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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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RIZATRIPTAN<br />

Synonym: MK462<br />

Trade name: Maxalt (Merck)<br />

Indications: Migraine<br />

Category: 5-HT1 agonist; Serotonin receptor agonist; Triptan<br />

Half-life: 2–3 hours<br />

Clinically important, potentially hazardous interactions<br />

with: dihydroergotamine, ergot-containing drugs, isocarboxazid,<br />

MAO inhibitors, methysergide, naratriptan, phenelzine,<br />

propanolol, sibutramine, St John’s wort, sumatriptan,<br />

tranylcypromine, zolmitriptan<br />

Reactions<br />

Skin<br />

Diaphoresis (

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