Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Reactions Skin Erythema multiforme Pruritus (13%) (2004): Young TM+, Ann Pharmacother 38(11), 1868 (1998): McClellan KJ+, Drugs Aging 12(1), 76 (1993): Jankovic J+, Am J Med 95(1), 38 (scalp) (13.5%) Rash (sic) (2.4%) Xerosis (2%) Mucosal Aphthous stomatitis Xerostomia (1–10%) Hair Hair – pili torti (1998): McClellan KJ+, Drugs Aging 12(1), 76 (1989): McTavish D+, Drugs 38(5), 757 Other Chills (5%) Pain (5%) MIFEPRISTONE Synonym: RU-486 Trade name: Mifeprex (Danco) Indications: Medical termination of intrauterine pregnancy Category: Corticosteroid antagonist; Progestogen antagonist Half-life: ~20 hours Reactions Mucosal Vaginitis (3%) Other Abdominal pain (89%) (2003): Piaggio G+, Contraception 68(6), 439 (2002): Tang OS+, Hum Reprod 17(7), 1738 (89%) (with misoprostol) Chills (3–38%) (2002): Tang OS+, Hum Reprod 17(7), 1738 (38%) (with misoprostol) Fever (79%) (2002): Tang OS+, Hum Reprod 17(7), 1738 (79%) (with misoprostol) Infections (2001): DeHart RM+, Ann Pharmacother 35(6), 707 MIGLITOL Trade name: Glyset (Pfizer) Indications: Non-insulin dependent diabetes type ll Category: Alpha-glucosidase inhibitor Half-life: ~2 hours Skin Rash (sic) (1–10%) Reactions Other Abdominal pain (2002): Drent ML+, Diabetes Nutr Metab 15(3), 152 (2000): Campbell LK+, Ann Pharmacother 34(11), 1291 (2000): Scott LJ+, Drugs 59(3), 521 MIGLUSTAT Trade name: Zavesca (Actelion) Indications: Gaucher’s disease Category: Glucosylceramide synthase inhibitor Half-life: 6–7 hours Reactions Skin Burning (hands & feet) Mucosal Xerostomia (8%) Other Abdominal pain (50%) Neurotoxicity (2005): Prescrire Int 14(79), 168 (19%) MILK THISTLE* Scientific names: Carduus marainum; Silibum marianum Family: Asteraceae; Compositae Trade and other common names: Holy Thistle; Lady’s Thistle; Marian Thistle; Mary Thistle; Silymarin Category: Immunomodulator Purported indications and other uses: Dyspepsia, liver protectant, hepatitis, loss of appetite, spleen diseases, supportive treatment for mushroom poisoning Half-life: N/A Reactions Skin Adverse effects (sic) (2000): Evid Rep Technol p(21), 1 (1999): No Author, Med J Aust 170(5), 218 Allergic reactions (sic) Diaphoresis Rash (sic) (2001): Saller R+, Drugs 61(14), 2035 Urticaria (1990): Mironets VI+, Vrach Delo 7, 86 *Note: Seed as opposed to the ‘aboveground parts’ MILK THISTLE 367
368 MINOCYCLINE MINOCYCLINE Trade names: Alti-Minocycline; Apo-Minocycline; Arestin; Dynacin (Medicis); Mestacine; Minocin (Wyeth); Minoclir 50; Minogalen; Minomycin; Mynocine; Solodyn (Medicis); Syn- Minocycline Indications: Various infections caused by susceptible organisms Category: Antibiotic, tetracycline; Disease-modifying antirheumatic Half-life: 11–23 hours Clinically important, potentially hazardous interactions with: acitretin, aluminum salts, amoxicillin, ampicillin, antacids, bacampicillin, bismuth, calcium, carbenicillin, cloxacillin, digoxin, iron salts, isotretinoin, magnesium