Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

572 VECURONIUM
VECURONIUM
Trade names: Norcuron; Vecuron
Indications: Adjunct to general anesthesia
Category: Non-depolarizing neuromuscular blocker
Half-life: 65–75 minutes
Clinically important, potentially hazardous interactions
with: aminoglycosides, betamethasone, cyclosporine, gentamicin,
halothane, inhalational anesthetics, kanamycin, magnesium salts,
neomycin, quinidine, streptomycin, succinylcholine, tobramycin
Reactions
Other
Anaphylactoid reactions/Anaphylaxis
(2005): Bhananker SM+, Anesth Analg 101(3), 819
(2005): Karila C+, Allergy 60(6), 828
(1994): Watkins J, Acta Anaesthesiol Scand Suppl 102, 6
(1993): Yagi T+, Masui 42(4), 598
(1990): Treuren BC+, Br J Anaesth 64(1), 125
(1988): Charlton SM, Anaesthesia 43(8), 707
(1988): Farrell AM+, Anaesthesia 43(3), 207
(1988): Holt AW+, Anaesth Intensive Care 16(3), 378
(1988): Thacker MA+, Anaesth Intensive Care 16(1), 129
Hypersensitivity
(2004): Sanchez Palacios A+, Allergol Immunopathol (Madr)
32(6), 352
Injection-site pain
(2003): Blunk JA+, Eur J Anaesthesiol 20(3), 245
(1998): Ti LK+, Br J Anaesth 81(3), 487
(1995): Chow LH+, Zhonghua Yi Xue Za Zhi 55(4), 315
(1988): Kent AP+, Anaesthesia 43(4), 334
Neurotoxicity
(2001): Geller TJ+, Neuromuscul Disord 11(6-7), 579
VENLAFAXINE
Trade name: Effexor (Wyeth)
Indications: Depression
Category: Antidepressant, bicyclic; Serotonin-norepinephrine
reuptake inhibitor
Half-life: 3–7 hours
Clinically important, potentially hazardous interactions
with: isocarboxazid, linezolid, MAO inhibitors, metoclopramide,
phenelzine, selegiline, sibutramine, sumatriptan, tramadol,
tranylcypromine, trazodone, trimipramine
Reactions
Skin
Acne (