Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

458 PROPOLIS
PROPOLIS
Scientific name: Propolis
Family: None
Trade and other common names: Bee Glue; Bee Propolis;
Hive Dross; Propolis Balsam; Propolis Resin; Propolis Wax;
Russian Penicillin
Category: Immunomodulator
Purported indications and other uses: Tuberculosis, bacterial,
fungal and protozoal infections, nasopharyngeal carcinoma,
duodenal ulcer, Helicobacter pylori infection, cold, wound
cleansing, mouth rinse, genital herpes. Ingredient in cosmetics
Half-life: N/A
Reactions
Skin
Allergic reactions (sic)
(2002): Junghans V+, Am J Contact Dermat 13(2), 87
(2001): Callejo A+, Allergy 56(6), 579
(1996): Bellagrandi S+, JAmAcadDermatol35(4), 644 (in HIVpositive
patient)
(1988): Hausen BM+, Contact Dermatitis 19(4), 296
(1988): Slezak R, Prakt Zubn Lek 36(7), 208
(1987): Blanken R+, Ned Tijdschr Geneeskd 131(26), 1121
(1987): Rudzki E+, Przegl Dermatol 19(4), 296
Dermatitis
(2006): Lee SY+, J Drugs Dermatol 5(5), 458
(2005): Black RJ, Clin Exp Dermatol 30(1), 91
(2005): Walgrave SE+, Dermatitis 16(4), 209
(2004): Giusti F+, Contact Dermatitis 51(5-6), 255 (5.9%)
(2004): Ting PT+, JDrugsDermatol3(6), 685
(2003): Lombardi C+, Allerg Immunol (Paris) 35(2), 52
(2002): Henschel R+, Contact Dermatitis 47(1), 52
(2002): Lieberman HD+, JAmAcadDermatol46, S30
(2001): Teraki Y+, Br J Dermatol 144(6), 1277 (granulomatous)
(2000): Tumova L+, Ceska Slov Farm 49(6), 285
(1998): Burdock GA, Food Chem Toxicol 36(4), 347
(1998): Downs AM+, Contact Dermatitis 38(6), 359
(occupational)
(1998): Thomas P+, Arch Dermatol 134(4), 511
(1997): Silvani S+, Contact Dermatitis 37(1), 48 (in patients with
psoriasis)
(1990): Hegyi E+, Hautarzt 41(12), 675 (0.64%)
(1990): Raton JA+, Contact Dermatitis 22(3), 183
(1988): Schuler TM+, Hautarzt 39(3), 139 (6 patients)
(1987): Angelini G+, Contact Dermatitis 17(4), 251 (in psoriasis)
(1987): Cirasino L+, Contact Dermatitis 16(2)
(1987): Frosch PJ, ZHaut62(23), 1631
(1987): Hausen BM+, Contact Dermatitis 17(3), 163
(1987): Kleinhaus D, Contact Dermatitis 17(3), 187 (airborne)
(1987): Trevisan G+, Contact Dermatitis 16(1), 48
(1985): Ayala F+, Contact Dermatitis 12(3), 181
(1985): Machackova J, Contact Dermatitis 13(1), 43
(1985): Rudzki E+, Contact Dermatitis 13(3), 198
(1985): Tosti A+, Contacr Dermatitis 12(4), 227
(1984): Bedello PG+, G Ital Deramtol Venereol 119(6), 431
(1984): Pincelli C+, Contact Dermatitis 11(1), 49
(1984): Valsecchi R+, Contact Dermatitis 11(5), 317
(1983): Kokelj F+, Contact Dermatitis 9(6), 518
(1983): Melli MC+, Contact Dermatitis 9(5), 427 (in a beekeeper)
(1983): Monti M+, Contact Dermatitis 9(2), 163 (occupational
and cosmetic)
(1983): Rudzki E+, Contact Dermatitis 9(1), 40
(1983): Takahashi M+, Contact Dermatitis 9(6) (from honeybee
royal jelly)
(1982): Monti M+, G Ital Dermatol Venereol 117(2), 119
(1982): Proserpio G, G Ital Dermatol Venereol 117(5), 316
Eczema (vulval)
(2005): Black RJ, Clin Exp Dermatol 30(1), 91
Erythroderma
(2001): Horiuchi Y, Br J Dermatol 145, 691
Sensitivity (sic)
(1988): Nakamura T, Contact Dermatitis 18(5), 313
(1987): Young E, Contact Dermatitis 16(1), 49
(1980): Bogdaszewska-Czabanowska J+, Przegl Dermatol
67(6), 747
Mucosal
Cheilitis
(1996): Bellegrandi S+, JAmAcadDermatol35, 644
Mucositis
(1990): Hay KD+, Oral Surg Oral Med Oral Pathol 70, 584
Oral lesions
(2006): Brailo V+, Med Oral Patol Oral Cir Bucal 11(4), E303
Oral ulceration
(1990): Hay KD+, Oral Surg Oral Med Oral Pathol 70, 584
Stomatitis
(1996): Bellegrandi S+, JAmAcadDermatol35, 644
Other
Hypersensitivity
(1987): Rudzki E+, Pol Tyg Lek (Polish) 42(2), 40
(1984): Tosti A+, G Ital Dermatol Venereol 119(5)
PROPOXYPHENE
Trade names: Algafan; Antalvic; Darvocet-N (aaiPharma);
Darvon (Lilly); Darvon Compound (aaiPharma); Develin;
Dolotard; Doloxene; Liberan; Parvon
Indications: Pain
Category: Opiate agonist
Half-life: 8–24 hours
Clinically important, potentially hazardous interactions
with: alcohol, alprazolam, carbamazepine, metoprolol,
phenelzine, ritonavir, warfarin
Darvocet is propoxyphene and acetaminophen; Darvon Compound is
propoxyphene and aspirin
Reactions
Skin
Acute generalized exanthematous pustulosis (AGEP)
(2000): Machet L+, Acta Derm Venereol 80(3), 224
Diaphoresis
Exanthems
Facial edema
Pruritus
Rash (sic) (