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Occupational Intakes of Radionuclides Part 1 - ICRP

Occupational Intakes of Radionuclides Part 1 - ICRP

Occupational Intakes of Radionuclides Part 1 - ICRP

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DRAFT REPORT FOR CONSULTATION<br />

(diffusion) processes acting competitively. Regional deposition fractions were<br />

calculated for aerosols having lognormal particle size distributions, with geometric<br />

standard deviations taken to be a function <strong>of</strong> the median particle diameter, increasing<br />

from a value <strong>of</strong> 1.0 at 0.6 nm to a value <strong>of</strong> 2.5 above about 1 μm.<br />

(94) No changes are made here to the Publication 66 implementation <strong>of</strong> the<br />

deposition model for aerosols, except for the distribution <strong>of</strong> the deposit in the ET<br />

airways between regions ET1 and ET2. In Publication 66 (<strong>ICRP</strong>, 1994a) it was<br />

assessed, on the basis <strong>of</strong> the available information, that deposition in ET1 is somewhat<br />

higher than in ET2 during inhalation through the nose, and that most <strong>of</strong> the particles<br />

deposited in ET1 are cleared by nose-blowing, but some clear to ET2 and hence to the<br />

alimentary tract on a time scale <strong>of</strong> hours. However, because <strong>of</strong> the lack <strong>of</strong> quantitative<br />

information, these judgements were applied in a simplified form in the original<br />

HRTM. It was assumed that particles deposited in the nasal passage during inhalation<br />

are partitioned equally between ET1 and the posterior nasal passage, which is part <strong>of</strong><br />

ET2. (However, because <strong>of</strong> the way the deposition efficiencies were calculated for<br />

polydisperse aerosols during inhalation and exhalation, for most aerosol sizes <strong>of</strong><br />

interest in radiation protection the deposition fractions given in Publication 66 are<br />

somewhat higher for ET2 than for ET1.) As described in the section below on particle<br />

transport from the ET airways, recent experimental studies (Smith et al, 2011) enable<br />

a more accurate representation <strong>of</strong> ET deposition and clearance to be implemented<br />

here. Results for a group <strong>of</strong> subjects indicated that the distribution <strong>of</strong> the deposit in<br />

the ET airways can be characterised by mean deposition fractions <strong>of</strong> 65% to ET1 and<br />

35% to ET2. To calculate the fractions <strong>of</strong> inhaled material deposited in ET1 and ET2,<br />

the fractions deposited in ET1 and ET2 (calculated using the original HRTM) were<br />

summed to give the total deposit in the ET airways, and then re-partitioned 65% to<br />

ET1 and 35% to ET2. (For mouth breathing there is no deposition in ET1 and the<br />

fraction deposited in ET2 remains as calculated using the original HRTM.)<br />

(95) For inhalation <strong>of</strong> radionuclides by workers, the reference subjects are taken to<br />

be normal nose-breathing adult males and females at light work. However, for<br />

simplicity, deposition in (and clearance from) the respiratory tract are calculated for<br />

the reference adult male only. For occupational exposure, the default value<br />

recommended for the Activity Median Aerodynamic Diameter (AMAD) is 5 μm<br />

(<strong>ICRP</strong>, 1994b), consistent with the review <strong>of</strong> data by Dorrian and Bailey (1995) and<br />

Ansoborlo et al (1997). Fractional deposition in each region <strong>of</strong> the respiratory tract <strong>of</strong><br />

the reference worker is given in Table 3 for aerosols <strong>of</strong> 5 μm AMAD.<br />

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