Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Eyes
Conjunctivitis (allergic contact)
(1998): Allergy 53(3):333
(1988): Tosti A+, Contact Dermatitis 18(5), 268 (eye drops)
(1980): van Ketel WG+, Contact Dermatitis 6(5), 321 (soft
contact lens)
Eyelid dermatitis
(1999): Wolfe, S, Statesville, NC (from Internet) (observation)
(1990): de Groot AC+, Contact Dermatitis 23(3), 168 (from
contact lens fluid)
Other
Hypersensitivity (local)
(2007): Fagundes A+, Acta Trop 101(1), 25
(2006): Zoller L+, Contact Dermatitis 55(4), 227
(2001): Ball LK+, Pediatrics 107(5):1147
(2001): van’t Veen AJ, Drugs 61(5), 565
(1994): van’t Veen AJ+, Contact Dermatitis 31(5), 293
(1991): Aberer W, Contact Dermatitis 24(1), 6
(1991): Noel I+, Lancet 338(8768), 705 (in hepatitis B vaccine)
(1991): Osawa J+, Contact Dermatitis 24(3), 178
(1990): Rietschel RL+, Dermatol Clin 8(1), 161
(1989): Tosti A+, Contact Dermatitis 20(3), 173
(1980): Forstrom L+, Contact Dermatitis 6(4), 241
Injection-site pain
(1984): Lindemayr H+, Hautarzt 35, 192
Injection-site urticaria
(1988): Bork K, CutaneousSideEffectsOfDrugsWB
Saunders, 114
Systemic reactions (sic)
(1986): Tosti A+, Contact Dermatitis 15(3), 187
THIOGUANINE
Synonyms: TG; 6-TG; 6-thioguanine; tioguanine
Trade name: Lanvis
Indications: Leukemias
Category: Antimetabolite; Antineoplastic
Half-life: 11 hours
Clinically important, potentially hazardous interactions
with: aldesleukin, vaccines
Reactions
Skin
Exanthems
(1988): Zimm S+, J Clin Oncol 6, 696
Malignancies
(1997): Zackheim HS+, JAmAcadDermatol30, 452
(nonmelanoma)
Palmar erythema
(1988): Shall L+, Br J Dermatol 119, 249
Petechiae
Photosensitivity (