Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Glossitis (2%) Oral mucosal eruption Oral ulceration Stomatitis Tongue black Hair Hair – hypertrichosis (1992): Shelley WB+, Advanced Dermatologic Diagnosis WB Saunders, 725 (passim) Other Anaphylactoid reactions/Anaphylaxis (2002): Romano A+, Allergy 57(11), 1087 DRESS syndrome (2004): Passeron T+, Acta Derm Venereol 84(1), 92 Embolia cutis medicamentosa (Nicolau syndrome) (2003): Reding EL+, JAmAcadDermatol48(3), 472 Injection-site granuloma Injection-site reactions (sic) Nephrotoxicity (2002): de Jager P+, Int J Tuberc Lung Dis 6(7), 622 Rhabdomyolysis (1992): Nakahara Y+, Nippon Jinzo Gakkai Shi 34(11), 1233 STREPTOZOCIN Trade name: Zanosar (Gensia) Indications: Carcinoma of the pancreas, carcinoid tumor, Hodgkin’s disease Category: Alkylating agent Half-life: 35 minutes Clinically important, potentially hazardous interactions with: aldesleukin Reactions Skin Edema Exanthems Pruritus Purpura Toxic epidermal necrolysis Other Injection-site erythema Injection-site necrosis (1987): Dufresne RG, Cutis 39, 197 Injection-site pain (1–10%) Nephrotoxicity (2001): Kintzel PE, Drug Saf 24(1), 19 (1988): Hricik DE+, Am J Med 84(1), 153 SUCCIMER Synonyms: dimercaptosuccinic acid; DMSA Trade name: Chemet (Sanofi-Aventis) Indications: Heavy metal poisoning Category: Chelator Half-life: 2 days Clinically important, potentially hazardous interactions with: other chelating agents Reactions Skin Exanthems (11%) Pruritus (11%) Rash (sic) (
508 SUCCINYLCHOLINE (2003): Schreiber JU+, Anesth Analg 96(6), 1640 (2002): Amornyotin S+, J Med Assoc Thai 85, S969 (1996): van den Berg AA+, Anaesth Intensive Care 24, 116 (1990): Shoji S, Nippon Rinsho (Japanese) 48, 1517 Rhabdomyolysis (2005): Escudero A+, Rev Esp Anestesiol Reanim 52(3), 184 (2001): Gronert GA, Anesthesiology 94(3), 523 (2000): Le Puura+, Acta Anaesthesiol Belg 51(1), 51 (2000): Matthews JM, Anesth Analg 91(6), 1552 (2000): Shaaban MJ+, Middle East J Anesthesiology 15(6), 681 (1996): Fiacchino F, Anesthesiology 84(2), 480 (1996): Pedrozzi NE+, Pediatr Neurol 15(3), 254 (2 cases) (1996): Perret D+, AnnFrAnesthReanim15(8), 1193 (1996): Takamatsu F+, Masui 45(11), 1406 (1995): Friedman S+, Anesth Analg 81(2), 422 (1995): Schulte-Sasse U, HNO 43(11), 676 (1994): Sullivan M+, Can J Anaesth 41(6), 497 (1993): Bhave CG+, JPostgradMed39(3), 157 (1992): Bakshi KK, J Assoc Physicians India 40(8), 549 (1991): Gokhale YA+, J Assoc Physicians India 39(12), 968 (1987): Lee SC+, J Oral Maxillofac Surg 45(9), 789 (with enflurane) (1987): Lee SC+, Ma Zui Xue Za Zhi 25(2), 97 (1985): Hawker F+, Anaesth Intensive Care 13(2), 208 (1985): Sodano R+, Minerva Anestesiol 51(3), 109 (1984): Blumberg A+, Schweiz Med Wochenschr 114(30), 1068 (2 cases) (1984): Hool GJ+, Anaesth Intensive Care 12(4), 360 (1981): Lewandowski KB, Br J Anaesth 53(9), 981 SUCRALFATE Trade names: Antepsin; Carafate (Axcan); Sucrabest; Sulcrate; Ulcar; Ulcogant; Ulcyte; Urbal Indications: Duodenal ulcer Category: Chelator Half-life: N/A Clinically important, potentially hazardous interactions with: ciprofloxacin, clorazepate, ketoconazole, lansoprazole, lomefloxacin, phenytoin, sparfloxacin, tetracycline Note: Sucralfate use can lead to symptoms of aluminium toxicity Reactions Skin Angioedema Exanthems (1984): Brogden RN+, Drugs 17, 233 Facial edema Pruritus (
- Page 532 and 533: (1982): Gall H+, Derm Beruf Umwelt
- Page 534 and 535: (2006): Barkin RL+, Am J Ther 13(6)
- Page 536 and 537: PROTAMINE SULFATE Indications: Hepa
- Page 538 and 539: (1987): Shelley WB+, JAmAcadDermato
- Page 540 and 541: Hypersensitivity Myalgia/Myositis/M
- Page 542 and 543: (1999): Drayton G, Los Angeles, CA
- Page 544 and 545: (1986): Bigby M+, JAMA 256, 3358 (1
- Page 546 and 547: Nails Nails - photo-onycholysis (19
- Page 548 and 549: Hair Hair - alopecia (1-10%) Other
- Page 550 and 551: RASBURICASE Trade names: Elitek (Sa
- Page 552 and 553: RETEPLASE Synonyms: recombinant pla
- Page 554 and 555: Other Inappropriate secretion of an
- Page 556 and 557: Tongue pigmentation Vulvovaginal ca
- Page 558 and 559: Reactions Skin Acne (
