Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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RASBURICASE Trade names: Elitek (Sanofi-Aventis); Fasturtec; Uricozyme Indications: Hyperuricemia (associated with tumor lysis syndrome) Category: Antimetabolite; Urate oxidase Half-life: 18 hours Clinically important, potentially hazardous interactions with: N/A Reactions Skin Allergic reactions (sic) (

476 RED RICE YEAST Reactions Other Abdominal pain Anaphylactoid reactions/Anaphylaxis (1999): Wigger-Alberti W+, Allergy 54(12), 1330 Myalgia/Myositis/Myopathy/Myotoxicity (2003): Smith DJ+, South Med J 96(12), 1265 Rhabdomyolysis (2002): Prasad GV+, Transplantation 74(8), 1200 REPAGLINIDE Trade name: Prandin (Novo Nordisk) Indications: Non-insulin dependent diabetes type II Category: Meglitinide Half-life: 1 hour Clinically important, potentially hazardous interactions with: clarithromycin, erythromycin, gemfibrozil, grapefruit juice Reactions Skin Allergic reactions (sic) (2%) Other Anaphylactoid reactions/Anaphylaxis (

476 RED RICE YEAST<br />

Reactions<br />

Other<br />

Abdominal pain<br />

Anaphylactoid reactions/Anaphylaxis<br />

(1999): Wigger-Alberti W+, Allergy 54(12), 1330<br />

Myalgia/Myositis/Myopathy/Myotoxicity<br />

(2003): Smith DJ+, South Med J 96(12), 1265<br />

Rhabdomyolysis<br />

(2002): Prasad GV+, Transplantation 74(8), 1200<br />

REPAGLINIDE<br />

Trade name: Pr<strong>and</strong>in (Novo Nordisk)<br />

Indications: Non-insulin dependent diabetes type II<br />

Category: Meglitinide<br />

Half-life: 1 hour<br />

Clinically important, potentially hazardous interactions<br />

with: clarithromycin, erythromycin, gemfibrozil, grapefruit<br />

juice<br />

Reactions<br />

Skin<br />

Allergic reactions (sic) (2%)<br />

Other<br />

Anaphylactoid reactions/Anaphylaxis (

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