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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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(2007): Koulaouzidis A+, Ann Hepatol 6(2), 119<br />

(2006): Peedikayil MC+, Ann Pharmacother 40(10), 1888<br />

(2006): Salle V+, Rev Med Interne 27(4), 344<br />

Hypersensitivity<br />

Myalgia/Myositis/Myopathy/Myotoxicity<br />

Panniculitis (nodular nonsuppurative)<br />

(1987): Sanford RG+, Arthritis Rheum 30, 1076<br />

Pseudolymphoma<br />

(1993): Kerl H+, Dermatology in General Medicine McGraw-Hill<br />

New York<br />

NITROFURAZONE<br />

Trade names: Actin-N; Furacept; Furacin (Pharma Pac, Quality<br />

Care, Roberts, Southwood); Furacine; Nigermex; Nitrofurazone<br />

(Taro); Rafuzone<br />

Indications: Second- <strong>and</strong> third-degree burns, skin grafting<br />

Category: Antibiotic, nitrofuran<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: None<br />

Reactions<br />

Skin<br />

Allergic reactions (sic)<br />

Depigmentation (skin & eyelashes)<br />

Dermatitis<br />

(2006): Prieto A+, Contact Dermatitis 54(2), 126<br />

(1999): Guijarro SC+, Am J Contact Dermat 10(4), 226<br />

(1995): Conde-Salazar L+, Contact Dermatitis 32(5), 307<br />

(1994): Ballmer-Weber BK+, Contact Dermatitis 31(4), 274<br />

(1990): Lo JS+, Dermatol Clin 8(1), 165<br />

(1986): Bajaj AK+, Int J Dermatol 25(2), 103<br />

(1985): Ancona A, Contact Dermatitis 13(1), 35<br />

(1981): Burkhart CG, Cutis 27(6), 630 (pustular)<br />

Edema (~1%)<br />

Pruritus (~1%)<br />

Rash (sic) (~1%)<br />

NITROGLYCERIN<br />

Synonyms: glyceryl trinitrate; nitroglycerol; NTG<br />

Trade names:<br />

Buccal tablets<br />

Lingual aerosol: Nitrolingual (First Horizon)<br />

Oral capsules: Nitrocap; Nitrocine; Nitroglyn; Nitrospan<br />

Oral tablets: Klavikordal; Niong; Nitronet; Nitrong<br />

Parenteral: Nitro-Bid; Nitroject; Nitrol; Nitrostat (Pfizer);<br />

Tridil<br />

Sublingual tablets: Nitrostat (Pfizer)<br />

Topical ointment: Nitrol; Nitrong; Nitrostat (Pfizer)<br />

Topical transdermal systems: Deponit; Minitran (3M);<br />

Nitrocine; Nitrodisc; Nitrodur; Transderm-Nitro (Various<br />

pharmaceutical companies.)<br />

Indications: Acute angina<br />

Category: Nitrate; Vasodilator<br />

Half-life: 1–4 minutes<br />

Clinically important, potentially hazardous interactions<br />

with: acetylcysteine, alteplase, sildenafil<br />

Reactions<br />

NITROGLYCERIN 397<br />

Skin<br />

Allergic reactions (sic) (

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