- Page 560 and 561: RIZATRIPTAN Synonym: MK462 Trade na
- Page 562 and 563: Glossitis (1%) Stomatitis (
- Page 564 and 565: (1995): Brandstatter G+, Clin Ther
- Page 566 and 567: Mucosal Cheilitis (
- Page 568 and 569: SELENIUM Trade names: Bio-Active Se
- Page 570 and 571: Mucosal Aphthous stomatitis (
- Page 572 and 573: (2004): Vasconcelos OM+, Muscle Ner
- Page 574 and 575: (2005): Mahe E+, Transplantation 79
- Page 576 and 577: SOLIFENACIN Trade name: Vesicare (G
- Page 578 and 579: Urticaria (
- Page 580 and 581: Pruritus (1997): Golsch S+, Hautarz
- Page 584 and 585: Reactions Skin Allergic reactions (
- Page 586 and 587: (1995): Hertl M+, Br J Dermatol 132
- Page 588 and 589: (1992): Bodokh I+, Presse Med (Fren
- Page 590 and 591: SULFISOXAZOLE* Trade names: Isoxazi
- Page 592 and 593: (1984): Stern RS+, JAMA 252, 1433 J
- Page 594 and 595: TACROLIMUS Synonym: FK506 Trade nam
- Page 596 and 597: (2005): Fumal I+, Dermatology 210(3
- Page 598 and 599: (2000): Ernst E+, Forsch Komplement
- Page 600 and 601: Reactions Skin Allergic reactions (
- Page 602 and 603: Reactions Skin Diaphoresis (>1%) Ed
- Page 604 and 605: Mucosal Oral ulceration (1987): Hig
- Page 606 and 607: TETRACYCLINE Trade names: Apo-Tetra
- Page 608 and 609: Xerosis (2002): Bariol C+, J Gastro
- Page 610 and 611: Eyes Conjunctivitis (allergic conta
- Page 612 and 613: Other Anaphylactoid reactions/Anaph
- Page 614 and 615: (2000): Chemnitz JM+, Med Klin (Ger
- Page 616 and 617: Note: Cutaneous side-effects of bet
- Page 618 and 619: Other Cough (0.8%) Fever (4.6%) Hep
- Page 620 and 621: TOLAZAMIDE* Trade names: Diabewas;
- Page 622 and 623: Reactions Skin Erythema (1.9%) Fung
- Page 624 and 625: TOSITUMOMAB & IODINE 131 Trade name
- Page 626 and 627: (2001): Vogel CL+, Oncology 61, 37
- Page 628 and 629: (1997): Gilchrest BA, JAmAcadDermat
- Page 630 and 631: Erythema (1999): Alexiou C+, Laryng
508 SUCCINYLCHOLINE<br />
(2003): Schreiber JU+, Anesth Analg 96(6), 1640<br />
(2002): Amornyotin S+, J Med Assoc Thai 85, S969<br />
(1996): van den Berg AA+, Anaesth Intensive Care 24, 116<br />
(1990): Shoji S, Nippon Rinsho (Japanese) 48, 1517<br />
Rhabdomyolysis<br />
(2005): Escudero A+, Rev Esp Anestesiol Reanim 52(3), 184<br />
(2001): Gronert GA, Anesthesiology 94(3), 523<br />
(2000): Le Puura+, Acta Anaesthesiol Belg 51(1), 51<br />
(2000): Matthews JM, Anesth Analg 91(6), 1552<br />
(2000): Shaaban MJ+, Middle East J Anesthesiology 15(6), 681<br />
(1996): Fiacchino F, Anesthesiology 84(2), 480<br />
(1996): Pedrozzi NE+, Pediatr Neurol 15(3), 254 (2 cases)<br />
(1996): Perret D+, AnnFrAnesthReanim15(8), 1193<br />
(1996): Takamatsu F+, Masui 45(11), 1406<br />
(1995): Friedman S+, Anesth Analg 81(2), 422<br />
(1995): Schulte-Sasse U, HNO 43(11), 676<br />
(1994): Sullivan M+, Can J Anaesth 41(6), 497<br />
(1993): Bhave CG+, JPostgradMed39(3), 157<br />
(1992): Bakshi KK, J Assoc Physicians India 40(8), 549<br />
(1991): Gokhale YA+, J Assoc Physicians India 39(12), 968<br />
(1987): Lee SC+, J Oral Maxillofac Surg 45(9), 789 (with<br />
enflurane)<br />
(1987): Lee SC+, Ma Zui Xue Za Zhi 25(2), 97<br />
(1985): Hawker F+, Anaesth Intensive Care 13(2), 208<br />
(1985): Sodano R+, Minerva Anestesiol 51(3), 109<br />
(1984): Blumberg A+, Schweiz Med Wochenschr 114(30), 1068<br />
(2 cases)<br />
(1984): Hool GJ+, Anaesth Intensive Care 12(4), 360<br />
(1981): Lew<strong>and</strong>owski KB, Br J Anaesth 53(9), 981<br />
SUCRALFATE<br />
Trade names: Antepsin; Carafate (Axcan); Sucrabest; Sulcrate;<br />
Ulcar; Ulcogant; Ulcyte; Urbal<br />
Indications: Duodenal ulcer<br />
Category: Chelator<br />
Half-life: N/A<br />
Clinically important, potentially hazardous interactions<br />
with: ciprofloxacin, clorazepate, ketoconazole, lansoprazole,<br />
lomefloxacin, phenytoin, sparfloxacin, tetracycline<br />
Note: Sucralfate use can lead to symptoms of aluminium toxicity<br />
Reactions<br />
Skin<br />
Angioedema<br />
Exanthems<br />
(1984): Brogden RN+, <strong>Drug</strong>s 17, 233<br />
Facial edema<br />
Pruritus (
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