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Occupational Intakes of Radionuclides Part 1 - ICRP

Occupational Intakes of Radionuclides Part 1 - ICRP

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DRAFT REPORT FOR CONSULTATION<br />

bbseq long-term retention (t½ about 700 d) in airway walls <strong>of</strong> a small fraction<br />

<strong>of</strong> the particles deposited in the bronchiolar region.<br />

ALV retention (t½ about 200 d) <strong>of</strong> particles deposited in the alveoli. A<br />

fraction (0.67) <strong>of</strong> the deposit is removed by particle transport to the ciliated<br />

airways (bb′), while the remainder penetrates to the interstitium (INT).<br />

INT very long-term retention (t½ about 60 y) <strong>of</strong> the particles deposited in<br />

the alveoli that penetrate to the interstitium: the particles are removed slowly<br />

to the lymph nodes.<br />

Deposition<br />

Refers to the initial processes determining how much <strong>of</strong> the material in the<br />

inspired air remains behind in the respiratory tract after exhalation. Deposition<br />

<strong>of</strong> material occurs during both inspiration and exhalation.<br />

Endogenous excretion<br />

Term used to specify the excretion <strong>of</strong> materials from body fluids to the<br />

alimentary tract, applying to biliary excretion and passage <strong>of</strong> materials through<br />

the alimentary tract wall.<br />

Endosteum (or endosteal layer)<br />

A 50 µm-thick layer covering the surfaces <strong>of</strong> the bone trabeculae in regions <strong>of</strong><br />

trabecular spongiosa and those <strong>of</strong> the cortical surfaces <strong>of</strong> the medullary<br />

cavities within the shafts <strong>of</strong> all long bones. It is assumed to be the target tissue<br />

for radiogenic bone cancer. This target region replaces that previously<br />

introduced in <strong>ICRP</strong> Publications 26 and 30 (<strong>ICRP</strong>, 1977, 1979) – the bone<br />

surfaces – which had been defined as a single-cell layer, 10 µm in thickness,<br />

covering the surfaces <strong>of</strong> both the bone trabeculae and the Haversian canals <strong>of</strong><br />

cortical bone.<br />

Exogenous excretion<br />

Term used to specify the (faecal) excretion <strong>of</strong> material that passes through the<br />

alimentary tract without absorption.<br />

Extrathoracic (ET) Airways<br />

<strong>Part</strong> <strong>of</strong> the respiratory tract, consisting <strong>of</strong> the anterior nose (the ET1 region)<br />

and the posterior nasal passages, pharynx and larynx (the ET2 region). Note<br />

that the oral part <strong>of</strong> the pharynx is no longer part <strong>of</strong> ET2 because it is included<br />

in the HATM.<br />

Exposure (in the context <strong>of</strong> inhalation)<br />

The product <strong>of</strong> the air concentration <strong>of</strong> a radionuclide to which a person is<br />

exposed (Bq m -3 ) and the time <strong>of</strong> exposure. More generally, when the air<br />

concentration varies with time, the time integral <strong>of</strong> the air concentration <strong>of</strong> a<br />

radionuclide to which a person is exposed, integrated over the time <strong>of</strong><br />

exposure.<br />

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