salts, methotrexate, methoxyflurane, mezlocillin, nafcillin, oxacillin, penicillins, piperacillin, ticarcillin, vitamin A, zinc, zinc salts Reactions Skin Acute febrile neutrophilic dermatosis (Sweet’s syndrome) (2002): Khan Durani+, Br J Dermatol 147(3), 558 (1992): Thibault M-J+, JAmAcadDermatol27, 801 (1991): Mensing H+, Dermatologica 182, 43 Acute generalized exanthematous pustulosis (AGEP) (1997): Yamamoto T+, Acta Derm Venereol (Stockh) 77, 168 (in a patient with pustular psoriasis) Angioedema (1997): Shapiro LE+, Arch Dermatol 133, 1224 (1994): Levy SB, Chapel Hill, NC (reproducible) (personal case) (observation) (1993): Litt JZ, Beachwood, OH (personal case) (observation) Cellulitis (1994): Kaufmann D+, Arch Intern Med 154, 1983 (1989): Andreano JM+, JAmAcadDermatol20, 934 Elastolysis (2000): Ho NC+, Am J Med 109(4), 340 Eosinophilic pustular folliculitis (Ofuji’s disease) (1989): Andreano JM+, JAmAcadDermatol20, 934 Erythema multiforme (2003): Bamberg C+, Hautarzt 54(9), 864 (1987): Shoji A+, Arch Dermatol 123, 18 Erythema nodosum (1990): Bridges AJ+, JAmAcadDermatol22, 959 Erythroderma (2002): Murray C+, World Congress Dermatol Poster, 0120 Exanthems (2002): Blumenthal HL, Beachwood, OH (personal case) (observation) (1996): Knowles SR+, Arch Dermatol 132, 934 (1995): Karofsky PS+, Arch Pediatr Adolesc Med 149, 217 (1995): Litt JZ, Beachwood, OH (2 personal cases, mother and daughter) (observation) (1994): Kaufmann D+, Arch Intern Med 154, 1983 Exfoliative dermatitis (
Page 1:
Litt’s Drug Eruption rEfErEncE Ma
Page 6 and 7:
CONTENTS Introduction vii Index of
Page 8 and 9:
INTRODUCTION Any drug can cause any
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A plus sign (+) after the authors n
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INDEX OF GENERIC AND TRADE NAMES Ad
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INDEX OF GENERIC AND TRADE NAMES am
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INDEX OF GENERIC AND TRADE NAMES as
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INDEX OF GENERIC AND TRADE NAMES Be
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INDEX OF GENERIC AND TRADE NAMES ca
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INDEX OF GENERIC AND TRADE NAMES ci
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INDEX OF GENERIC AND TRADE NAMES Cy
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INDEX OF GENERIC AND TRADE NAMES Di
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INDEX OF GENERIC AND TRADE NAMES Du
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INDEX OF GENERIC AND TRADE NAMES Et
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INDEX OF GENERIC AND TRADE NAMES FU
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INDEX OF GENERIC AND TRADE NAMES Hi
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INDEX OF GENERIC AND TRADE NAMES Is
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INDEX OF GENERIC AND TRADE NAMES Le
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INDEX OF GENERIC AND TRADE NAMES Me
