Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
ISOCARBOXAZID Trade names: Enerzer; Marplan (Oxford) Indications: Depression Category: Antidepressant; Monoamine oxidase (MAO) inhibitor Half-life: N/A Clinically important, potentially hazardous interactions with: amitriptyline, amoxapine, bupropion, citalopram, clomipramine, desipramine, doxepin, fluoxetine, fluvoxamine, imipramine, meperidine, nefazodone, nortriptyline, paroxetine, protriptyline, rizatriptan, sertraline, sibutramine, sumatriptan, trimipramine, tryptophan, venlafaxine, zolmitriptan Reactions Skin Diaphoresis Exanthems (7%) Peripheral edema (1–10%) Photosensitivity (4%) Pruritus (4%) Rash (sic) Telangiectasia Mucosal Tongue black Xerostomia (1–10%) (1984): Zisook S, J Clin Psychiatry 45(7 Pt 2), 53 ISOETHARINE Trade names: Arm-a-Med; Asthmalitan; Beta-2; Bronkomed; Dey-Lute; Numotac Indications: Bronchial asthma Category: Adrenergic beta-receptor agonist Half-life: N/A Clinically important, potentially hazardous interactions with: phenelzine Reactions Mucosal Xerostomia (1–10%) Other Anaphylactoid reactions/Anaphylaxis (1982): Twarog FJ+, JAMA 248, 2030 ISOFLURANE Trade names: Aerrane; Floran; Forane (Baxter); Forene; Forthane; Isofluran; Isoflurano; Isofor; Isorane; Lisorane; Sofloran; Tensocold Indications: Maintenance of general anesthesia Category: Anesthetic, inhalation Half-life: N/A Onset of action: 7–10 minutes Clinically important, potentially hazardous interactions with: cisatracurium, doxacurium, muscle relaxants, pancuronium, rapacuronium Reactions Skin Shivering (post-operative) Other Death (2006): Ihtiyar E+, Indian J Gastroenterol 25(1), 41 ISONIAZID Synonym: INH Trade names: Cemidon; Diazid; Isotamine; Isozid; Nicotibine; Nicozid; PMS-Isoniazid; Rifamate (Sanofi-Aventis); Rifater (Sanofi- Aventis); Tibinide Indications: Tuberculosis Category: Antibiotic; Antimycobacterial Half-life: 1–4 hours Clinically important, potentially hazardous interactions with: insulin detemir, rifampin Reactions ISONIAZID 305 Skin Acne (1988): Oliwiecki S+, Clin Exp Dermatol 13, 283 (1988): Yamanaka M+, Kekkaku (Japanese) 63, 11 (1982): Rosin MA+, Southern Med J 75, 81 (passim) Acute generalized exanthematous pustulosis (AGEP) (1995): Moreau A+, Int J Dermatol 34, 263 (passim) Angioedema (
306 ISONIAZID (2001): Sharma PK+, JDermatol28(12), 737 Lupus erythematosus (2002): Siddiqui MA+, Am J Ther 9(2), 163 (1994): Yung RL+, Rheum Dis Clin North Am 20, 61 (1992): Hofstra AH+, Drug Metab Dispos 20, 205 (1992): Rubin RL+, J Clin Invest 90, 165 (1992): Salazar-Paramo M+, Ann Rheum Dis 51, 1085 (1992): Skaer TL, Clin Ther 14, 496 (1991): Gatenby PA, Autoimmunity 11, 61 (1990): Guleria R+, Indian J Chest Dis Allied Sci 32, 55 (1989): Ueda Y+, Kekkaku (Japanese) 64, 613 (1988): Jiang M, Chung Kuo I Hsueh Ko Hsueh Yuan Hseuh Pao (Chinese) 10, 379 (1988): Umeki S, Kekkaku (Japanese) 63, 713 (1986): Layer P+, Dtsch Med Wochenschr (German) 111, 1603 (1985): Cush JJ+, Am J Med Sci 290, 36 (1985): Holdiness MR, Int J Dermatol 24, 280 (1985): Kale SA, Postgrad Med 77, 231 (1985): Lovisetto P+, Recenti Prog Med (Italy) 76, 110 (1985): Stratton MA, Clin Pharm 4, 657 (1984): No Author, Lancet 2, 441 (1984): Sim E+, Lancet 2, 422 (1983): Escolar-Castellon F+, Rev Clin Esp (Spanish) 169, 209 (1982): Grunwald M+, Dermatologica 165, 172 (1982): Harmon CE+, Clin Rheum Dis 8, 121 (1981): Reidenberg MM, Arthritis Rheum 24, 1004 (1980): Agarwal MB+, JPostgradMed26, 263 (1980): Condemi JJ, Geriatrics 35(3), 81 (1980): Weinstein A, Prog Clin Immunol 4, 1 Peripheral edema (1999): Muratake T+, Am J Psychiatry 156, 660 (1987): Schmutz JL+, Ann Derm Venereol (French) 114, 569 (1983): Jorgensen J, Int J Dermatol 22, 44 (1981): Meyrick Thomas RH+, BMJ 283, 287 Photosensitivity (1998): Lee AY+, Photodermatol Photoimmunol Photomed 14, 77 (lichenoid) (2 patients) (1987): Schmutz JL+, Ann Dermatol Venereol (French) 114, 569 Pruritus Purpura (1992): Breathnach SM+, Adverse Drug Reactions and the Skin Blackwell, Oxford, 159 (passim) (1982): Rosin MA+, Southern Med J 75, 81 (passim) (1980): Miescher PA+, Clin Haematol 9, 505 Pustules (1993): Webster GF, Clin Dermatol 11, 541 (1985): Yamasaki R+, Br J Dermatol 112, 504 (subcorneal) Rash (sic) (
- Page 330 and 331: GLYBURIDE Synonyms: glibenclamide;
- Page 332 and 333: (1982): Bailin PL+, Clin Rheum Dis
- Page 334 and 335: Acne (1996): Lee PK+, JAmAcadDermat
- Page 336 and 337: (2006): Bonkovsky HL, AnnInternMed1
- Page 338 and 339: Peripheral edema (>10%) Purpura Urt
- Page 340 and 341: (1984): Binder RL+, J Clin Psychiat
- Page 342 and 343: HEPARIN Trade names: Calcilean; Cal
- Page 344 and 345: (1990): Rogerson SJ+, BMJ 301, 345
- Page 346 and 347: (1991): Vitris M+, Dakar Med 36(1),
- Page 348 and 349: Other Anaphylactoid reactions/Anaph
- Page 350 and 351: Exanthems Exfoliative dermatitis Fi
- Page 352 and 353: HYDROMORPHONE Trade names: Dilaudid
- Page 354 and 355: (1994): Perrot JL+, Ann Dermatol Ve
- Page 356 and 357: Edema (
- Page 358 and 359: (1994): Halpern SM, Arch Dermatol 1
- Page 360 and 361: Mucosal Oral lesions Sialorrhea (
- Page 362 and 363: IMIGLUCERASE Trade name: Cerezyme (
- Page 364 and 365: (2001): Fife KH+, Sex Transm Dis 28
- Page 366 and 367: Herpes simplex (
- Page 368 and 369: (2004): Scheinfeld N, J Drugs Derma
- Page 370 and 371: (2000): Poole PJ+, Cochrane Databas
- Page 372 and 373: Injection-site pain (2006): Moyes V
- Page 374 and 375: (2002): Tothova E+, Neoplasma 49(2)
- Page 376 and 377: (1995): Shinohara K, NEnglJMed333,
- Page 378 and 379: IOPROMIDE Trade name: Ultravist (Be
- Page 382 and 383: ISOSORBIDE Trade name: Ismotic Indi
- Page 384 and 385: Nails Nails - brittle (2001): Önde
- Page 386 and 387: Serum sickness (1998): Park H+, Ann
- Page 388 and 389: (2001): Burstal R+, Anaesth Intensi
- Page 390 and 391: Pruritus (1-10%) Psoriasis (1992):
- Page 392 and 393: LAMIVUDINE Synonym: 3TC Trade names
- Page 394 and 395: (2006): Fix OK+, Clin Gastroenterol
- Page 396 and 397: Eyelashes - ptosis (2005): Casson R
- Page 398 and 399: LETROZOLE Trade name: Femara (Novar
- Page 400 and 401: Other Abdominal pain (2003): Cramer
