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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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TRIMETHOPRIM*<br />

Trade names: Abaprim; Alprim; Bactin; Bactrim (Women First);<br />

Idotrim; Ipral; Lidaprim; Methoprim; Monotrim; Polytrim;<br />

Primosept; Septra (Monarch); Syraprim; Tiempe; Triprim;<br />

Unitrim<br />

Indications: Various urinary tract infections caused by<br />

susceptible organisms<br />

Category: Antibiotic, sulfonamide<br />

Half-life: 8–10 hours<br />

Clinically important, potentially hazardous interactions<br />

with: dofetilide, methotrexate<br />

Reactions<br />

Skin<br />

Allergic reactions (sic)<br />

(2004): Karpman E+, JUrol172(2), 448<br />

Erythema multiforme<br />

Erythema nodosum<br />

(1983): Ugeskr Laeger (Danish) 145, 1070<br />

Exanthems<br />

Exfoliative dermatitis (

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