Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
VERAPAMIL Trade names: APO-Verap; Arpamyl LP; Azupamil; Berkatens; Calan (Pfizer); Chronovera; Cordilox; Covera-HS (Pfizer); Geangin; Isoptin (Abbott); Isoptine; Nu-Verap; Tarka (Abbott); Veraken; Verelan (Schwarz) Indications: Angina, hypertension Category: Antiarrhythmic class IV; Calcium channel blocker Half-life: 2–8 hours Clinically important, potentially hazardous interactions with: acebutolol, amiodarone, aspirin, atenolol, atorvastatin, betaxolol, carbamazepine, carteolol, clonidine, dantrolene, digoxin, dofetilide, epirubicin, eplerenone, erythromycin, esmolol, eucalyptus, lovastatin, metoprolol, mistletoe, nadolol, penbutolol, pindolol, propranolol, quinidine, ranolazine, sibutramine, simvastatin, timolol Tarka is trandolapril and verapamil Reactions Skin Acne (1989): Stern R+, Arch Intern Med 149, 829 Acute febrile neutrophilic dermatosis (Sweet’s syndrome) (1998): Knowles S+, JAmAcadDermatol38, 201 (passim) Angioedema (1998): Knowles S+, JAmAcadDermatol38, 201 (passim) (1989): Sadick NS+, JAmAcadDermatol21, 132 (1989): Stern R+, Arch Intern Med 149, 829 Dermatitis Diaphoresis (
574 VERAPAMIL (2005): Cock JM, Manizales, Colombia (unilateral) (from Internet) (observation) Other Cough (2003): Guay DR, Clin Ther 25(3), 713 Erythromelalgia (1992): Drenth JP+, Br J Dermatol 127, 292 Gynecomastia (
- Page 598 and 599: (2000): Ernst E+, Forsch Komplement
- Page 600 and 601: Reactions Skin Allergic reactions (
- Page 602 and 603: Reactions Skin Diaphoresis (>1%) Ed
- Page 604 and 605: Mucosal Oral ulceration (1987): Hig
- Page 606 and 607: TETRACYCLINE Trade names: Apo-Tetra
- Page 608 and 609: Xerosis (2002): Bariol C+, J Gastro
- Page 610 and 611: Eyes Conjunctivitis (allergic conta
- Page 612 and 613: Other Anaphylactoid reactions/Anaph
- Page 614 and 615: (2000): Chemnitz JM+, Med Klin (Ger
- Page 616 and 617: Note: Cutaneous side-effects of bet
- Page 618 and 619: Other Cough (0.8%) Fever (4.6%) Hep
- Page 620 and 621: TOLAZAMIDE* Trade names: Diabewas;
- Page 622 and 623: Reactions Skin Erythema (1.9%) Fung
- Page 624 and 625: TOSITUMOMAB & IODINE 131 Trade name
- Page 626 and 627: (2001): Vogel CL+, Oncology 61, 37
- Page 628 and 629: (1997): Gilchrest BA, JAmAcadDermat
- Page 630 and 631: Erythema (1999): Alexiou C+, Laryng
- Page 632 and 633: *Note: Trichlormethiazide is a sulf
- Page 634 and 635: TRIMETHOPRIM* Trade names: Abaprim;
- Page 636 and 637: Myalgia/Myositis/Myopathy/Myotoxici
- Page 638 and 639: Other Death (2002): Avarello TP+, N
- Page 640 and 641: (2001): Pechlaner C+, Blood Coagul
- Page 642 and 643: Bullous dermatitis (2001): Christ E
- Page 644 and 645: (1985): Schifter S+, Lancet 2, 499
- Page 646 and 647: Reactions Skin Allergic reactions (
- Page 650 and 651: Mucosal Gingival hyperplasia/hypert
- Page 652 and 653: (2001): Laack E+, Ann Oncol 12(12),
- Page 654 and 655: Fixed eruption (
- Page 656 and 657: (1986): Sjoberg A+, Lakartidningen
- Page 658 and 659: (1990): Broder S+, Am J Med 88, 31S
- Page 660 and 661: (1989): Valencia ME+, Rev Clin Esp
- Page 662 and 663: ZOLPIDEM Trade names: Ambien (Sanof
- Page 664 and 665: DRUGS RESPONSIBLE FOR COMMON REACTI
- Page 666 and 667: Ethambutol Ethanolamine Etoposide F
- Page 668 and 669: Procarbazine Progestins Promethazin
- Page 670 and 671: Erlotinib Ertapenem Escitalopram Et
- Page 672 and 673: Feverfew Floxuridine Fluconazole Fl
- Page 674 and 675: Insulin glulisine Interferon alfa I
- Page 676 and 677: Acamprosate Acebutolol Acetaminophe
- Page 678 and 679: Amobarbital Amoxicillin Amphoterici
- Page 680 and 681: Spironolactone Streptomycin Sulface
- Page 682 and 683: Miconazole Midazolam Minocycline Mi
- Page 684 and 685: Heroin Hydralazine Hydrochlorothiaz
- Page 686 and 687: Nefazodone Nevirapine Niacin Nicoti
- Page 688 and 689: Mephenytoin Mercaptopurine Mesalami
- Page 690 and 691: Cephradine Cetuximab Chamomile Chlo
- Page 692 and 693: Oxaprozin Penicillin G Phenytoin Pi
- Page 694 and 695: Ritonavir Rofecoxib Saquinavir Sele
- Page 696 and 697: Chlorotrianisene Chlorpheniramine C
VERAPAMIL<br />
Trade names: APO-Verap; Arpamyl LP; Azupamil; Berkatens;<br />
Calan (Pfizer); Chronovera; Cordilox; Covera-HS (Pfizer);<br />
Geangin; Isoptin (Abbott); Isoptine; Nu-Verap; Tarka (Abbott);<br />
Veraken; Verelan (Schwarz)<br />
Indications: Angina, hypertension<br />
Category: Antiarrhythmic class IV; Calcium channel blocker<br />
Half-life: 2–8 hours<br />
Clinically important, potentially hazardous interactions<br />
with: acebutolol, amiodarone, aspirin, atenolol, atorvastatin,<br />
betaxolol, carbamazepine, carteolol, clonidine, dantrolene,<br />
digoxin, dofetilide, epirubicin, eplerenone, erythromycin,<br />
esmolol, eucalyptus, lovastatin, metoprolol, mistletoe, nadolol,<br />
penbutolol, pindolol, propranolol, quinidine, ranolazine,<br />
sibutramine, simvastatin, timolol<br />
Tarka is tr<strong>and</strong>olapril <strong>and</strong> verapamil<br />
Reactions<br />
Skin<br />
Acne<br />
(1989): Stern R+, Arch Intern Med 149, 829<br />
Acute febrile neutrophilic dermatosis (Sweet’s syndrome)<br />
(1998): Knowles S+, JAmAcadDermatol38, 201 (passim)<br />
Angioedema<br />
(1998): Knowles S+, JAmAcadDermatol38, 201 (passim)<br />
(1989): Sadick NS+, JAmAcadDermatol21, 132<br />
(1989): Stern R+, Arch Intern Med 149, 829<br />
Dermatitis<br />
Diaphoresis (
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