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INDEX OF GENERIC AND TRADE NAMES Mo
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INDEX OF GENERIC AND TRADE NAMES Ni
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INDEX OF GENERIC AND TRADE NAMES Op
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INDEX OF GENERIC AND TRADE NAMES pe
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INDEX OF GENERIC AND TRADE NAMES Pr
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INDEX OF GENERIC AND TRADE NAMES Re
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INDEX OF GENERIC AND TRADE NAMES Si
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INDEX OF GENERIC AND TRADE NAMES Sy
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INDEX OF GENERIC AND TRADE NAMES to
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INDEX OF GENERIC AND TRADE NAMES Ur
Page 63 and 64:
INDEX OF GENERIC AND TRADE NAMES Xo
Page 65 and 66:
INDEX OF HERBALS Cola acuminata caf
Page 67 and 68:
INDEX OF HERBS Smilax regelii sarsa
Page 69 and 70:
MAIN CLASSES OF DRUGS ACE inhibitor
Page 71 and 72:
Antiplatelet abciximab aspirin cilo
Page 73 and 74:
MAIN CLASSES OF DRUGS Histamine H1
Page 76 and 77:
ABACAVIR Trade names: Trizivir (GSK
Page 78 and 79:
Xerostomia (2%) Hair Hair - alopeci
Page 80 and 81:
(2006): Santoro D+, Clin Nephrol 66
Page 82 and 83:
Exanthems (2-25%) (1999): Katz HI+,
Page 84 and 85:
ADALIMUMAB Synonym: D2E7 Trade name
Page 86 and 87:
ALBENDAZOLE Trade names: ABZ; Alben
Page 88 and 89:
(2003): Chodorowska G+, Ann Univ Ma
Page 90 and 91:
ALFENTANIL Trade names: Alfenta (Ak
Page 92 and 93:
Lupus erythematosus (1980): Condemi
Page 94 and 95:
Other Abdominal pain (2005): Turgeo
Page 96 and 97:
(1982): van Ketel WG, Contact Derma
Page 98 and 99:
Exanthems Photosensitivity (1984):
Page 100 and 101:
(1980): Lawyer CH+, J Allergy Clin
Page 102 and 103:
Purpura (2%) (1983): Fogoros RN+, C
Page 104 and 105:
(2006): Piller LB+, J Clin Hyperten
Page 106 and 107:
(2006): Gonzalez-Delgado P+, Allerg
Page 108 and 109:
Chills (2004): Martino R, Curr Med
Page 110 and 111:
AMPRENAVIR* Trade name: Agenerase (
Page 112 and 113:
(2001): Ahrendt DM, Am Fam Physicia
Page 114 and 115:
(1999): Ellenberg SS, Center for Bi
Page 116 and 117:
(1996): Martinelli L+, Ann Thorac S
Page 118 and 119:
(2003): Uede K+, Br J Dermatol 149(
Page 120 and 121:
ARTEMISIA Scientific names: Artemis
Page 122 and 123:
ASPIRIN Synonyms: acetylsalicylic a
Page 124 and 125:
ATAZANAVIR Trade name: Reyataz (Bri
Page 126 and 127:
(1999): Oakley A, Hamilton, New Zea
Page 128 and 129:
(2002): Robenshtok E+, Isr Med Asso
Page 130 and 131:
Scleroderma (1993): Choy E+, Br J R
Page 132 and 133:
(1997): Epstein ME+, JAmAcadDermato
Page 134 and 135:
Hair Hair - hypertrichosis (3-10%)
Page 136 and 137:
(1997): Banac S+, Acta Paediatr 86(
Page 138 and 139:
BENZALKONIUM Synonyms: parasterol;
Page 140 and 141:
(2002): Gruson LM+, Arch Pediatr Ad
Page 142 and 143:
(2000): Bedikian AY+, Oncol Rep 7,
Page 144 and 145:
BISMUTH Trade names: Bismatrol; Bis
