Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Mucosal Cheilitis (

492 SCOPOLAMINE (1985): Clissold SP+, Drugs 29, 189 (transdermal patch) Fixed eruption (1981): Kanwar AJ+, Dermatologica 162, 378 Photosensitivity (1–10%) Rash (sic) (10%) Mucosal Oral lesions (>5%) (1985): Clissold SP+, Drugs 29, 189 (transdermal patch) (>5%) Xerostomia (>60%) (2006): Nachum Z+, Clin Pharmacokinet 45(6), 543 (50%) (2002): Kranke P+, Anesth Analg 95(1), 133 (1989): Parrott AC, Aviat Space Environ Med 60(1), 1 (1985): Clissold SP+, Drugs 29, 189 (transdermal patch) (66%) (1985): van Marion WF+, Clin Pharmacol Ther 38(3), 301 (1981): Price NM+, Clin Pharmacol Ther 29, 414 Eyes Dilated pupils (2006): Firth AY+, Dev Med Child Neurol 48(2), 137 Reduced visual acuity (2006): Firth AY+, Dev Med Child Neurol 48(2), 137 Vision blurred (1989): Parrott AC, Aviat Space Environ Med 60(1), 1 Other Anaphylactoid reactions/Anaphylaxis (1995): Manhart AR+, J Toxicol Clin Toxicol 33, 189 (fatal) (1994): Watanabe F+, J Toxicol Clin Toxicol 32, 593 (fatal) Death Injection-site irritation (>10%) Note: Systemic adverse effects have been reported following ophthalmic administration SECOBARBITAL Synonym: quinalbarbitone Trade names: Immenoctal; Novo-Secobarb; Secanal; Seconal (Ranbaxy) Indications: Insomnia Category: Barbiturate Half-life: 15–40 hours Clinically important, potentially hazardous interactions with: alcohol, anticoagulants, antihistamines, brompheniramine, buclizine, chlorpheniramine, dicumarol, ethanolamine, imatinib, warfarin Reactions Skin Angioedema (

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Cheilitis (

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