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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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*Note: Trichlormethiazide is a sulfonamide <strong>and</strong> can be absorbed<br />

systemically. Sulfonamides can produce severe, possibly fatal,<br />

reactions such as toxic epidermal necrolysis <strong>and</strong> Stevens–Johnson<br />

syndrome<br />

TRIENTINE<br />

Trade name: Syprine (Merck)<br />

Indications: Wilson’s disease<br />

Category: Chelator<br />

Half-life: N/A<br />

Reactions<br />

Skin<br />

Dermatitis<br />

(1980): Rudzki E, Contact Dermatitis 6, 235<br />

Desquamation<br />

Lupus erythematosus (

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