Page 146 and 147:
BLEOMYCIN Synonyms: bleo; BLM Trade
Page 148 and 149:
BLOODROOT Scientific name: Sanguina
Page 150 and 151:
Punctate keratitis (2004): Northing
Page 152 and 153:
BROMFENAC Trade name: Xibrom (ISTA
Page 154 and 155:
Erythema multiforme (
Page 156 and 157:
Myalgia/Myositis/Myopathy/Myotoxici
Page 158 and 159:
(1989): Ackerman WE+, Can J Anaesth
Page 160 and 161:
CALFACTANT Trade name: Infasurf (Fo
Page 162 and 163:
CAPSICUM Scientific names: Capsicum
Page 164 and 165:
Lupus erythematosus (2002): Ratliff
Page 166 and 167:
Corneal edema Eyelid twitching Kera
Page 168 and 169:
Stevens-Johnson syndrome (1-10%) (2
Page 170 and 171:
Porphyria variegata (2001): Grieco
Page 172 and 173:
(1983): Rollings HE+, Curr Ther Res
Page 174 and 175:
Dermatitis (1986): Hirata M+, Kokyu
Page 176 and 177:
Other Anaphylactoid reactions/Anaph
Page 178 and 179:
Page 180 and 181:
Page 182 and 183:
Candidiasis (
Page 184 and 185:
Herpes zoster (
Page 186 and 187:
Hypersensitivity Injection-site pai
Page 188 and 189:
Other Abdominal pain (25%) Anaphyla
Page 190 and 191:
CHLORAMBUCIL Trade names: Chloramin
Page 192 and 193:
(1992): Ramselaar CG+, Br J Urol 70
Page 194 and 195:
(1997): Selvaag E, Ann Trop Pediatr
Page 196 and 197:
(1989): Rosen C, Semin Dermatol 8,
Page 198 and 199:
CHOLESTYRAMINE Trade names: Chol-Le
Page 200 and 201:
CIMETIDINE Trade names: Apo-Cimetid
Page 202 and 203:
(2000): Sharobeem KM+, J Cardiovasc
Page 204 and 205:
(1997): Carrasco JM+, Ann Pharmacot
Page 206 and 207:
CITALOPRAM Synonym: nitalapram Trad
Page 208 and 209:
CLEMASTINE Trade names: Aller-Eze;
Page 210 and 211:
Other Hypersensitivity (2002): Somm
Page 212 and 213:
CLOMIPRAMINE Trade names: Anafranil
Page 214 and 215:
CLOPIDOGREL Trade name: Plavix (Bri
Page 216 and 217:
Eczema (
Page 218 and 219:
(1997): Thaler D, Monona, WI (from
Page 220 and 221:
COCOA Scientific names: Theobroma c
Page 222 and 223:
COLESEVELAM Trade name: Welchol (Sa
Page 224 and 225:
CORDYCEPS Scientific name: Cordycep
Page 226 and 227:
CYCLAMATE Trade name: Sucaryl (Abbo
Page 228 and 229:
Inappropriate secretion of antidiur
Page 230 and 231:
(1996): Cox NH, Clin Exp Dermatol 2
Page 232 and 233:
(2007): Lim AK+, Intern Med J 37(1)
Page 234 and 235:
(1989): Kerker BJ+, Semin Dermatol
Page 236 and 237:
Pruritus (1-10%) Rash (sic) (1-10%)
Page 238 and 239:
(1988): Tham SN+, Singapore Med J 2
Page 240 and 241:
DASATINIB Synonym: BMS354825 Trade
Page 242 and 243:
Page 244 and 245:
(1980): Miescher PA+, Clin Haematol
Page 246 and 247:
(1985): Job JC+, Arch Fr Pediatr 42
Page 248 and 249:
DEXTROMETHORPHAN Trade names: Balmi
Page 250 and 251:
Erythema nodosum (
Page 252 and 253:
Mucosal Oral ulceration Hair Hair -
Page 254 and 255:
(1987): Masden JJ+, Curr Ther Res 4
Page 256 and 257:
(1998): Knowles S+, JAmAcadDermatol
Page 258 and 259:
Epiphora Other Abdominal pain Fever
Page 260 and 261:
DISOPYRAMIDE Trade names: Dimodan;
Page 262 and 263:
(1995): Cortes JE+, J Clin Oncol 13
Page 264 and 265:
DOMPERIDONE Trade names: Evoxin; Mo
