Occupational Intakes of Radionuclides Part 1 - ICRP

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Extrathoraci
c
Thoracic
(lungs)
ET1 (anterior
nose)
ET2 (posterior
nose, larynx,
pharynx)
BB (bronchial) Secretory
(BBsec)
Basal
bb
(bronchiolar)
AI (alveolarinterstitial)
DRAFT REPORT FOR CONSULTATION
Male Female
Basal 40-50 2.000 x 10 -5 1.729 x
78
10 -5
Basal 40-50 4.500 x 10 -4 3.890 x
10 -4
(BBbas)
10-40
35-50
8.648 x 10 -4
4.324 x 10 -4
7.771 x
10 -4
3.885 x
10 -4
Secretory 4-12 1.949 x 10 -3 1.874 x
10 -3
0.001
0.999
1/3 c
1/3
d 1.100 0.904 1/3
a
Reference values (see footnote a to Table 3). For the BB, bb and AI regions each
value of Ai is exactly one-third.
b
Male values were taken from Publication 68, Table 3 (ICRP, 1994b). Female values
for ET and AI were taken from Publication 66, Table 5. Female values for BB were
calculated here using information from Publication 66, Tables 2, 4 and B6 (ICRP, 1994a).
Masses for BBsec and BBbas are the masses of bronchial epithelium through which the nuclei
of secretory cells and basal cells respectively are distributed and are based on reference
values of airway dimensions. The mass of AI includes blood, but excludes lymph nodes.
c
The dose to BB (HBB) is calculated as the arithmetic mean of the doses to BBsec and
BBbas.
d Average dose to region calculated.
3.3 Human Alimentary Tract Model (HATM)
(175) The Publication 30 (ICRP, 1979) model of the gastrointestinal tract has been
replaced by the Human Alimentary Tract Model (HATM) described in Publication
100 (ICRP, 2006). This replacement was motivated by a number of developments,
including the availability of improved information on the gut transit of materials, and
developments in our understanding of the location of sensitive cells. The model
structure is shown in Figure 13, and parameter values are shown in Table 9. As for the
HRTM, an important feature of the HATM is the specific calculation of doses to
target regions containing sensitive cells for cancer induction, and the consideration of
specific absorption and/or retention values, where information is available. The
HATM and the HRTM are compatible and inter-connected, as shown in Figure 13.
3.3.1 Structure
(176) The HATM depicts the entry of a radionuclide into the oral cavity by
ingestion or into the oesophagus after particle transport from the respiratory tract. It
describes the sequential transfer through all alimentary tract regions, including the
oral cavity, oesophagus, stomach, small intestine, and segments of the colon, followed