Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
(2001): Fife KH+, Sex Transm Dis 28(4), 226 (1999): Perry CM+, Drugs 58(2), 375 Flaking (18–67%) (2006): Hadley G+, J Invest Dermatol 126(6), 1251 (9%) (1999): Perry CM+, Drugs 58(2), 375 (67%) Fungal dermatitis (2–11%) Hypomelanosis (2006): Mendonca CO+, Clin Exp Dermatol 31(5), 721 Induration (5%) Irritation (sic) (16%) (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (16.7%) Pemphigus (2004): Ruocco E+, Eur J Obstet Gynecol Reprod Biol 115(2), 242 (2003): Campagne G+, Eur J Obstet Gynecol Reprod Biol 109(2), 224 Pemphigus foliaceus (2005): Mashiah J+, Arch Dermatol 141(7), 908 (2004): Lin R+, Arch Dermatol 140(7), 889 Pigmentation (2005): Brown T+, JAmAcadDermatol52(4), 715 (2000): Geisse JK, Dermatol Surg 26, 579 Pruritus (22–75%) (2006): Prescrire Int 15(84), 130 (2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477 (2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (75%) (2001): Gollnick H+, IntJSTDAIDS12(1), 22 (1999): Perry CM+, Drugs 58(2), 375 (67%) (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (54.2%) Psoriasis (2006): Fanti PA+, Int J Dermatol 45(12), 1464 (2006): Rajan N+, Clin Exp Dermatol 31(1), 140 Scabbing (4%) Tenderness (local) (12%) (2002): Schroeder TL+, JAmAcadDermatol46(4), 545 (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (12.5%) Ulcerations (5–10%) (2005): Nikkels AF+, Acta Clin Belg 60(5), 227 (2002): Chen TM+, Dermatol Surg 28, 344 (for BCCs) (focal) (2002): Emmet S, Solana Beach, CA (topical on lips) (from Internet) (observation) (2001): Fife KH+, Sex Transm Dis 28(4), 226 (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (10.4%) Vesiculation (2–3%) (2001): Fife KH+, Sex Transm Dis 28(4), 226 Mucosal Aphthous stomatitis (2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35 (2004): Emmet S, San Diego, CA (from Internet) (observation) (2004): Emmet S, Solana Beach, CA (3 cases) (from Internet) (observation) (2004): Panagotacos P, San Francisco, CA (from Internet) (observation) (2002): Goldblum O, Pittsburgh, PA (topical on face and lips) (from Internet) (observation) (2002): Kaufmann MD, New York, NY (topical on face) (from Internet) (observation) Stomatitis (2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35 Tongue edema (2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477 Hair Hair – pigmentation (of white hair) (2002): Kirschenbaum MB, Chicago, IL (from Internet) (observation) Eyes Ocular pigmentation IMMUNE GLOBULIN I.V. 289 (2004): Emmet S, Solana Beach, CA (from Internet) (observation) Other Application-site reactions (sic) (2001): Barba AR+, Dermatol Online J 7(1), 20 (2001): Gollnick H+, IntJSTDAIDS12, 22 (2000): Kagy MK+, Dermatol Surg 26(6), 577 (for BCCs) Cough (2004): Emmet S, Solana Beach, CA (from Internet) (observation) Injection-site Varicella-like eruption (2006): Holcomb K+, JDrugsDermatol5(9), 863 Myalgia/Myositis/Myopathy/Myotoxicity (1%) (2002): Sorkin MJ, Denver, CO (topical) (from Internet) (observation) Pain (2–11%) (2006): Prescrire Int 15(84), 130 (2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (11%) (2001): Gollnick H+, IntJSTDAIDS12(1), 22 (1998): Beutner KR+, JAmAcadDermatol38(2), 230 IMMUNE GLOBULIN I.V. Synonyms: IGIV; IVIG