Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
TETRACYCLINE Trade names: Apo-Tetra; Economycin; Florocycline; Helidac (Prometheus); Steclin; Sumycin (Par); Teflin; Teline; Tetramig; Topicycline (Topical); Zorbenal-G Indications: Various infections caused by susceptible organisms Category: Antibiotic, tetracycline Half-life: 6–11 hours Clinically important, potentially hazardous interactions with: acitretin, aluminum hydroxide, amoxicillin, ampicillin, antacids, bacampicillin, betamethasone, bismuth, bromelain, calcium, carbenicillin, cholestyramine, cloxacillin, corticosteroids, dairy products, dicloxacillin, didanosine, digoxin, food, iron, isotretinoin, methicillin, methotrexate, methoxyflurane, mezlocillin, nafcillin, oxacillin, penicillins, piperacillin, retinoids, rocuronium, sucralfate, ticarcillin, vitamin A, zinc Reactions Skin Acne Allergic granulomatous angiitis (Churg–Strauss syndrome) Angioedema (1997): Shapiro LE+, Arch Dermatol 133, 1224 Bullous dermatitis Dermatitis Diaphoresis Eczema Erythema multiforme (1988): Lewis-Jones MS+, Clin Exp Dermatol 13, 245 (1987): Curley RK+, Clin Exp Dermatol 12, 124 (1987): Leroy D+, Photodermatol 4, 52 (photodistributed) (1987): Shoji A+, Arch Dermatol 123, 18 (1983): Albengres E+, Therapie (French) 38, 577 Exanthems (1993): Chaffins ML+, JAmAcadDermatol28, 988 Exfoliative dermatitis (
532 TETRACYCLINE (1983): Ibsen HH+, Acta Derm Venereol 63, 555 Eyes Conjunctival pigmentation (1981): Brothers DM+, Ophthalmology 88, 1212 Ocular pigmentation (2006): Lapid-Gortzak R+, Cornea 25(8), 969 Other Anaphylactoid reactions/Anaphylaxis (
- Page 556 and 557: Tongue pigmentation Vulvovaginal ca
- Page 558 and 559: Reactions Skin Acne (
- Page 560 and 561: RIZATRIPTAN Synonym: MK462 Trade na
- Page 562 and 563: Glossitis (1%) Stomatitis (
- Page 564 and 565: (1995): Brandstatter G+, Clin Ther
- Page 566 and 567: Mucosal Cheilitis (
- Page 568 and 569: SELENIUM Trade names: Bio-Active Se
- Page 570 and 571: Mucosal Aphthous stomatitis (
- Page 572 and 573: (2004): Vasconcelos OM+, Muscle Ner
- Page 574 and 575: (2005): Mahe E+, Transplantation 79
- Page 576 and 577: SOLIFENACIN Trade name: Vesicare (G
- Page 578 and 579: Urticaria (
- Page 580 and 581: Pruritus (1997): Golsch S+, Hautarz
- Page 582 and 583: Glossitis (2%) Oral mucosal eruptio
- Page 584 and 585: Reactions Skin Allergic reactions (
- Page 586 and 587: (1995): Hertl M+, Br J Dermatol 132
- Page 588 and 589: (1992): Bodokh I+, Presse Med (Fren
- Page 590 and 591: SULFISOXAZOLE* Trade names: Isoxazi
- Page 592 and 593: (1984): Stern RS+, JAMA 252, 1433 J
- Page 594 and 595: TACROLIMUS Synonym: FK506 Trade nam
- Page 596 and 597: (2005): Fumal I+, Dermatology 210(3
- Page 598 and 599: (2000): Ernst E+, Forsch Komplement
- Page 600 and 601: Reactions Skin Allergic reactions (
- Page 602 and 603: Reactions Skin Diaphoresis (>1%) Ed
- Page 604 and 605: Mucosal Oral ulceration (1987): Hig
- Page 608 and 609: Xerosis (2002): Bariol C+, J Gastro
- Page 610 and 611: Eyes Conjunctivitis (allergic conta
- Page 612 and 613: Other Anaphylactoid reactions/Anaph
- Page 614 and 615: (2000): Chemnitz JM+, Med Klin (Ger
- Page 616 and 617: Note: Cutaneous side-effects of bet
- Page 618 and 619: Other Cough (0.8%) Fever (4.6%) Hep
- Page 620 and 621: TOLAZAMIDE* Trade names: Diabewas;
- Page 622 and 623: Reactions Skin Erythema (1.9%) Fung
- Page 624 and 625: TOSITUMOMAB & IODINE 131 Trade name
- Page 626 and 627: (2001): Vogel CL+, Oncology 61, 37
- Page 628 and 629: (1997): Gilchrest BA, JAmAcadDermat
- Page 630 and 631: Erythema (1999): Alexiou C+, Laryng
- Page 632 and 633: *Note: Trichlormethiazide is a sulf
- Page 634 and 635: TRIMETHOPRIM* Trade names: Abaprim;
- Page 636 and 637: Myalgia/Myositis/Myopathy/Myotoxici
- Page 638 and 639: Other Death (2002): Avarello TP+, N
- Page 640 and 641: (2001): Pechlaner C+, Blood Coagul
- Page 642 and 643: Bullous dermatitis (2001): Christ E
- Page 644 and 645: (1985): Schifter S+, Lancet 2, 499
- Page 646 and 647: Reactions Skin Allergic reactions (
- Page 648 and 649: VERAPAMIL Trade names: APO-Verap; A
- Page 650 and 651: Mucosal Gingival hyperplasia/hypert
- Page 652 and 653: (2001): Laack E+, Ann Oncol 12(12),
- Page 654 and 655: Fixed eruption (
TETRACYCLINE<br />
Trade names: Apo-Tetra; Economycin; Florocycline; Helidac<br />
(Prometheus); Steclin; Sumycin (Par); Teflin; Teline; Tetramig;<br />
Topicycline (Topical); Zorbenal-G<br />
Indications: Various infections caused by susceptible organisms<br />
Category: Antibiotic, tetracycline<br />
Half-life: 6–11 hours<br />
Clinically important, potentially hazardous interactions<br />
with: acitretin, aluminum hydroxide, amoxicillin, ampicillin,<br />
antacids, bacampicillin, betamethasone, bismuth, bromelain,<br />
calcium, carbenicillin, cholestyramine, cloxacillin, corticosteroids,<br />
dairy products, dicloxacillin, didanosine, digoxin, food, iron,<br />
isotretinoin, methicillin, methotrexate, methoxyflurane,<br />
mezlocillin, nafcillin, oxacillin, penicillins, piperacillin, retinoids,<br />
rocuronium, sucralfate, ticarcillin, vitamin A, zinc<br />
Reactions<br />
Skin<br />
Acne<br />
Allergic granulomatous angiitis (Churg–Strauss syndrome)<br />
Angioedema<br />
(1997): Shapiro LE+, Arch Dermatol 133, 1224<br />
Bullous dermatitis<br />
Dermatitis<br />
Diaphoresis<br />
Eczema<br />
Erythema multiforme<br />
(1988): Lewis-Jones MS+, Clin Exp Dermatol 13, 245<br />
(1987): Curley RK+, Clin Exp Dermatol 12, 124<br />
(1987): Leroy D+, Photodermatol 4, 52 (photodistributed)<br />
(1987): Shoji A+, Arch Dermatol 123, 18<br />
(1983): Albengres E+, Therapie (French) 38, 577<br />
Exanthems<br />
(1993): Chaffins ML+, JAmAcadDermatol28, 988<br />
Exfoliative dermatitis (
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