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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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290 IMMUNE GLOBULIN I.V.<br />

(1996): Hashkes PJ+, Clin Exp Rheumatol 14(6), 673<br />

Other<br />

Anaphylactoid reactions/Anaphylaxis<br />

Application-site pain (16%)<br />

Chills<br />

Cough<br />

(1997): Benincasa P+, Ann Allergy Asthma Immunol 79(3), 189<br />

Death<br />

Fever<br />

(1997): Benincasa P+, Ann Allergy Asthma Immunol 79(3), 189<br />

Hypersensitivity<br />

Myalgia/Myositis/Myopathy/Myotoxicity<br />

Nephrotoxicity<br />

(2004): Orbach H+, Semin Arthritis Rheum 34(3), 593 (from<br />

sucrose)<br />

(2000): Dilhuydy MS+, Presse Med 29(17), 942<br />

(2000): Levy JB+, QJM 93(11), 751 (7%)<br />

INAMRINONE<br />

Trade names: Amcoral; Cartonic; Vestistol<br />

Indications: Congestive heart failure<br />

Category: Phosphodiesterase inhibitor<br />

Half-life: 4.6 hours<br />

Other<br />

Hypersensitivity<br />

Injection-site burning (0.2%)<br />

INDAPAMIDE*<br />

Reactions<br />

Trade names: Dapa-tabs; Fludex; Ipamix; Lozide; Lozol (Sanofi-<br />

Aventis); Naplin; Natrilix; Pamid<br />

Indications: Edema<br />

Category: Diuretic, thiazide<br />

Half-life: 14–18 hours<br />

Clinically important, potentially hazardous interactions<br />

with: digoxin, lithium, zinc<br />

Reactions<br />

Skin<br />

Angioedema<br />

(1994): Gales BJ+, Am J Hosp Pharm 51, 118<br />

(1992): Spinler SA+, Cutis 50, 200<br />

(1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313<br />

Bullous dermatitis<br />

Diaphoresis<br />

Erythema multiforme<br />

(1994): Gales BJ+, Am J Hosp Pharm 51, 118<br />

(1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313<br />

Exanthems<br />

(1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313<br />

Fixed eruption<br />

(1998): De Barrio M+, J Investig Allergol Clin Immunol 8, 253<br />

Necrotizing vasculitis<br />

Pemphigus foliaceus<br />

(2002): Schmutz JL+, Ann Dermatol Venereol 129(8-9), 1085<br />

(2001): Bayramgurler D+, JDermatologTreat12(3), 175<br />

Peripheral edema (

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