Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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(2001): Burstal R+, Anaesth Intensive Care 29(3), 246 (2001): Subramaniam K+, J Clin Anesth 13(5), 339 (with morphine) Rash (sic) (1–10%) Mucosal Sialorrhea (

314 KETOCONAZOLE Nails Nails – pigmentation (1985): Dreessen K, ZHautkr(German) 60, 679 (black longitudinal bands) Other Anaphylactoid reactions/Anaphylaxis (2005): Liu PY+, Ann Pharmacother 39(3), 547 (1994): Gupta AK+, JAmAcadDermatol30, 677 (passim) (1983): van Dijke CPH+, BMJ 287, 1673 Chills (1–3%) Death (2001): Duman D+, Am J Med 111(9), 737 (1994): Sella A+, J Clin Oncol 12(4), 683 (with doxorubicin) Gynecomastia (1–3%) (1994): Gupta AK+, JAmAcadDermatol30, 677 (passim) (1993): Thompson DF+, Pharmacotherapy 13, 37 (1982): Moncada B, JAmAcadDermatol7, 557 (1981): DeFelice R+, Antimicrob Agents Chemo 19, 1073 Hepatotoxicity (2007): Stein CA+, Invest New Drugs 25(3), 277 (with lovastatin) Hypersensitivity (1994): Gonzalez-Delgado P+, Ann Allergy 73, 326 (1992): Verschueren GL+, Contact Dermatitis 26, 47 (1989): Garcia-Bravo B+, Contact Dermatitis 21, 346 Myalgia/Myositis/Myopathy/Myotoxicity (1991): Garty BZ+, Am J Dis Child 145, 970 Rhabdomyolysis (2007): Akram K+, Int J Cardiol 118(1), e19 (with simvastatin) (2007): Stein CA+, Invest New Drugs 25(3), 277 (with lovastatin) (1999): Gilad R+, Clin Neuropharmacol 22(5), 295 (with simvastatin) KETOPROFEN Trade names: Alrheumat; Alrheumun; Aneol; Bi-Profenid; Gabrilen Retard; Keduril; Novo-Keto; Orudis (Sanofi-Aventis); Oruvail (Wyeth); Rhodis; Rhovail Indications: Arthritis Category: Non-steroidal anti-inflammatory Half-life: 1.5–4 hours Clinically important, potentially hazardous interactions with: aspirin, methotrexate, probenecid Reactions Skin Allergic reactions (sic) (

(2001): Burstal R+, Anaesth Intensive Care 29(3), 246<br />

(2001): Subramaniam K+, J Clin Anesth 13(5), 339 (with<br />

morphine)<br />

Rash (sic) (1–10%)<br />

Mucosal<br />

Sialorrhea (

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