Occupational Intakes of Radionuclides Part 1 - ICRP
Occupational Intakes of Radionuclides Part 1 - ICRP
Occupational Intakes of Radionuclides Part 1 - ICRP
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DRAFT REPORT FOR CONSULTATION<br />
other material deposited in BB and ET2 is cleared to the alimentary<br />
tract by particle transport.<br />
Type M: 20% absorbed with a half-time <strong>of</strong> ~6 hours and 80% with a half-time<br />
<strong>of</strong> ~140 d. There is rapid absorption <strong>of</strong> ~20%, 5% and 0.5% <strong>of</strong> material<br />
deposited in bb, BB and ET2, respectively. About 80% <strong>of</strong> the deposit in<br />
AI eventually reaches body fluids.<br />
Type S: 1% absorbed with a half-time <strong>of</strong> ~6 hours and 99% with a half-time <strong>of</strong><br />
~7000 d. There is rapid absorption <strong>of</strong> ~1%, 0.25% and 0.03% <strong>of</strong><br />
material deposited in bb, BB and ET2, respectively. About 30% <strong>of</strong> the<br />
deposit in AI eventually reaches body fluids.<br />
(156) For absorption Types F, M, and S, some the material deposited in ET1 is<br />
removed by extrinsic means. Most <strong>of</strong> the material deposited in the respiratory tract<br />
that is not absorbed is cleared to the alimentary tract by particle transport. The small<br />
amounts transferred to lymph nodes continue to be absorbed into body fluids at the<br />
same rate as in the respiratory tract.<br />
Decay products formed in the respiratory tract<br />
(157) Note that the following applies specifically to decay products formed in the<br />
respiratory tract after inhalation <strong>of</strong> the parent radionuclide. Decay products formed<br />
before inhalation and inhaled with the parent are generally treated as separate intakes,<br />
and so each decay product is assumed to adopt the biokinetics appropriate to the<br />
element <strong>of</strong> which it is an isotope. Many issues relating to the behaviour <strong>of</strong> decay<br />
products in the respiratory tract arise in connection with the natural decay series,<br />
which are therefore shown in Figures 10 (uranium-238 series), 11 (uranium-235<br />
series) and 12 (thorium-232 series).<br />
(158) Publication 66 (<strong>ICRP</strong>, 1994a, Paragraph 272) noted that it would be expected<br />
that:<br />
the rate at which a particle dissociates is determined by the particle matrix and<br />
therefore the dissolution parameter values <strong>of</strong> the inhaled material would be<br />
applied to decay products formed within particles in the respiratory tract<br />
('shared kinetics');<br />
decay products formed as noble gases, including radon, would be exceptions<br />
because they would diffuse from the particles;<br />
the behaviour <strong>of</strong> dissociated material would depend on its elemental form, and<br />
so, for example, bound fraction parameter values for a decay product would<br />
not be those <strong>of</strong> the parent ('independent kinetics').<br />
(159) These points are considered in turn below. However, it should be noted that in<br />
previous applications <strong>of</strong> the HRTM (e.g. Publications 68, 71, 72 and 78), with the<br />
exception <strong>of</strong> noble gases, the absorption parameters <strong>of</strong> the parent were applied to all<br />
members <strong>of</strong> the decay chain formed in the respiratory tract (shared kinetics). After<br />
consideration (see below) the same approach is taken in this series <strong>of</strong> documents.<br />
Retention in the particle matrix<br />
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