Occupational Intakes of Radionuclides Part 1 - ICRP
Occupational Intakes of Radionuclides Part 1 - ICRP
Occupational Intakes of Radionuclides Part 1 - ICRP
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DRAFT REPORT FOR CONSULTATION<br />
Figure 19. Model structure applied in the Publication 72 series to calcium, strontium, barium,<br />
lead, radium, and uranium. This structure (or modest variations <strong>of</strong> it) are applied to a number<br />
<strong>of</strong> elements in this report series, including elements not regarded as bone-seekers.<br />
Abbreviations: Exch = exchangeable, Nonexch = nonexchangeable, RBC = red blood cells.<br />
(216) The systemic models used in the Publication 72 series were applied in<br />
Publication 68 (<strong>ICRP</strong>, 1994b), along with <strong>ICRP</strong>’s Human Respiratory Tract Model<br />
(<strong>ICRP</strong>, 1994a), to update dose coefficients for occupational intake <strong>of</strong> radionuclides<br />
based on recommendations in Publication 60 (<strong>ICRP</strong>, 1991). For elements not<br />
addressed in the Publication 72 series, the systemic biokinetic models applied in<br />
Publication 68 were taken from Publication 30 and modified to include specific<br />
excretion pathways to address doses to the urinary bladder and colon.<br />
(217) The biokinetic models applied in Publication 68 were used in Publication 78<br />
(<strong>ICRP</strong>, 1997) to provide new recommendations concerning interpretation <strong>of</strong> bioassay<br />
data for workers for selected radioisotopes <strong>of</strong> 15 elements. The systemic models for<br />
nine <strong>of</strong> the 15 elements addressed in Publication 78 were physiological based models<br />
adopted in the Publication 72 series.<br />
3.5.3 Systemic model structures used in this report series<br />
(218) It is now generally recognised that the physiologically descriptive model<br />
structures introduced for selected elements in the Publication 72 series have a number<br />
<strong>of</strong> potential advantages over the retention-function models traditionally used in<br />
radiation protection. For example, a physiological descriptive model structure<br />
facilitates the use <strong>of</strong> physiological information and physiologically reasonable<br />
assumptions as a supplement to radiobiological data in the development <strong>of</strong> model<br />
parameter values; provides a basis for extrapolating beyond the radiobiological<br />
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