Page 266 and 267:
DOXAPRAM Trade name: Dopram (Baxter
Page 268 and 269:
(1989): Jones AP+, Br J Cancer 59,
Page 270 and 271:
(1992): Bennett MJ, JRArmyMedCorps1
Page 272 and 273:
ECHINACEA Scientific names: Echinac
Page 274 and 275:
Hot flashes (
Page 276 and 277:
Pemphigus vegetans (1994): Bastiaen
Page 278 and 279:
Stevens-Johnson syndrome (
Page 280 and 281:
Ocular pruritus (1-10%) Other Cough
Page 282 and 283:
(2002): Bohm M+, Drug Saf 25(8), 59
Page 284 and 285:
Pustules (1993): Manu Shah R+, Eur
Page 286 and 287:
ESTAZOLAM Trade names: Domnamid; Es
Page 288 and 289:
Allergic reactions (sic) Cellulitis
Page 290 and 291:
Exanthems Photosensitivity Purpura
Page 292 and 293:
Other Anticonvulsant hypersensitivi
Page 294 and 295:
ETORICOXIB Trade names: Algix; Arco
Page 296 and 297:
Purpura (1996): Kallal SM+, West J
Page 298 and 299:
(1980): Couzigou P+, Therapie 35(3)
Page 300 and 301:
FINASTERIDE Trade names: Pro-Cure;
Page 302 and 303:
(1991): Abbott M+, Lancet 2, 633 Bu
Page 304 and 305:
FLUOCINOLONE Trade names: Capex (Ga
Page 306 and 307:
(2003): Salim A+, Br J Dermatol 148
Page 308 and 309:
Erythema multiforme (1985): Wernick
Page 310 and 311:
Injection-site reactions Rhabdomyol
Page 312 and 313:
Toxic epidermal necrolysis Urticari
Page 314 and 315:
Reactions Skin Angioedema Erythema
Page 316 and 317:
Reactions Skin Acne (
Page 318 and 319:
Thrombophlebitis *Note: Furosemide
Page 320 and 321:
GANCICLOVIR Trade names: Cymevan; C
Page 322 and 323:
(2002): Baselga J+, J Clin Oncol 20
Page 324 and 325:
(2003): D’Alessandro V+, Clin Ter
Page 326 and 327:
(1996): Merlob P+, Cutis 57, 429 (n
Page 328 and 329:
Hair Hair - alopecia (>2%) Nails Na
Page 330 and 331:
GLYBURIDE Synonyms: glibenclamide;
Page 332 and 333:
(1982): Bailin PL+, Clin Rheum Dis
Page 334 and 335:
Acne (1996): Lee PK+, JAmAcadDermat
Page 336 and 337:
(2006): Bonkovsky HL, AnnInternMed1
Page 338 and 339:
Peripheral edema (>10%) Purpura Urt
Page 340 and 341:
(1984): Binder RL+, J Clin Psychiat
Page 342 and 343:
HEPARIN Trade names: Calcilean; Cal
Page 344 and 345:
(1990): Rogerson SJ+, BMJ 301, 345
Page 346 and 347:
(1991): Vitris M+, Dakar Med 36(1),
Page 348 and 349:
Page 350 and 351:
Exanthems Exfoliative dermatitis Fi
Page 352 and 353:
HYDROMORPHONE Trade names: Dilaudid
Page 354 and 355:
(1994): Perrot JL+, Ann Dermatol Ve
Page 356 and 357:
Edema (
Page 358 and 359:
(1994): Halpern SM, Arch Dermatol 1
Page 360 and 361:
Mucosal Oral lesions Sialorrhea (
Page 362 and 363:
IMIGLUCERASE Trade name: Cerezyme (
Page 364 and 365:
(2001): Fife KH+, Sex Transm Dis 28
Page 366 and 367:
Herpes simplex (
Page 368 and 369:
(2004): Scheinfeld N, J Drugs Derma
Page 370 and 371:
(2000): Poole PJ+, Cochrane Databas
Page 372 and 373:
Injection-site pain (2006): Moyes V
Page 374 and 375:
(2002): Tothova E+, Neoplasma 49(2)
Page 376 and 377:
(1995): Shinohara K, NEnglJMed333,
Page 378 and 379:
IOPROMIDE Trade name: Ultravist (Be
Page 380 and 381:
ISOCARBOXAZID Trade names: Enerzer;
Page 382 and 383:
ISOSORBIDE Trade name: Ismotic Indi
Page 384 and 385:
Nails Nails - brittle (2001): Önde
Page 386 and 387:
Serum sickness (1998): Park H+, Ann
Page 388 and 389:
(2001): Burstal R+, Anaesth Intensi
Page 390 and 391:
Pruritus (1-10%) Psoriasis (1992):
Page 392 and 393: LAMIVUDINE Synonym: 3TC Trade names
Page 394 and 395: (2006): Fix OK+, Clin Gastroenterol
Page 396 and 397: Eyelashes - ptosis (2005): Casson R
Page 398 and 399: LETROZOLE Trade name: Femara (Novar
Page 400 and 401: Other Abdominal pain (2003): Cramer
Page 402 and 403: Photosensitivity (
Page 404 and 405: (2002): Kalin JR+, JForensicSci47(5
Page 406 and 407: (2002): Serratrice J+, Am J Ophthal
Page 408 and 409: (1981): Hess EV, Arthritis Rheum 24
Page 410 and 411: Purpura (
Page 412 and 413: Reactions Skin Angioedema (
Page 414 and 415: Other Abdominal pain (7%) Cough (1%
Page 416 and 417: Reactions Skin Acne (1998): Wollina
Page 418 and 419: (1983): Nusbaum BP+, Arch Dermatol
Page 420 and 421: (1997): O’Reilly FM+, American Ac
Page 422 and 423: MEMANTINE Trade names: Akatinol; Ax
Page 424 and 425: MERCAPTOPURINE Synonyms: 6-mercapto
Page 426 and 427: (1998): Leal G, Fortaleza, Brazil (
Page 428 and 429: (2002): Caplehorn JR+, Aust N Z J P
Page 430 and 431: (1995): Vogt T+, Br J Dermatol 133,
Page 432 and 433: Mucosal Aphthous stomatitis (2003):
Page 434 and 435: (1987): Norris PG+, Clin Exp Dermat
Page 436 and 437: (1998): Corazza M+, Contact Dermati
Page 438 and 439: METOCLOPRAMIDE Trade names: Apo-Met
Page 440 and 441: Oral ulceration Stomatitis (1987):
Page 444 and 445: (1996): Carrington PR, Little Rock,
Page 446 and 447: (2003): Abe M+, Intern Med 42(1), 4
Page 448 and 449: Other Abdominal pain (2006): Preutt
Page 450 and 451: Erythema multiforme Exanthems (9-16
Page 452 and 453: Other Anaphylactoid reactions/Anaph
Page 454 and 455: MUPIROCIN* Trade names: Bactoderm;
Page 456 and 457: Mucosal Gingivitis (
Page 458 and 459: (1981): Wolf A, ZHautkr(German) 56,
Page 460 and 461: (1984): Stern RS+, JAMA 252, 1433 V
Page 462 and 463: Hair Hair - alopecia (
Page 464 and 465: NEVIRAPINE Trade name: Viramune (Bo
Page 466 and 467: (1982): Grunwald Z, Drug Intell Cli
Page 468 and 469: Urticaria (
Page 470 and 471: (2000): Rodrigues de Oliveira J+, G
Page 472 and 473: (2007): Koulaouzidis A+, Ann Hepato
Page 474 and 475: Vulvovaginal candidiasis (2002): Me
Page 476 and 477: Mucosal Oral mucosal eruption (1987
Page 478 and 479: Mucosal Tongue edema Other Anaphyla
Page 480 and 481: Chills (5-10%) Hypersensitivity (
Page 482 and 483: OXACILLIN Trade names: Bactocill; B
Page 484 and 485: Other Anaphylactoid reactions/Anaph
Page 486 and 487: OXYMORPHONE Synonym: 14-hydroxy-dih
Page 488 and 489: (2001): Robinson JB+, Gynecol Oncol
Page 490 and 491: PANCRELIPASE Trade names: Cotazym (
Page 492 and 493:
Exanthems Fixed eruption (1994): Ki
Page 494 and 495:
(2006): Bettoli V+, Acta Derm Vener
Page 496 and 497:
Reactions Skin Adverse effects (sic
Page 498 and 499:
(1981): Hashimoto K+, JAmAcadDermat
Page 500 and 501:
Hypersensitivity (1999): Hsu HL+, T