Trade names: Allerglobuline; Baygam; Beriglobulin; Citax; Endobulin; Gamafine; Gamastan; Gamimune (Bayer); Gamma 16; Gammabulin; Gammagard (Baxter); Gammar P.I.V (ZLB Behring); Gammer-IV; Gammonayiv; Gamunex (Bayer); IG Gamma; IGIM; Interglobin; IV Globulin-S; Iveegam (Baxter); Octagam; Panglobulin (American Red Cross); Pentaglobin; Polygam S/D (American Red Cross); Sandoglobulin; Sandoglobulina; Sandoglobuline; Venoglobulin (Alpha Therapeutics) Category: Immunomodulator Half-life: N/A Clinically important, potentially hazardous interactions with: live vaccines Reactions Skin Baboon syndrome (1999): Barbaud A+, Dermatology 199(3), 258 Cyanosis Diaphoresis Dyshidrosis (2003): Uyttendaele H+, J Drugs Dermatol 2(3), 337 Eczema (2003): Eastern J, N Caldwell, NJ (generalized) (from Internet) (observation) Lichenoid eruption (1998): Smith KJ+, J Cutan Med Surg 3(2), 96 Lymphocytic vasculitis (2006): Bodemer AA+, JAmAcadDermatolA(5), S112 Pallor Pompholyx (1999): Iannaccone S+, Neurology 53(5), 1154 Rash (sic) (2003): Wittstock M+, Eur Neurol 50(3), 172 Toxic epidermal necrolysis (2006): Trent J+, Seminars Cutan Med Surg 25(2), 91 Urticaria Vasculitis (2001): Odum J+, NephrolDialTransplant16(2), 403 (1998): Howse M+, BMJ 317(7168), 1291
290 IMMUNE GLOBULIN I.V. (1996): Hashkes PJ+, Clin Exp Rheumatol 14(6), 673 Other Anaphylactoid reactions/Anaphylaxis Application-site pain (16%) Chills Cough (1997): Benincasa P+, Ann Allergy Asthma Immunol 79(3), 189 Death Fever (1997): Benincasa P+, Ann Allergy Asthma Immunol 79(3), 189 Hypersensitivity Myalgia/Myositis/Myopathy/Myotoxicity Nephrotoxicity (2004): Orbach H+, Semin Arthritis Rheum 34(3), 593 (from sucrose) (2000): Dilhuydy MS+, Presse Med 29(17), 942 (2000): Levy JB+, QJM 93(11), 751 (7%) INAMRINONE Trade names: Amcoral; Cartonic; Vestistol Indications: Congestive heart failure Category: Phosphodiesterase inhibitor Half-life: 4.6 hours Other Hypersensitivity Injection-site burning (0.2%) INDAPAMIDE* Reactions Trade names: Dapa-tabs; Fludex; Ipamix; Lozide; Lozol (Sanofi- Aventis); Naplin; Natrilix; Pamid Indications: Edema Category: Diuretic, thiazide Half-life: 14–18 hours Clinically important, potentially hazardous interactions with: digoxin, lithium, zinc Reactions Skin Angioedema (1994): Gales BJ+, Am J Hosp Pharm 51, 118 (1992): Spinler SA+, Cutis 50, 200 (1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313 Bullous dermatitis Diaphoresis Erythema multiforme (1994): Gales BJ+, Am J Hosp Pharm 51, 118 (1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313 Exanthems (1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313 Fixed eruption (1998): De Barrio M+, J Investig Allergol Clin Immunol 8, 253 Necrotizing vasculitis Pemphigus foliaceus (2002): Schmutz JL+, Ann Dermatol Venereol 129(8-9), 1085 (2001): Bayramgurler D+, JDermatologTreat12(3), 175 Peripheral edema (
- Page 314 and 315: Reactions Skin Angioedema Erythema
- Page 316 and 317: Reactions Skin Acne (
- Page 318 and 319: Thrombophlebitis *Note: Furosemide
- Page 320 and 321: GANCICLOVIR Trade names: Cymevan; C
- Page 322 and 323: (2002): Baselga J+, J Clin Oncol 20
- Page 324 and 325: (2003): D’Alessandro V+, Clin Ter
- Page 326 and 327: (1996): Merlob P+, Cutis 57, 429 (n
