The Contribution of cocoa additive to cigarette smoking addiction

Page 47 of 207 RIVM report 650270002
Serotonin
3.3 Serotonin
GENERAL
IUPAC systemic name: 3-(2-Aminoethyl)-1H-indol-5-ol (1).
Synonyms: 3-(2-Aminoethyl)-1H-indol-5-ol; 5-hydroxytryptamine; 3-(.beta.aminoethyl)-5-hydroxyindole;
5-hydroxy-3-(.beta.-aminoethyl)indole; enteramine;
thrombocytin; thrombotonin (2).
Molecular formula: C10H12N2O (1, 2).
Molecular structure
H
N
HO
NH 2
Molecular weight: 176.22 g/mol (1).
Alifatic: 2 C-atoms (1).
Aromatic: yes, indol structure (1).
N containing: Yes (1).
Halogen containing:No; the commercial serotonin compound is the hydrochloric salt
(2) .
CAS registry no.: 50-67-9 (2).
Storage: Hydrochloride serotonin, C10H12N2O.HCl is a hygroscopic crystal and is
sensitive to light (2). Therefore this compound should be stored in an airtight
container and protected from light.
R/S classification: for the HCl salt: R: 20/21/22,36/37/38,40, S: 26,36,22 (1).
dangercode (transport): No data available
Properties:
melting point: 167.5 ºC (1).
boiling point: no data available
density: no data available
refractive index: no data available
solubility: in water : 20 g/l (1).
substance description:
color: no data available
liquid/gas/powder: powder (1).
odor/taste: no data available
volatility: no data available
pKa: pK1' = 4.9; pK2' = 9.8 (2).
PA: kcal/mol: no data available
flammability: no data available
FP = no data available
FL Limits = no data available
IT = no data available
decomposition temperature: no data available