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Occupational Intakes of Radionuclides Part 1 - ICRP

Occupational Intakes of Radionuclides Part 1 - ICRP

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DRAFT REPORT FOR CONSULTATION<br />

Bone marrow. See also ‘Active (bone) marrow’; ‘Inactive (bone) marrow’.<br />

Bone marrow is a s<strong>of</strong>t, highly cellular tissue that occupies the cylindrical<br />

cavities <strong>of</strong> long bones and the cavities defined by the bone trabeculae <strong>of</strong> the<br />

axial and appendicular skeleton. Total bone marrow consists <strong>of</strong> a sponge-like,<br />

reticular, connective tissue framework called stroma, myeloid (blood-cellforming)<br />

tissue, fat cells (adipocytes), small accumulations <strong>of</strong> lymphatic<br />

tissue, and numerous blood vessels and sinusoids. There are two types <strong>of</strong> bone<br />

marrow, red (active) and yellow (inactive).<br />

Committed Effective Dose (E(50)). See also ‘Effective Dose’.<br />

In this report series: effective dose calculated with the use <strong>of</strong> committed<br />

equivalent doses.<br />

E(<br />

50)<br />

Male<br />

Female<br />

H ( r <br />

<br />

T , 50)<br />

H(<br />

rT<br />

, 50)<br />

wT<br />

<br />

<br />

<br />

2<br />

<br />

T<br />

Committed Equivalent Dose (H (rT50)). See also ‘Equivalent Dose’.<br />

In this report series: Equivalent dose calculated using a 50-year commitment<br />

period. It is the time integral <strong>of</strong> the equivalent dose rate in a tissue or organ rT<br />

<strong>of</strong> the Reference Adult Male or the Reference Adult Female that is predicted<br />

by the reference biokinetic and dosimetric models following intake <strong>of</strong><br />

radioactive material into the body <strong>of</strong> the Reference Worker. The integration<br />

period is 50 years following the intake.<br />

50<br />

( r , 50)<br />

H<br />

( r , t)<br />

dt<br />

<br />

H T<br />

T<br />

0<br />

For both sexes the equivalent dose rate H ( rT<br />

, t)<br />

in target tissue rT at time t<br />

after an acute intake is expressed as<br />

<br />

H ( r , t)<br />

A(<br />

r , t)<br />

S ( r r )<br />

T<br />

r<br />

S<br />

S<br />

w<br />

T<br />

S<br />

where:<br />

A(rS,t) is the activity <strong>of</strong> the radionuclide in source region rS at time t<br />

after intake, Bq, predicted by the reference biokinetic models for Reference<br />

Worker,<br />

Sw(rS←rT) is the radiation-weighted S value (Bolch et al, 2009); i.e. the<br />

equivalent dose in target tissue rT per nuclear transformation in source region<br />

rS, Sv (Bq s) -1 , for the Reference Adult Male and Reference Adult Female.<br />

Derived Air Concentration (DAC)<br />

The DAC is the activity concentration in air in Bq/m 3 <strong>of</strong> the radionuclide<br />

considered which would lead to an intake <strong>of</strong> an ALI assuming a breathing rate<br />

9

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