- Page 328 and 329: Hair Hair - alopecia (>2%) Nails Na
- Page 330 and 331: GLYBURIDE Synonyms: glibenclamide;
- Page 332 and 333: (1982): Bailin PL+, Clin Rheum Dis
- Page 334 and 335: Acne (1996): Lee PK+, JAmAcadDermat
- Page 336 and 337: (2006): Bonkovsky HL, AnnInternMed1
- Page 338 and 339: Peripheral edema (>10%) Purpura Urt
- Page 340 and 341: (1984): Binder RL+, J Clin Psychiat
- Page 342 and 343: HEPARIN Trade names: Calcilean; Cal
- Page 344 and 345: (1990): Rogerson SJ+, BMJ 301, 345
- Page 346 and 347: (1991): Vitris M+, Dakar Med 36(1),
- Page 348 and 349: Other Anaphylactoid reactions/Anaph
- Page 350 and 351: Exanthems Exfoliative dermatitis Fi
- Page 352 and 353: HYDROMORPHONE Trade names: Dilaudid
- Page 354 and 355: (1994): Perrot JL+, Ann Dermatol Ve
- Page 356 and 357: Edema (
- Page 358 and 359: (1994): Halpern SM, Arch Dermatol 1
- Page 360 and 361: Mucosal Oral lesions Sialorrhea (
- Page 362 and 363: IMIGLUCERASE Trade name: Cerezyme (
- Page 366 and 367: Herpes simplex (
- Page 368 and 369: (2004): Scheinfeld N, J Drugs Derma
- Page 370 and 371: (2000): Poole PJ+, Cochrane Databas
- Page 372 and 373: Injection-site pain (2006): Moyes V
- Page 374 and 375: (2002): Tothova E+, Neoplasma 49(2)
- Page 376 and 377: (1995): Shinohara K, NEnglJMed333,
- Page 378 and 379: IOPROMIDE Trade name: Ultravist (Be
- Page 380 and 381: ISOCARBOXAZID Trade names: Enerzer;
- Page 382 and 383: ISOSORBIDE Trade name: Ismotic Indi
- Page 384 and 385: Nails Nails - brittle (2001): Önde
- Page 386 and 387: Serum sickness (1998): Park H+, Ann
- Page 388 and 389: (2001): Burstal R+, Anaesth Intensi
- Page 390 and 391: Pruritus (1-10%) Psoriasis (1992):
- Page 392 and 393: LAMIVUDINE Synonym: 3TC Trade names
- Page 394 and 395: (2006): Fix OK+, Clin Gastroenterol
- Page 396 and 397: Eyelashes - ptosis (2005): Casson R
- Page 398 and 399: LETROZOLE Trade name: Femara (Novar
- Page 400 and 401: Other Abdominal pain (2003): Cramer
- Page 402 and 403: Photosensitivity (
- Page 404 and 405: (2002): Kalin JR+, JForensicSci47(5
- Page 406 and 407: (2002): Serratrice J+, Am J Ophthal
- Page 408 and 409: (1981): Hess EV, Arthritis Rheum 24
- Page 410 and 411: Purpura (
- Page 412 and 413: Reactions Skin Angioedema (
(2001): Fife KH+, Sex Transm Dis 28(4), 226<br />
(1999): Perry CM+, <strong>Drug</strong>s 58(2), 375<br />
Flaking (18–67%)<br />
(2006): Hadley G+, J Invest Dermatol 126(6), 1251 (9%)<br />
(1999): Perry CM+, <strong>Drug</strong>s 58(2), 375 (67%)<br />
Fungal dermatitis (2–11%)<br />
Hypomelanosis<br />
(2006): Mendonca CO+, Clin Exp Dermatol 31(5), 721<br />
Induration (5%)<br />
Irritation (sic) (16%)<br />
(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (16.7%)<br />
Pemphigus<br />
(2004): Ruocco E+, Eur J Obstet Gynecol Reprod Biol 115(2), 242<br />
(2003): Campagne G+, Eur J Obstet Gynecol Reprod Biol<br />
109(2), 224<br />
Pemphigus foliaceus<br />
(2005): Mashiah J+, Arch Dermatol 141(7), 908<br />
(2004): Lin R+, Arch Dermatol 140(7), 889<br />
Pigmentation<br />
(2005): Brown T+, JAmAcadDermatol52(4), 715<br />
(2000): Geisse JK, Dermatol Surg 26, 579<br />
Pruritus (22–75%)<br />
(2006): Prescrire Int 15(84), 130<br />
(2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477<br />