Page 502 and 503:
Injection-site calcification (1991)
Page 504 and 505:
PEPPERMINT Scientific name: Mentha
Page 506 and 507:
(1995): Magro CM+, JAmAcadDermatol3
Page 508 and 509:
(1993): Leenutaphong V+, Int J Derm
Page 510 and 511:
PHENYLEPHRINE Trade names: Dionephr
Page 512 and 513:
(1991): Kleier RS, Arch Dermatol 12
Page 514 and 515:
Lymphoproliferative disease (1992):
Page 516 and 517:
(2006): Andersen KE+, Contact Derma
Page 518 and 519:
Oral candidiasis Stomatodynia Vagin
Page 520 and 521:
Reactions Skin Exanthems Petechiae
Page 522 and 523:
Reactions Skin Acne (1-10%) Angioed
Page 524 and 525:
Pruritus (
Page 526 and 527:
PREDNISONE Trade names: Deltasone (
Page 528 and 529:
Other Anticonvulsant hypersensitivi
Page 530 and 531:
Xerosis Mucosal Lip ulceration (198
Page 532 and 533:
(1982): Gall H+, Derm Beruf Umwelt
Page 534 and 535:
(2006): Barkin RL+, Am J Ther 13(6)
Page 536 and 537:
PROTAMINE SULFATE Indications: Hepa
Page 538 and 539:
(1987): Shelley WB+, JAmAcadDermato
Page 540 and 541:
Hypersensitivity Myalgia/Myositis/M
Page 542 and 543:
(1999): Drayton G, Los Angeles, CA
Page 544 and 545:
(1986): Bigby M+, JAMA 256, 3358 (1
Page 546 and 547:
Nails Nails - photo-onycholysis (19
Page 548 and 549:
Hair Hair - alopecia (1-10%) Other
Page 550 and 551:
RASBURICASE Trade names: Elitek (Sa
Page 552 and 553:
RETEPLASE Synonyms: recombinant pla
Page 554 and 555:
Other Inappropriate secretion of an
Page 556 and 557:
Tongue pigmentation Vulvovaginal ca
Page 558 and 559:
Reactions Skin Acne (
Page 560 and 561:
RIZATRIPTAN Synonym: MK462 Trade na
Page 562 and 563:
Glossitis (1%) Stomatitis (
Page 564 and 565:
(1995): Brandstatter G+, Clin Ther
Page 566 and 567:
Mucosal Cheilitis (
Page 568 and 569:
SELENIUM Trade names: Bio-Active Se
Page 570 and 571:
Mucosal Aphthous stomatitis (
Page 572 and 573:
(2004): Vasconcelos OM+, Muscle Ner
Page 574 and 575:
(2005): Mahe E+, Transplantation 79
Page 576 and 577:
SOLIFENACIN Trade name: Vesicare (G
Page 578 and 579:
Urticaria (
Page 580 and 581:
Pruritus (1997): Golsch S+, Hautarz
Page 582 and 583:
Glossitis (2%) Oral mucosal eruptio
Page 584 and 585:
Reactions Skin Allergic reactions (
Page 586 and 587:
(1995): Hertl M+, Br J Dermatol 132
Page 588 and 589:
(1992): Bodokh I+, Presse Med (Fren
Page 590 and 591:
SULFISOXAZOLE* Trade names: Isoxazi
Page 592 and 593:
(1984): Stern RS+, JAMA 252, 1433 J
Page 594 and 595:
TACROLIMUS Synonym: FK506 Trade nam
Page 596 and 597:
(2005): Fumal I+, Dermatology 210(3
Page 598 and 599:
(2000): Ernst E+, Forsch Komplement
Page 600 and 601:
Page 602 and 603:
Reactions Skin Diaphoresis (>1%) Ed
Page 604 and 605:
Mucosal Oral ulceration (1987): Hig
Page 606 and 607:
TETRACYCLINE Trade names: Apo-Tetra
Page 608 and 609:
Xerosis (2002): Bariol C+, J Gastro
Page 610 and 611:
Eyes Conjunctivitis (allergic conta
Page 612 and 613:
Page 614 and 615:
(2000): Chemnitz JM+, Med Klin (Ger
Page 616 and 617:
Note: Cutaneous side-effects of bet
Page 618 and 619:
Other Cough (0.8%) Fever (4.6%) Hep
Page 620 and 621:
