Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
(2002): Kalin JR+, JForensicSci47(5), 1135 (overdose) (2002): Nisse P+, Acta Clin Belg Suppl 1, 51 Embolia cutis medicamentosa (Nicolau syndrome) (1990): Wand A+, Aktuel Dermatol (German) 16, 128 Hypersensitivity (2006): Hickey JR+, Contact Dermatitis 54(4), 215 (2003): Mackley CL+, Arch Dermatol 139(3), 343 (1998): Marks JG+, JAmAcadDermatol38(6), 911 (1996): Bircher AJ+, Contact Dermatitis 34, 387 (1996): Whalen JD+, Arch Dermatol 132, 1256 (1991): Klein CE+, Contact Dermatitis 25(1), 45 Injection-site pain Injection-site phlebitis LINCOMYCIN Trade names: Albiotic; Cillimicina; Cillimycin; Lincocin (Pfizer); Lincocine; Princol; Zumalin Indications: Various infections caused by susceptible organisms Category: Antibiotic, lincosamide Half-life: 2–11.5 hours Reactions Skin Acute generalized exanthematous pustulosis (2005): Otsuka A+, JDermatol32(11), 929 (2003): Valois M+, Contact Dermatitis 48(3), 169 Allergic reactions (sic) (1–5%) Angioedema Dermatitis (1991): Vilaplana J+, Contact Dermatitis 24, 225 (1985): Conde-Salazar L+, Contact Dermatitis 12, 59 (erythema multiforme-like) Erythema multiforme Exanthems Exfoliative dermatitis Photosensitivity Pruritus Pruritus ani et vulvae (
330 LINDANE (1989): Vercel M+, Cah Anesthesiol 37(7), 543 (1988): Sunder Ram Rao CV+, Vet Hum Toxicol 30(2), 132 (1985): American Hospital Formulary Service-Drug Information 85, 1601 (1984): Gosselin RE+, Clinical Toxicology of Commercial Products 5th ed, III–239 (1983): Davies JE+, Arch Dermatol 119(2), 142 (1982): Telch J+, Can Med Assoc 126(6), 662 (1982): Telch J+, Can Med Assoc 127(9), 821 (1980): Powell GM, Cent Afr J Med 26(7), 170 (1980): Rasmussen JE, Arch Dermatol 116(11), 1226 Neurotoxicity (2006): Prescrire Int 15(82), 61 (2006): Singal A+, Am J Ther 13(3), 277 Rhabdomyolysis (1988): Sunder Ram Rao CV+, Vet Hum Toxicol 30(2), 132 (1984): Jaeger U+, Vet Hum Toxicol 26(1), 11 LINEZOLID Trade name: Zyvox (Pfizer) Indications: Various infections caused by susceptible organisms Category: Antibiotic, oxazolidinone Half-life: 4–5 hours Clinically important, potentially hazardous interactions with: amitriptyline, amoxapine, clomipramine, desipramine, dextromethorphan, doxepin, fluoxetine, fluvoxamine, imipramine, meperidine, nortriptyline, paroxetine, protriptyline, sertraline, sibutramine, trazodone, tricyclic antidepressants, trimipramine, venlafaxine Reactions Skin Adverse effects (sic) (4%) (2003): Birmingham MC+, Clin Infect Dis 36(2), 159 (4%) Allergic reactions (sic) (4%) (2003): Birmingham MC+, Clin Infect Dis 36(2), 159 (4%) Exanthems (2006): Borras-Blasco J+, Int J Clin Pharmacol Ther 44(7), 331 (generalized) Fungal dermatitis (0.1–2%) Pruritus Rash (sic) (2%) (2005): Aneziokoro CO+, JChemother17(6), 643 (5%) Mucosal Candidal vaginitis (1–2%) Oral candidiasis (
- Page 354 and 355: (1994): Perrot JL+, Ann Dermatol Ve
- Page 356 and 357: Edema (
- Page 358 and 359: (1994): Halpern SM, Arch Dermatol 1
- Page 360 and 361: Mucosal Oral lesions Sialorrhea (
- Page 362 and 363: IMIGLUCERASE Trade name: Cerezyme (
- Page 364 and 365: (2001): Fife KH+, Sex Transm Dis 28
- Page 366 and 367: Herpes simplex (
- Page 368 and 369: (2004): Scheinfeld N, J Drugs Derma
- Page 370 and 371: (2000): Poole PJ+, Cochrane Databas
- Page 372 and 373: Injection-site pain (2006): Moyes V
- Page 374 and 375: (2002): Tothova E+, Neoplasma 49(2)
- Page 376 and 377: (1995): Shinohara K, NEnglJMed333,
- Page 378 and 379: IOPROMIDE Trade name: Ultravist (Be
- Page 380 and 381: ISOCARBOXAZID Trade names: Enerzer;
- Page 382 and 383: ISOSORBIDE Trade name: Ismotic Indi
- Page 384 and 385: Nails Nails - brittle (2001): Önde
