Occupational Intakes of Radionuclides Part 1 - ICRP
Occupational Intakes of Radionuclides Part 1 - ICRP
Occupational Intakes of Radionuclides Part 1 - ICRP
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DRAFT REPORT FOR CONSULTATION<br />
Type S deposited materials that are relatively insoluble in the<br />
respiratory tract. (Slow absorption.)<br />
Type V deposited materials that, for dosimetric purposes, are<br />
assumed to be instantaneously absorbed into body fluids from the respiratory<br />
tract: only certain gases and vapours. (Very fast absorption)<br />
Uptake. See also ‘Intake’<br />
Activity that enters body fluids from the respiratory or alimentary tract or<br />
through the skin.<br />
Terms for Bioassay Interpretation<br />
Action level<br />
A pre-set level above which some remedial action should be considered.<br />
Activity<br />
The number <strong>of</strong> nuclear transformations per unit time (s) <strong>of</strong> a radioactive<br />
material. The SI unit <strong>of</strong> the activity is the becquerel (Bq): 1 Bq = 1 s -1<br />
Bioassay<br />
Any procedure used to determine the nature, activity, location or retention <strong>of</strong><br />
radionuclides in the body by direct (in vivo) measurement or by indirect (in<br />
vitro) analysis <strong>of</strong> material excreted or otherwise removed from the body.<br />
Bioassay function<br />
In this report series: A set <strong>of</strong> tabulated values m(t) predicted by the reference<br />
biokinetic models describing the time course <strong>of</strong> the activity in the body<br />
(“retention function”) or the activity excreted via urine or faeces (“excretion<br />
function”) following a single intake at time t = 0. In general, the retention<br />
functions represent the body or organ activity at the time t after the intake,<br />
whereas the excretion functions represent the daily excretion: the integral <strong>of</strong><br />
the instantaneous excretion rate from (t – 1) until t, where t is the number <strong>of</strong><br />
days after a single intake (integer).<br />
Decision Threshold<br />
Fixed value <strong>of</strong> a measured quantity that, when exceeded by the result <strong>of</strong> an<br />
actual measurement quantifying a physical effect (e.g. the presence <strong>of</strong> a<br />
radionuclide in a sample), may be taken to indicate that the physical effect is<br />
present. The decision threshold is the critical value <strong>of</strong> a statistical test for the<br />
decision between the hypothesis that the physical effect is not present and the<br />
alternative hypothesis that it is present. When the critical value is exceeded by<br />
the result <strong>of</strong> an actual measurement, this is taken to indicate that the<br />
hypothesis should be rejected. The statistical test is designed in such a way<br />
that the probability <strong>of</strong> wrongly rejecting the hypothesis (Type I error) is at<br />
most equal to a given value, α. The decision threshold is an a posteriori<br />
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