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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Other<br />

Anaphylactoid reactions/Anaphylaxis (10%)<br />

Toxic epidermal necrolysis<br />

(2001): van der Meer JB+, Clin Exp Dermatol 26(8), 654<br />

Urticaria<br />

Mucosal<br />

Sialopenia (>10%)<br />

Sialorrhea (1–10%)<br />

Tongue furry<br />

Xerostomia (>10%)<br />

Other<br />

DRESS syndrome<br />

(2004): Cordel N+, Ann Dermatol Venereol 131(12), 1059<br />

OXCARBAZEPINE<br />

Synonym: GP 47680<br />

Trade name: Trileptal (Novartis)<br />

Indications: Partial epileptic seizures<br />

Category: Anticonvulsant; Mood stabilizer<br />

Half-life: 1–2.5 hours<br />

Skin<br />

Acne<br />

Reactions<br />

OXCARBAZEPINE 409<br />

Allergic reactions (sic) (2%)<br />

(1994): Dam M, Epilepsia 35, S23<br />

(1993): Beran RG, Epilepsia 34, 163<br />

Angioedema<br />

Dermatitis<br />

Diaphoresis (3%)<br />

Eczema<br />

Edema (2%)<br />

Erythema multiforme<br />

Exanthems<br />

(2003): Warnock JK+, Am J Clin Dermatol 4(1), 21<br />

(1999): Ruble R+, CNS <strong>Drug</strong>s 12, 215<br />

Facial rash (sic)<br />

Folliculitis<br />

Genital pruritus<br />

Lupus erythematosus<br />

Photosensitivity<br />

Purpura (2%)<br />

Rash (sic) (

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