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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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NEVIRAPINE<br />

Trade name: Viramune (Boehringer Ingelheim)<br />

Indications: HIV infections<br />

Category: Antiretroviral; Non-nucleoside reverse transcriptase<br />

inhibitor<br />

Half-life: 45 hours<br />

Clinically important, potentially hazardous interactions<br />

with: ketoconazole, midazolam, St John’s wort<br />

Reactions<br />

Skin<br />

Adverse effects (sic)<br />

(2001): MMWR 49, 1153<br />

Exanthems<br />

(2005): Pitche P+, Ann Dermatol Venereol 132(12 Pt 1), 970<br />

(2000): Barreiro P+, AIDS 14(14), 2153<br />

(2000): Palacios Munoz R+, Rev Clin Esp (Spanish) 200(11), 635<br />

Pruritus<br />

Rash (sic) (

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