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Occupational Intakes of Radionuclides Part 1 - ICRP

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DRAFT REPORT FOR CONSULTATION<br />

E(50) = I x e(50) = M x e(50)/m(t)…………(7.2)<br />

If the time <strong>of</strong> the intake during a monitoring period is unknown, the intake is<br />

generally assumed to have occurred at the mid-point <strong>of</strong> the period (Section 6.3).<br />

(412) Dose per unit content, z(t), represents the committed effective dose per unit<br />

organ (body) radionuclide content or per unit radionuclide content in the 24 hour<br />

excreta sample at time t after an acute intake. The use <strong>of</strong> z(t) simplifies the dose<br />

evaluation to a single step, instead <strong>of</strong> the traditional method <strong>of</strong> first applying the<br />

retention or excretion function m(t) to calculate the intake (equation 7.1), and then the<br />

dose coefficient e(50) to calculate the resulting effective dose (equation 7.2).<br />

E(50) = M x z(t) ………………………(7.3)<br />

(413) Values <strong>of</strong> dose per unit content, z(t), are provided to allow a more<br />

straightforward assessment <strong>of</strong> committed dose from bioassay measurements without<br />

the need to first determine the intake. For measurements <strong>of</strong> activity in body tissues<br />

and excreta, predicted values <strong>of</strong> committed effective dose are tabulated for various<br />

times after radionuclide intake following inhalation, ingestion, entry through wounds<br />

or uptake to blood.<br />

(414) Graphs <strong>of</strong> predicted activity <strong>of</strong> the radionuclide in selected body tissues, urine<br />

(daily excretion) and faeces (daily excretion), at various times after intake, are given<br />

for an acute intake <strong>of</strong> 1 Bq <strong>of</strong> the radionuclide (unit intake). These values correspond<br />

to m(t). Figures are given for intakes by inhalation, ingestion, and direct transfer to<br />

blood. Data are given in the form <strong>of</strong> fractional activity related to the intake, i.e. Bq per<br />

Bq intake for retention and daily excretion. One exception to this is for intake <strong>of</strong><br />

tritiated water where data are given in Bq l -1 per Bq intake since this is directly related<br />

to the dose rate.<br />

(415) Data are given for time periods up to 10 4 days after intake or until the<br />

fractional activity is less than 10 -10 <strong>of</strong> the intake.<br />

(416) For each radionuclide, the monitoring periods have been selected (as in<br />

Publication 78, paragraph 91) for intake by inhalation for all absorption Types so that<br />

any underestimation introduced by an unknown time <strong>of</strong> intake is no more than a factor<br />

<strong>of</strong> three when an acute intake in the middle <strong>of</strong> the monitoring interval is assumed. The<br />

frequency <strong>of</strong> monitoring, determined using the models that have been applied, is<br />

determined both by the behaviour <strong>of</strong> the radionuclide in the body and its physical<br />

half-life. Within any workplace, the probability <strong>of</strong> occurrence <strong>of</strong> an intake should also<br />

be taken into account.<br />

(417) The accompanying CD-ROM gives extensive additional information for all<br />

relevant isotopes <strong>of</strong> each element, including:<br />

Committed effective dose (Sv) per unit measurement (Bq) for an acute intake<br />

by inhalation <strong>of</strong> aerosols with median sizes ranging from an AMTD <strong>of</strong> 0.001<br />

µm to an AMAD <strong>of</strong> 20 µm;<br />

Committed effective dose (Sv) per unit measurement (Bq) for an acute intake<br />

by ingestion, with default fA values appropriate for the element;<br />

Bioassay data (i.e. whole body and/or organ retention, and daily urinary and<br />

faecal excretion, Bq per Bq intake), for an acute intake by inhalation <strong>of</strong><br />

aerosols with median sizes ranging from an AMTD <strong>of</strong> 0.001 µm to an AMAD<br />

138

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