The Contribution of cocoa additive to cigarette smoking addiction
The Contribution of cocoa additive to cigarette smoking addiction
The Contribution of cocoa additive to cigarette smoking addiction
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Page 125 <strong>of</strong> 207 RIVM report 650270002<br />
Tyramine<br />
3.7 Tyramine<br />
GENERAL<br />
IUPAC systematic name: tyramine (is a trivial name) (1)<br />
Synonyms: 4-(2-aminoethyl)phenol; 4-hydroxyphenethylamine; p-betaaminoethylphenol;<br />
alpha-(4-hydroxyphenol)-beta-aminoethane (1)<br />
Molecular formula: C8H11NO (1)<br />
Molecular structure<br />
Molecular weight: 137.18 g/mol (1)<br />
Alifatic: Ethylamine group (1)<br />
Aromatic: Phenol group (1)<br />
N containing: primary amine (1)<br />
Halogen containing: no<br />
CAS registry no.: 51-67-2 (1)<br />
S<strong>to</strong>rage:<br />
R/S classification: R36/37/38; S26/36 (2)<br />
dangercode (transport): no data available.<br />
Properties:<br />
melting point: 161ºC (1)<br />
boilingpoint: 175 – 181 ºC at 1067 Pa (1), 205 – 207 ºC at 3333 Pa (3)<br />
solubility: water: 10 g/l at 15 ºC; soluble in organic solvent(s): benzene, ethanol<br />
(4)<br />
density: no data available<br />
refractive index: no data available<br />
substance description:<br />
color: colourless (2)<br />
liquid/gas/powder: crystalline solid (2)<br />
odor/taste: no data available<br />
volatility: no data available<br />
pKa: pKa1 is 9.74 and pKa2 is10.52 (3)<br />
PA: no data available<br />
Flammability: no data available<br />
FP =<br />
FL Limits =<br />
IT =<br />
decomposition temperature: no data available<br />
stability: a 12.66 mg tyramine hydrochloride water solution (eqivalent <strong>to</strong> 10 mg<br />
tyramine base) is stable for at least 1 year s<strong>to</strong>red in dark bottle at 4 ºC (5).<br />
vapour pressure/ vapour tension (20 °C): no data available<br />
vapour pressure (50 °C): no data available<br />
relative density: no data available<br />
octanol water partition coefficient, log P, log KOW: log KOW is 0.72 (4)
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