Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Nails
Nails – brittle
(2001): Önder M+, JDermatolTreat12, 115
Nails – elkonyxis
(2005): Yung A+, Br J Dermatol 153(3), 671
Nails – growth
(1994): Litt JZ, Beachwood, OH (personal case) (observation)
Nails – herpetic whitlow
(2003): Stetson CL+, Int J Dermatol 42(6), 496
Nails – median canaliform dystrophy
(1997): Dharmagunawardena B+, Br J Dermatol
(1992): Bottomley WW+, Br J Dermatol 127, 447
(1988): Bigby M+, JAmAcadDermatol18, 543
Nails – onycholysis
(2005): Al-Mutairi N+, J Drugs Dermatol 4(3), 369
(2001): Önder M+, JDermatolTreat12, 115
(1988): Bigby M+, JAmAcadDermatol18, 543
Nails – paronychia
(1998): Lepine EM, Rock Hill, SC (from Internet) (observation)
(1988): Bigby M+, JAmAcadDermatol18, 543
(1986): DeRaeve L+, Dermatologica 172, 278
(1984): Blumental G, JAmAcadDermatol10, 677
Nails – periungual hemorrhage
(1997): Leal G, Fortaleza, Brazil (from Internet) (observation)
Eyes
Blepharoconjunctivitis
(2001): Fraunfelder FT+, Am J Ophthalmol 132(3), 299
Corneal opacity
(2004): Fraunfelder FW, Drugs Today (Barc) 40(1), 23
Keratitis
(2004): Fraunfelder FW, Drugs Today (Barc) 40(1), 23
Myopia
(2004): Fraunfelder FW, Drugs Today 40(1), 23
Ocular transient discomfort
(2004): Fraunfelder FW, Drugs Today (Barc) 40(1), 23
Optic edema
(2005): Wenham CJ+, Br J Hosp Med (London) 66(11), 644
Photophobia
(2004): Fraunfelder FW, Drugs Today (Barc) 40(1), 23
Vision impaired
(2004): Fraunfelder FW, Drugs Today (Barc) 40(1), 23
Other
Abdominal pain
(2005): Al-Mutairi N+, J Drugs Dermatol 4(3), 369
Death
Gynecomastia
(1994): Shelley WB+, Cutis 54, 149 (passim)
(1992): Fluckiger R, Schweiz Rundsch Med Prax (German)
81, 1370
Hoarseness
(2006): Kim HS+, J Eur Acad Dermatol Venereol 20(10), 1389
Myalgia/Myositis/Myopathy/Myotoxicity
(1998): Heudes AM+, Ann Dermatol Venereol 125(2), 94
(1996): Fiallo P+, Arch Dermatol 132, 1521
(1986): Hodak E, BMJ 293, 425
Pseudoporphyria
(1993): Riordan CA+, Clin Exp Dermatol 18, 69
Rhabdomyolysis
(2001): Trauner MA+, Dermatology Online Journal 5, 2
(2001): Zabawski E, Longwood, TX (from Internet)
(observation)
(1998): Heudes AM+, Ann Dermatol Venereol 125(2), 94
ISOXSUPRINE
Trade names: Duvadilan; Isoxine; Sincen; Vasodilan; Vasolan;
Vasosuprina; Voxsuprine; Xuprin
Indications: Peripheral vascular disease, Raynaud’s phenomenon
Category: Adrenergic beta-receptor agonist
Half-life: N/A
Skin
Dermatitis
ISRADIPINE
Reactions
Trade names: DynaCirc (Reliant); Dynacirc SRO; Lomir; Lomir
SRO; Prescal; Vascal
Indications: Hypertension
Category: Calcium channel blocker
Half-life: 8 hours
Clinically important, potentially hazardous interactions
with: epirubicin, imatinib
Reactions
ISRADIPINE 309
Skin
Diaphoresis (