- Page 402 and 403: Photosensitivity (
- Page 404 and 405: (2002): Kalin JR+, JForensicSci47(5
- Page 406 and 407: (2002): Serratrice J+, Am J Ophthal
- Page 408 and 409: (1981): Hess EV, Arthritis Rheum 24
- Page 410 and 411: Purpura (
- Page 412 and 413: Reactions Skin Angioedema (
- Page 414 and 415: Other Abdominal pain (7%) Cough (1%
- Page 416 and 417: Reactions Skin Acne (1998): Wollina
- Page 418 and 419: (1983): Nusbaum BP+, Arch Dermatol
- Page 420 and 421: (1997): O’Reilly FM+, American Ac
- Page 422 and 423: MEMANTINE Trade names: Akatinol; Ax
- Page 424 and 425: MERCAPTOPURINE Synonyms: 6-mercapto
- Page 426 and 427: (1998): Leal G, Fortaleza, Brazil (
- Page 428 and 429: (2002): Caplehorn JR+, Aust N Z J P
306 ISONIAZID<br />
(2001): Sharma PK+, JDermatol28(12), 737<br />
Lupus erythematosus<br />
(2002): Siddiqui MA+, Am J Ther 9(2), 163<br />
(1994): Yung RL+, Rheum Dis Clin North Am 20, 61<br />
(1992): Hofstra AH+, <strong>Drug</strong> Metab Dispos 20, 205<br />
(1992): Rubin RL+, J Clin Invest 90, 165<br />
(1992): Salazar-Paramo M+, Ann Rheum Dis 51, 1085<br />
(1992): Skaer TL, Clin Ther 14, 496<br />
(1991): Gatenby PA, Autoimmunity 11, 61<br />
(1990): Guleria R+, Indian J Chest Dis Allied Sci 32, 55<br />
(1989): Ueda Y+, Kekkaku (Japanese) 64, 613<br />
(1988): Jiang M, Chung Kuo I Hsueh Ko Hsueh Yuan Hseuh Pao<br />
(Chinese) 10, 379<br />
(1988): Umeki S, Kekkaku (Japanese) 63, 713<br />
(1986): Layer P+, Dtsch Med Wochenschr (German) 111, 1603<br />
(1985): Cush JJ+, Am J Med Sci 290, 36<br />
(1985): Holdiness MR, Int J Dermatol 24, 280<br />
(1985): Kale SA, Postgrad Med 77, 231<br />
(1985): Lovisetto P+, Recenti Prog Med (Italy) 76, 110<br />
(1985): Stratton MA, Clin Pharm 4, 657<br />
(1984): No Author, Lancet 2, 441<br />
(1984): Sim E+, Lancet 2, 422<br />
(1983): Escolar-Castellon F+, Rev Clin Esp (Spanish) 169, 209<br />
(1982): Grunwald M+, Dermatologica 165, 172<br />
(1982): Harmon CE+, Clin Rheum Dis 8, 121<br />
(1981): Reidenberg MM, Arthritis Rheum 24, 1004<br />
(1980): Agarwal MB+, JPostgradMed26, 263<br />
(1980): Condemi JJ, Geriatrics 35(3), 81<br />
(1980): Weinstein A, Prog Clin Immunol 4, 1<br />
Peripheral edema<br />
(1999): Muratake T+, Am J Psychiatry 156, 660<br />
(1987): Schmutz JL+, Ann Derm Venereol (French) 114, 569<br />
(1983): Jorgensen J, Int J Dermatol 22, 44<br />
(1981): Meyrick Thomas RH+, BMJ 283, 287<br />
Photosensitivity<br />
(1998): Lee AY+, Photodermatol Photoimmunol Photomed 14, 77<br />
(lichenoid) (2 patients)<br />
(1987): Schmutz JL+, Ann Dermatol Venereol (French) 114, 569<br />
Pruritus<br />
Purpura<br />
(1992): Breathnach SM+, Adverse <strong>Drug</strong> Reactions <strong>and</strong> the Skin<br />
Blackwell, Oxford, 159 (passim)<br />
(1982): Rosin MA+, Southern Med J 75, 81 (passim)<br />
(1980): Miescher PA+, Clin Haematol 9, 505<br />
Pustules<br />
(1993): Webster GF, Clin Dermatol 11, 541<br />
(1985): Yamasaki R+, Br J Dermatol 112, 504 (subcorneal)<br />
Rash (sic) (
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