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Occupational Intakes of Radionuclides Part 1 - ICRP

Occupational Intakes of Radionuclides Part 1 - ICRP

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DRAFT REPORT FOR CONSULTATION<br />

other material deposited in BB and ET2 is cleared to the alimentary<br />

tract by particle transport.<br />

Type M: 20% absorbed with a half-time <strong>of</strong> ~6 hours and 80% with a half-time<br />

<strong>of</strong> ~140 d. There is rapid absorption <strong>of</strong> ~20%, 5% and 0.5% <strong>of</strong> material<br />

deposited in bb, BB and ET2, respectively. About 80% <strong>of</strong> the deposit in<br />

AI eventually reaches body fluids.<br />

Type S: 1% absorbed with a half-time <strong>of</strong> ~6 hours and 99% with a half-time <strong>of</strong><br />

~7000 d. There is rapid absorption <strong>of</strong> ~1%, 0.25% and 0.03% <strong>of</strong><br />

material deposited in bb, BB and ET2, respectively. About 30% <strong>of</strong> the<br />

deposit in AI eventually reaches body fluids.<br />

(156) For absorption Types F, M, and S, some the material deposited in ET1 is<br />

removed by extrinsic means. Most <strong>of</strong> the material deposited in the respiratory tract<br />

that is not absorbed is cleared to the alimentary tract by particle transport. The small<br />

amounts transferred to lymph nodes continue to be absorbed into body fluids at the<br />

same rate as in the respiratory tract.<br />

Decay products formed in the respiratory tract<br />

(157) Note that the following applies specifically to decay products formed in the<br />

respiratory tract after inhalation <strong>of</strong> the parent radionuclide. Decay products formed<br />

before inhalation and inhaled with the parent are generally treated as separate intakes,<br />

and so each decay product is assumed to adopt the biokinetics appropriate to the<br />

element <strong>of</strong> which it is an isotope. Many issues relating to the behaviour <strong>of</strong> decay<br />

products in the respiratory tract arise in connection with the natural decay series,<br />

which are therefore shown in Figures 10 (uranium-238 series), 11 (uranium-235<br />

series) and 12 (thorium-232 series).<br />

(158) Publication 66 (<strong>ICRP</strong>, 1994a, Paragraph 272) noted that it would be expected<br />

that:<br />

the rate at which a particle dissociates is determined by the particle matrix and<br />

therefore the dissolution parameter values <strong>of</strong> the inhaled material would be<br />

applied to decay products formed within particles in the respiratory tract<br />

('shared kinetics');<br />

decay products formed as noble gases, including radon, would be exceptions<br />

because they would diffuse from the particles;<br />

the behaviour <strong>of</strong> dissociated material would depend on its elemental form, and<br />

so, for example, bound fraction parameter values for a decay product would<br />

not be those <strong>of</strong> the parent ('independent kinetics').<br />

(159) These points are considered in turn below. However, it should be noted that in<br />

previous applications <strong>of</strong> the HRTM (e.g. Publications 68, 71, 72 and 78), with the<br />

exception <strong>of</strong> noble gases, the absorption parameters <strong>of</strong> the parent were applied to all<br />

members <strong>of</strong> the decay chain formed in the respiratory tract (shared kinetics). After<br />

consideration (see below) the same approach is taken in this series <strong>of</strong> documents.<br />

Retention in the particle matrix<br />

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