E. Coli

E. Coli E. Coli

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Review of Literature ampicillin, sulphadimidine, trimethoprime sulphadimidine, combination of Kanamycin and gentamycin) on 201 enteropathogenic E. coli isolates. Streptomycin and tetracycline were the least effective but kanamycin and gentamycin were the most effective. The resistance pattern varied between the regions. Blanco et al. (1997) reported that ant microbial therapy is an important tool in reducing the enormous losses in portly industry caused by colibacillosis. Antimicrobial resistance testing of 468 avian E. coli strains isolated in Spain showed very high levels of resistance to trimethoprime-sulfamethoxazole (67%) and the flouroquinolones (13 to 24%). Abd-El-Mawla (1998) applied sensitivity test on 46 E. coli isolates versus to 11 different chemotherapeutic agents. It was noticed that all E.coli isolates were highly sensitive to neomycin, chloramphenicol, genataramycin and amikacin in a descending order of potently 93.6%, 91.3%, 89.1% and 82.6%, respectively. The tested isolates showed high resistance to penicillin G (100%), erythromycin (100%), trimethprime/sulphamethoxazole (80.4%) and flumequine (76.08%). A moderate sensitivity was encountered with tetracycline (73.90%), ampicillin (50%) and streptomycin (39.1%). El-Morsi (1998) found that E. coli showed a high resistance against ampicillin (100%), penicillin (97.67%) and tetracycline (69.77%). Other strains of E. coli showed high sensitivity to norfloxacin (93.02%), enrofloxacin (83.72%) and cefotaxim (72.09%). 20

Review of Literature El-Ghamdi et al. (1999) compared antibiotic resistant E. coli isolates to ampicillin, chloramphenicol, getamicin, spectinomycin, tetracycline and trimethoprime spectinomycin, tetracycline and sulfamethoxazole ranged from 57% to 99.1% Although, amoxicillincluvalanate, ceftazidime And nitro furans ranged from zero to 2.6% resistance to spectonmycin reached 96% multi-drug resistance was alarmingly high. Lambie et al. (2000) isolated E. coli from diseased broilers. The isolates showed an increasing trend of resistance to amoxicillin, paramecia, gentamycin, nitrofurance, norfloxacin and sulphamethoxazole/ trimethoprim overall, norfloxacin appeared as the best antimicrobial drug for treatment. El-Sayed et al. (2001) stated that a high level of multi-resistant strains to the antibiotic. They found that 93.3% of the strains were ampicillin resistant and 73.3% of the strains were to amoxicillin and trimethoprim-sulfamethoxazol. 2.3. Pathogenic Enterbacteria in Human 2.3.1. E. coli Chapman et al. (2002) reported that phage therapy viruses that specifically target pathogenic. Bacteria has been developed over the last 80 years, primarily in the former soviet union, where it was used 21

Review of Literature<br />

ampicillin, sulphadimidine, trimethoprime sulphadimidine, combination<br />

of Kanamycin and gentamycin) on 201 enteropathogenic E.<br />

coli isolates. Streptomycin and tetracycline were the least effective but<br />

kanamycin and gentamycin were the most effective. The resistance<br />

pattern varied between the regions.<br />

Blanco et al. (1997) reported that ant microbial therapy is an<br />

important tool in reducing the enormous losses in portly industry<br />

caused by colibacillosis. Antimicrobial resistance testing of 468 avian<br />

E. coli strains isolated in Spain showed very high levels of resistance<br />

to trimethoprime-sulfamethoxazole (67%) and the flouroquinolones<br />

(13 to 24%).<br />

Abd-El-Mawla (1998) applied sensitivity test on 46 E. coli<br />

isolates versus to 11 different chemotherapeutic agents. It was noticed<br />

that all E.coli isolates were highly sensitive to neomycin, chloramphenicol,<br />

genataramycin and amikacin in a descending order of<br />

potently 93.6%, 91.3%, 89.1% and 82.6%, respectively. The tested<br />

isolates showed high resistance to penicillin G (100%), erythromycin<br />

(100%), trimethprime/sulphamethoxazole (80.4%) and flumequine<br />

(76.08%). A moderate sensitivity was encountered with tetracycline<br />

(73.90%), ampicillin (50%) and streptomycin (39.1%).<br />

El-Morsi (1998) found that E. coli showed a high resistance<br />

against ampicillin (100%), penicillin (97.67%) and tetracycline<br />

(69.77%). Other strains of E. coli showed high sensitivity to norfloxacin<br />

(93.02%), enrofloxacin (83.72%) and cefotaxim (72.09%).<br />

20

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