- Page 386 and 387: Serum sickness (1998): Park H+, Ann
- Page 388 and 389: (2001): Burstal R+, Anaesth Intensi
- Page 390 and 391: Pruritus (1-10%) Psoriasis (1992):
- Page 392 and 393: LAMIVUDINE Synonym: 3TC Trade names
- Page 394 and 395: (2006): Fix OK+, Clin Gastroenterol
- Page 396 and 397: Eyelashes - ptosis (2005): Casson R
- Page 398 and 399: LETROZOLE Trade name: Femara (Novar
- Page 400 and 401: Other Abdominal pain (2003): Cramer
- Page 402 and 403: Photosensitivity (
- Page 406 and 407: (2002): Serratrice J+, Am J Ophthal
- Page 408 and 409: (1981): Hess EV, Arthritis Rheum 24
- Page 410 and 411: Purpura (
- Page 412 and 413: Reactions Skin Angioedema (
- Page 414 and 415: Other Abdominal pain (7%) Cough (1%
- Page 416 and 417: Reactions Skin Acne (1998): Wollina
- Page 418 and 419: (1983): Nusbaum BP+, Arch Dermatol
- Page 420 and 421: (1997): O’Reilly FM+, American Ac
- Page 422 and 423: MEMANTINE Trade names: Akatinol; Ax
- Page 424 and 425: MERCAPTOPURINE Synonyms: 6-mercapto
- Page 426 and 427: (1998): Leal G, Fortaleza, Brazil (
- Page 428 and 429: (2002): Caplehorn JR+, Aust N Z J P
- Page 430 and 431: (1995): Vogt T+, Br J Dermatol 133,
- Page 432 and 433: Mucosal Aphthous stomatitis (2003):
- Page 434 and 435: (1987): Norris PG+, Clin Exp Dermat
- Page 436 and 437: (1998): Corazza M+, Contact Dermati
- Page 438 and 439: METOCLOPRAMIDE Trade names: Apo-Met
- Page 440 and 441: Oral ulceration Stomatitis (1987):
- Page 442 and 443: Reactions Skin Erythema multiforme
- Page 444 and 445: (1996): Carrington PR, Little Rock,
- Page 446 and 447: (2003): Abe M+, Intern Med 42(1), 4
- Page 448 and 449: Other Abdominal pain (2006): Preutt
- Page 450 and 451: Erythema multiforme Exanthems (9-16
- Page 452 and 453: Other Anaphylactoid reactions/Anaph
330 LINDANE<br />
(1989): Vercel M+, Cah Anesthesiol 37(7), 543<br />
(1988): Sunder Ram Rao CV+, Vet Hum Toxicol 30(2), 132<br />
(1985): American Hospital Formulary Service-<strong>Drug</strong> Information<br />
85, 1601<br />
(1984): Gosselin RE+, Clinical Toxicology of Commercial Products<br />
5th ed, III–239<br />
(1983): Davies JE+, Arch Dermatol 119(2), 142<br />
(1982): Telch J+, Can Med Assoc 126(6), 662<br />
(1982): Telch J+, Can Med Assoc 127(9), 821<br />
(1980): Powell GM, Cent Afr J Med 26(7), 170<br />
(1980): Rasmussen JE, Arch Dermatol 116(11), 1226<br />
Neurotoxicity<br />
(2006): Prescrire Int 15(82), 61<br />
(2006): Singal A+, Am J Ther 13(3), 277<br />
Rhabdomyolysis<br />
(1988): Sunder Ram Rao CV+, Vet Hum Toxicol 30(2), 132<br />
(1984): Jaeger U+, Vet Hum Toxicol 26(1), 11<br />
LINEZOLID<br />
Trade name: Zyvox (Pfizer)<br />
Indications: Various infections caused by susceptible organisms<br />
Category: Antibiotic, oxazolidinone<br />
Half-life: 4–5 hours<br />
Clinically important, potentially hazardous interactions<br />
with: amitriptyline, amoxapine, clomipramine, desipramine,<br />
dextromethorphan, doxepin, fluoxetine, fluvoxamine,<br />
imipramine, meperidine, nortriptyline, paroxetine, protriptyline,<br />
sertraline, sibutramine, trazodone, tricyclic antidepressants,<br />
trimipramine, venlafaxine<br />
Reactions<br />
Skin<br />
Adverse effects (sic) (4%)<br />
(2003): Birmingham MC+, Clin Infect Dis 36(2), 159 (4%)<br />
Allergic reactions (sic) (4%)<br />
(2003): Birmingham MC+, Clin Infect Dis 36(2), 159 (4%)<br />
Exanthems<br />
(2006): Borras-Blasco J+, Int J Clin Pharmacol Ther 44(7), 331<br />
(generalized)<br />
Fungal dermatitis (0.1–2%)<br />
Pruritus<br />
Rash (sic) (2%)<br />
(2005): Aneziokoro CO+, JChemother17(6), 643 (5%)<br />
Mucosal<br />
C<strong>and</strong>idal vaginitis (1–2%)<br />
Oral c<strong>and</strong>idiasis (