Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Mucosal Aphthous stomatitis (
496 SIBUTRAMINE Peripheral edema (>1%) Pruritus (>1%) Rash (sic) (3.8%) Xerosis (2003): Fanghanel G+, Adv Ther 20(2), 101 Mucosal Vulvovaginal candidiasis (1.2%) Xerostomia (17.2%) (2005): Milano W+, Adv Ther 22(1), 25 (2005): Violante-Ortiz R+, Adv Ther 22(6), 642 (2004): Kaya A+, Biomed Pharmacother 58(10), 582 (2003): Appolinario JC+, Arch Gen Psychiatry 60(11), 1109 (2001): Bray GA, Rev Endocr Metab Disord 2(4), 403 (2001): Scheen AJ, Rev Med Liege 56(9), 656 Other Death (2002): London, Reuters Health Information 3-26-02 (2 cases) Hepatotoxicity (2005): Chounta A+, AnnInternMed143(10), 763 Myalgia/Myositis/Myopathy/Myotoxicity (1.9%) SILDENAFIL Trade name: Viagra (Pfizer) Indications: Erectile dysfunction, Hypertension Category: Phosphodiesterase type 5 inhibitor Half-life: 4 hours Clinically important, potentially hazardous interactions with: amprenavir, amyl nitrite, atazanavir, delavirdine, erythromycin, fosamprenavir, indinavir, isosorbide dinitrate, isosorbide mononitrate, itraconazole, ketoconazole, nelfinavir, nitrates, nitroglycerin, ritonavir, saquinavir Reactions Skin Allergic reactions (sic) (
- Page 520 and 521: Reactions Skin Exanthems Petechiae
- Page 522 and 523: Reactions Skin Acne (1-10%) Angioed
- Page 524 and 525: Pruritus (
- Page 526 and 527: PREDNISONE Trade names: Deltasone (
- Page 528 and 529: Other Anticonvulsant hypersensitivi
- Page 530 and 531: Xerosis Mucosal Lip ulceration (198
- Page 532 and 533: (1982): Gall H+, Derm Beruf Umwelt
- Page 534 and 535: (2006): Barkin RL+, Am J Ther 13(6)
- Page 536 and 537: PROTAMINE SULFATE Indications: Hepa
- Page 538 and 539: (1987): Shelley WB+, JAmAcadDermato
- Page 540 and 541: Hypersensitivity Myalgia/Myositis/M
- Page 542 and 543: (1999): Drayton G, Los Angeles, CA
- Page 544 and 545: (1986): Bigby M+, JAMA 256, 3358 (1
- Page 546 and 547: Nails Nails - photo-onycholysis (19
- Page 548 and 549: Hair Hair - alopecia (1-10%) Other
- Page 550 and 551: RASBURICASE Trade names: Elitek (Sa
- Page 552 and 553: RETEPLASE Synonyms: recombinant pla
- Page 554 and 555: Other Inappropriate secretion of an
- Page 556 and 557: Tongue pigmentation Vulvovaginal ca
- Page 558 and 559: Reactions Skin Acne (
- Page 560 and 561: RIZATRIPTAN Synonym: MK462 Trade na
- Page 562 and 563: Glossitis (1%) Stomatitis (
- Page 564 and 565: (1995): Brandstatter G+, Clin Ther
- Page 566 and 567: Mucosal Cheilitis (
- Page 568 and 569: SELENIUM Trade names: Bio-Active Se
- Page 572 and 573: (2004): Vasconcelos OM+, Muscle Ner
- Page 574 and 575: (2005): Mahe E+, Transplantation 79
- Page 576 and 577: SOLIFENACIN Trade name: Vesicare (G
- Page 578 and 579: Urticaria (
- Page 580 and 581: Pruritus (1997): Golsch S+, Hautarz
- Page 582 and 583: Glossitis (2%) Oral mucosal eruptio
- Page 584 and 585: Reactions Skin Allergic reactions (
- Page 586 and 587: (1995): Hertl M+, Br J Dermatol 132
- Page 588 and 589: (1992): Bodokh I+, Presse Med (Fren
- Page 590 and 591: SULFISOXAZOLE* Trade names: Isoxazi
- Page 592 and 593: (1984): Stern RS+, JAMA 252, 1433 J
- Page 594 and 595: TACROLIMUS Synonym: FK506 Trade nam
- Page 596 and 597: (2005): Fumal I+, Dermatology 210(3
- Page 598 and 599: (2000): Ernst E+, Forsch Komplement
- Page 600 and 601: Reactions Skin Allergic reactions (
- Page 602 and 603: Reactions Skin Diaphoresis (>1%) Ed
- Page 604 and 605: Mucosal Oral ulceration (1987): Hig
- Page 606 and 607: TETRACYCLINE Trade names: Apo-Tetra
- Page 608 and 609: Xerosis (2002): Bariol C+, J Gastro
- Page 610 and 611: Eyes Conjunctivitis (allergic conta
- Page 612 and 613: Other Anaphylactoid reactions/Anaph
- Page 614 and 615: (2000): Chemnitz JM+, Med Klin (Ger
- Page 616 and 617: Note: Cutaneous side-effects of bet
- Page 618 and 619: Other Cough (0.8%) Fever (4.6%) Hep
496 SIBUTRAMINE<br />
Peripheral edema (>1%)<br />
Pruritus (>1%)<br />
Rash (sic) (3.8%)<br />
Xerosis<br />
(2003): Fanghanel G+, Adv Ther 20(2), 101<br />
Mucosal<br />
Vulvovaginal c<strong>and</strong>idiasis (1.2%)<br />
Xerostomia (17.2%)<br />
(2005): Milano W+, Adv Ther 22(1), 25<br />
(2005): Violante-Ortiz R+, Adv Ther 22(6), 642<br />
(2004): Kaya A+, Biomed Pharmacother 58(10), 582<br />
(2003): Appolinario JC+, Arch Gen Psychiatry 60(11), 1109<br />
(2001): Bray GA, Rev Endocr Metab Disord 2(4), 403<br />
(2001): Scheen AJ, Rev Med Liege 56(9), 656<br />
Other<br />
Death<br />
(2002): London, Reuters Health Information 3-26-02 (2 cases)<br />
Hepatotoxicity<br />
(2005): Chounta A+, AnnInternMed143(10), 763<br />
Myalgia/Myositis/Myopathy/Myotoxicity (1.9%)<br />
SILDENAFIL<br />
Trade name: Viagra (Pfizer)<br />
Indications: Erectile dysfunction, Hypertension<br />
Category: Phosphodiesterase type 5 inhibitor<br />
Half-life: 4 hours<br />
Clinically important, potentially hazardous interactions<br />
with: amprenavir, amyl nitrite, atazanavir, delavirdine,<br />
erythromycin, fosamprenavir, indinavir, isosorbide dinitrate,<br />
isosorbide mononitrate, itraconazole, ketoconazole, nelfinavir,<br />
nitrates, nitroglycerin, ritonavir, saquinavir<br />
Reactions<br />
Skin<br />
Allergic reactions (sic) (
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