Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

(1993): Leenutaphong V+, Int J Dermatol 32, 428
(1992): Lleonart R+, Med Clin (Barc) (Spanish) 99, 474
(1985): Avery JK, J Tenn Med Assoc 78, 764
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(2000): Devidal R+, Therapie 55, 225 (2 cases)
(1999): Rzany B+, Lancet 353, 2190
(1996): Blum L+, JAmAcadDermatol34, 1088
(1995): Wolkenstein P+, Arch Dermatol 131, 544
(1994): Errani A+, Br J Dermatol 131, 586
(1994): Shelley WB+, Cutis 53, 162 (observation)
(1993): Correia O+, Dermatology 186, 32
(1993): Leenutaphong V+, Int J Dermatol 32, 428
(1989): Dominguez-Perez F+, Rev Esp Anestesiol Reanim
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(1988): Shear NH+, J Clin Invest 82, 1826
(1987): Teillac D+, Arch Fr Pediatr (French) 44, 583
(1985): de Rego JA+, Hillside J Clin Psychiatry 7, 141
(1984): Chan HL, JAmAcadDermatol10, 973
Toxicoderma
(1998): Arima M+, Jpn Circ J 62, 132
Urticaria
Vasculitis
Mucosal
Gingival hyperplasia/hypertrophy
(2002): Sinha S+, J Neurol Neurosurg Psychiatry 73(5), 601
Oral ulceration
Xerostomia
Hair
Hair – poliosis
(1992): Mion N+, Ann Dermatol Venereol (French) 119, 927
Nails
Nails – hypoplasia
(1991): Thakker JC+, Indian Pediatr 28, 73
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Other
Anticonvulsant hypersensitivity syndrome
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(2004): Bavdekar SB+, Ann Pharmacother 2004 Oct;38(10), 1648
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Death
DRESS syndrome
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(2004): Allam JP+, Eur J Dermatol 14(5), 339
(2003): Baruzzi A+, Clin Neuropharmacol 26(4), 177
(2001): Lachgar T+, Allerg Immunol (Paris) 33(4), 173
(1997): Descamps V+, Br J Dermatol 137, 605
Hypersensitivity (10%)
Injection-site thrombophlebitis (>10%)
Pain
(2006): Tanabe Y, No To Shinkei 58(8), 687
Porphyria cutanea tarda
Porphyria variegata
Rhabdomyolysis
(1990): Larpin R+, Presse Med 19(30), 1403
PHENOLPHTHALEIN
PHENOLPHTHALEIN 433
Trade names: Agoral; Alophen; Bom-Bon; Bonomint; Caroid;
Correctol; Darmol; Doxidan; Easylax; Espotabs; Evac-U-Gen; Ex-
Lax (Novartis); Feen-A-Mint; Medilax; Phenolax; Prulet; Purganol;
Ruguletts; Trilax
Indications: Constipation
Category: Stimulant laxative
Half-life: N/A
Reactions
Skin
Angioedema
Bullous dermatitis
Diaphoresis
Erythema annulare
Erythema multiforme
(1992): Breathnach SM+, Adverse Drug Reactions and the Skin
Blackwell, Oxford, 344
Exanthems
Exfoliative dermatitis
Fixed eruption
(1997): Blumenthal HL, Beachwood, OH (personal case)
(observation)
(1993): Zanolli MD+, Pediatrics 91, 1199
(1991): Smoller BR+, JCutanPathol18, 13
(1990): Gaffoor PMA+, Cutis 45, 242
(1987): Stroud MB+, Arch Dermatol 123, 1227
(1986): Kanwar AJ+, Dermatologica 172, 315
(1985): Kauppinen K+, Br J Dermatol 112, 575
(1984): Chan HL, Int J Dermatol 23, 607
Lupus erythematosus
(1992): Breathnach SM+, Adverse Drug Reactions and the Skin
Blackwell, Oxford, 344
Perianal irritation
Pigmentation
Pruritus
Stevens–Johnson syndrome
Toxic epidermal necrolysis
(1997): Artymowicz RJ+, Ann Pharmacother 31, 1157
(1986): Kar PK+, J Indian Med Assoc 84, 189
Urticaria
Mucosal
Oral mucosal fixed eruption
Oral pigmentation
Oral ulceration
Nails
Nails – discoloration
(1984): Daniel CR+, JAmAcadDermatol10, 250