TOLAZAMIDE* Trade names: Diabewas;
Page 622 and 623:
Reactions Skin Erythema (1.9%) Fung
Page 624 and 625:
TOSITUMOMAB & IODINE 131 Trade name
Page 626 and 627:
(2001): Vogel CL+, Oncology 61, 37
Page 628 and 629:
(1997): Gilchrest BA, JAmAcadDermat
Page 630 and 631:
Erythema (1999): Alexiou C+, Laryng
Page 632 and 633:
*Note: Trichlormethiazide is a sulf
Page 634 and 635:
TRIMETHOPRIM* Trade names: Abaprim;
Page 636 and 637:
Myalgia/Myositis/Myopathy/Myotoxici
Page 638 and 639:
Other Death (2002): Avarello TP+, N
Page 640 and 641:
(2001): Pechlaner C+, Blood Coagul
Page 642 and 643:
Bullous dermatitis (2001): Christ E
Page 644 and 645:
(1985): Schifter S+, Lancet 2, 499
Page 646 and 647:
Page 648 and 649:
VERAPAMIL Trade names: APO-Verap; A
Page 650 and 651:
Mucosal Gingival hyperplasia/hypert
Page 652 and 653:
(2001): Laack E+, Ann Oncol 12(12),
Page 654 and 655:
Fixed eruption (
Page 656 and 657:
(1986): Sjoberg A+, Lakartidningen
Page 658 and 659:
(1990): Broder S+, Am J Med 88, 31S
Page 660 and 661:
(1989): Valencia ME+, Rev Clin Esp
Page 662 and 663:
ZOLPIDEM Trade names: Ambien (Sanof
Page 664 and 665:
DRUGS RESPONSIBLE FOR COMMON REACTI
Page 666 and 667:
Ethambutol Ethanolamine Etoposide F
Page 668 and 669:
Procarbazine Progestins Promethazin
Page 670 and 671:
Erlotinib Ertapenem Escitalopram Et
Page 672 and 673:
Feverfew Floxuridine Fluconazole Fl
Page 674 and 675:
Insulin glulisine Interferon alfa I
Page 676 and 677:
Acamprosate Acebutolol Acetaminophe
Page 678 and 679:
Amobarbital Amoxicillin Amphoterici
Page 680 and 681:
Spironolactone Streptomycin Sulface
Page 682 and 683:
Miconazole Midazolam Minocycline Mi
Page 684 and 685:
Heroin Hydralazine Hydrochlorothiaz
Page 686 and 687:
Nefazodone Nevirapine Niacin Nicoti
Page 688 and 689:
Mephenytoin Mercaptopurine Mesalami
Page 690 and 691:
Cephradine Cetuximab Chamomile Chlo
Page 692 and 693:
Oxaprozin Penicillin G Phenytoin Pi
Page 694 and 695:
Ritonavir Rofecoxib Saquinavir Sele
Page 696 and 697:
Chlorotrianisene Chlorpheniramine C
Page 698 and 699:
Timolol Tinidazole Tolcapone Topira
Page 700 and 701:
Maprotiline Marihuana Mebendazole M
Page 702 and 703:
Allopurinol Alprazolam Alteplase Am
Page 704 and 705:
Azatadine Azathioprine Azithromycin
Page 706 and 707:
Phenelzine Phenindamine Phenobarbit
Page 708 and 709:
Seborrheic Dermatitis Buspirone Chl
Page 710 and 711:
Dacarbazine Dactinomycin Daptomycin
Page 712 and 713:
Anagrelide Anidulafungin Anisindion
Page 714 and 715:
Rifampin Rifapentine Rifaximin Rise
Page 716 and 717:
Tretinoin Valdecoxib Varicella vacc
Page 718:
Prazosin Pregabalin Procarbazine Pr
Page 721 and 722:
646 DESCRIPTION OF THE 34 MOST COMM
Page 723 and 724:
Page 725 and 726:
Page 728 and 729:
ALPHABETICAL INDEX Abacavir 1 Abare
Page 730 and 731:
Hawthorn (fruit, leaf, flower extra
Page 732 and 733:
Tirofiban 543 Tixocortol 543 Tizani
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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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