arneil, 1978).<br />

Many species are intestinal pathogens or commensals in the<br />

intestine of man and animal, few are saprophytes in soil and water.<br />

Some species are also transmitted between man and animals (WHO,<br />

2000).<br />

The most common serotypes are E. coli O157:H7 and E. coli<br />

O26:H11. These are unique from the enteropathogenic E. coli (EPEC)<br />

organisms that are the main causes of infantile diarrhea (Shebib et al.,<br />

2003).<br />

Avian pathogenic E.coli (APEC) cause aerosacculitis, poly-<br />

serositis, septicemia in chicken. APEC isolates commonly belong to<br />

1

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