Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

(2005): Fumal I+, Dermatology 210(3), 251
Peripheral edema
Photo-recall
(1999): Bostrom A+, Acta Oncol 38, 955
(1992): Parry BR, Lancet 340, 49
Pruritus
(1980): Pritchard KI+, Cancer Treat Rep 64, 787
Pruritus ani et vulvae
(1980): Pritchard KI+, Cancer Treat Rep 64, 787
Purpura
Radiodermatitis
(2006): Kundranda MN+, Am J Clin Oncol 29(6), 637
Rash (sic) (1–10%)
Sarcoma
(2006): ACOG, Obstet Gynecol 107(6), 1475 (uterine)
(2006): Arenas M+, Int J Gynecol Cancer 16(2), 861 (uterine) (3
cases)
(2006): Atallah D+, Obstet Gynecol 108(3 Pt 2), 762 (uterine)
(2006): Botsis D+, Int J Gynecol Pathol 25(2), 173 (uterine)
(2006): Liu IF+, Taiwan J Obstet Gynecol 45(2), 167 (uterine)
(2006): Mouridsen HT, Curr Med Res Opin 22(8), 1609
(2006): Oztekin O+, Int J Gynecol Cancer 16(4), 1694
(endometrial)
(2006): Uray IP+, Expert Opin Investig Drugs 15(12), 1583
(uterine)
Urticaria
Vasculitis
(2006): Baptista MZ+, J Clin Oncol 24(21), 3504
(1994): Rzany B+, JAmAcadDermatol30, 509
(1990): Drago F+, AnnInternMed112, 965
Xerosis (7%)
Mucosal
Vaginal pruritus
Xerostomia (7%)
Hair
Hair – alopecia
(2001): Puglisi F+, AnnInternMed134(12), 1154 (total)
(1993): Litt JZ, Beachwood, OH (personal case) (observation)
(1980): Pritchard KI+, Cancer Treat Rep 64, 787
Hair – hirsutism
(1980): Pritchard KI+, Cancer Treat Rep 64, 787
Hair – hypertrichosis
Hair – pigmentation
(1995): Hampson JP+, Br J Dermatol 132, 483
Eyes
Cataract
(2003): Parkkari M+, Acta Ophthalmol Scand 81(5), 495 (7%)
Keratopathy
(2006): Zinchuk O+, Arch Ophthalmol 124(7), 1046
Maculopathy
(2003): Parkkari M+, Acta Ophthalmol Scand 81(5), 495
Ocular allergy (sic)
(2003): Parkkari M+, Acta Ophthalmol Scand 81(5), 495
Ocular toxicity
(2006): Muftuoglu O+, Eye Contact Lens 32(5), 228
(2005): Cronin BG+, Int Ophthalmol 26(3), 101
Other
Hepatotoxicity
(2007): Osman KA+, Expert Opin Drug Saf 6(1), 1 (40%)
(2006): Ahmed MH+, Pathology 38(3), 270
(2006): Liu CL+, Anticancer Drugs 17(6), 709
Hot flashes
(2007): Coates AS+, J Clin Oncol 25(5), 486
(2006): Garreau JR+, Am J Surg 192(4), 496 (35%)
(2006): Land SR+, JAMA 295(23), 2742
(2006): Sestak I+, J Clin Oncol 24(24), 3991
(2006): Uray IP+, Expert Opin Investig Drugs 15(12), 1583
(2003): Goetz MP+, J Natl Cancer Inst 95(23), 1734
(2002): Kinsinger LS+, AnnInternMed137(1), 59
(2001): Vogel NE+, Ned Tijdschr Geneeskd 145(22), 1041
Myalgia/Myositis/Myopathy/Myotoxicity
(1982): Harris AL+, BMJ 284, 1674
Thrombophlebitis
(1996): Zimmet S, The Schoch Letter 46, 22 (#86) (observation)
Thrombosis
(2007): Coates AS+, J Clin Oncol 25(5), 486
(2007): Cuzick J+, J Natl Cancer inst 99(4), 272
(2007): Osman KA+, Expert Opin Drug Saf 6(1), 1
(2006): Pritchard KI+, Drugs 66(13), 1727
(2006): Uray IP+, Expert Opin Investig Drugs 15(12), 1583
TAMSULOSIN
Trade name: Flomax (Boehringer Ingelheim)
Indications: Benign prostatic hypertrophy
Category: Adrenergic alpha-receptor antagonist
Half-life: 9–13 hours
Clinically important, potentially hazardous interactions
with: vardenafil
Reactions
Skin
Angioedema
Eczema
(2000): Frederickson KS, Novalo, CA (from Internet)
(observation)
Erythema multiforme
(1999): Reed BR, Denver, CO (from Internet) (observation)
Pruritus
Rash (sic)
Eyes
Floppy iris syndrome
(2007): Chadha V+, Br J Ophthalmol 91(1), 40 (57%)
(2007): Oshika T+, Am J Ophthalmol 143(1), 150 (43%)
(2007): Shapiro BL+, Am J Ophthalmol 143(2), 351
(2006): Allen D+, J Cataract Refract Surg 32(11), 1899
(2006): Arshinoff SA, J Cataract Refract Surg 32(4), 559
(2006): Bendel RE+, J Cataract Refract Surg 32(10), 1603
(2006): Cheung CM+, J Cataract Refract Surg 32(8), 1336 (35%)
(2006): Lawrentschuk N+, BJU Int 97(1), 2
(2006): Lim LA+, J Cataract Refract Surg 32(10), 1777
(2006): Nguyen DQ+, BJU Int 97(1), 197
(2006): Parssinen O+, Invest Ophthalmol Vis Sci 47(9), 3766
(2005): Chang DF+, J Cataract Refract Surg 31(4), 664 (2%)
(2005): Kershner RM, J Cataract Refract Surg 31(12), 2239
(2005): Nguyen DQ+, J Cataract Refract Surg 31(12), 2240
TARTRAZINE
TARTRAZINE 521
Synonyms: Acid Yellow T; Acilan Yellow GG; Cake Yellow;
Tartar Yellow S; Wool Yellow
Trade names: E102; FD&C yellow No.5
Category: Food additive
Half-life: N/A