(2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (75%)<br />
(2001): Gollnick H+, IntJSTDAIDS12(1), 22<br />
(1999): Perry CM+, <strong>Drug</strong>s 58(2), 375 (67%)<br />
(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (54.2%)<br />
Psoriasis<br />
(2006): Fanti PA+, Int J Dermatol 45(12), 1464<br />
(2006): Rajan N+, Clin Exp Dermatol 31(1), 140<br />
Scabbing (4%)<br />
Tenderness (local) (12%)<br />
(2002): Schroeder TL+, JAmAcadDermatol46(4), 545<br />
(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (12.5%)<br />
Ulcerations (5–10%)<br />
(2005): Nikkels AF+, Acta Clin Belg 60(5), 227<br />
(2002): Chen TM+, Dermatol Surg 28, 344 (for BCCs) (focal)<br />
(2002): Emmet S, Solana Beach, CA (topical on lips) (from<br />
Internet) (observation)<br />
(2001): Fife KH+, Sex Transm Dis 28(4), 226<br />
(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (10.4%)<br />
Vesiculation (2–3%)<br />
(2001): Fife KH+, Sex Transm Dis 28(4), 226<br />
Mucosal<br />
Aphthous stomatitis<br />
(2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35<br />
(2004): Emmet S, San Diego, CA (from Internet) (observation)<br />
(2004): Emmet S, Solana Beach, CA (3 cases) (from Internet)<br />
(observation)<br />
(2004): Panagotacos P, San Francisco, CA (from Internet)<br />
(observation)<br />
(2002): Goldblum O, Pittsburgh, PA (topical on face <strong>and</strong> lips)<br />
(from Internet) (observation)<br />
(2002): Kaufmann MD, New York, NY (topical on face) (from<br />
Internet) (observation)<br />
Stomatitis<br />
(2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35<br />
Tongue edema<br />
(2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477<br />
Hair<br />
Hair – pigmentation (of white hair)<br />
(2002): Kirschenbaum MB, Chicago, IL (from Internet)<br />
(observation)<br />
Eyes<br />
Ocular pigmentation<br />
IMMUNE GLOBULIN I.V. 289<br />
(2004): Emmet S, Solana Beach, CA (from Internet)<br />
(observation)<br />
Other<br />
Application-site reactions (sic)<br />
(2001): Barba AR+, Dermatol Online J 7(1), 20<br />
(2001): Gollnick H+, IntJSTDAIDS12, 22<br />
(2000): Kagy MK+, Dermatol Surg 26(6), 577 (for BCCs)<br />
Cough<br />
(2004): Emmet S, Solana Beach, CA (from Internet)<br />
(observation)<br />
Injection-site Varicella-like eruption<br />
(2006): Holcomb K+, J<strong>Drug</strong>sDermatol5(9), 863<br />
Myalgia/Myositis/Myopathy/Myotoxicity (1%)<br />
(2002): Sorkin MJ, Denver, CO (topical) (from Internet)<br />
(observation)<br />
Pain (2–11%)<br />
(2006): Prescrire Int 15(84), 130<br />
(2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (11%)<br />
(2001): Gollnick H+, IntJSTDAIDS12(1), 22<br />
(1998): Beutner KR+, JAmAcadDermatol38(2), 230<br />
IMMUNE GLOBULIN I.V.<br />
Synonyms: IGIV; IVIG<br />
Trade names: Allerglobuline; Baygam; Beriglobulin; Citax;<br />
Endobulin; Gamafine; Gamastan; Gamimune (Bayer); Gamma 16;<br />
Gammabulin; Gammagard (Baxter); Gammar P.I.V (ZLB Behring);<br />
Gammer-IV; Gammonayiv; Gamunex (Bayer); IG Gamma; IGIM;<br />
Interglobin; IV Globulin-S; Iveegam (Baxter); Octagam;<br />
Panglobulin (American Red Cross); Pentaglobin; Polygam S/D<br />
(American Red Cross); S<strong>and</strong>oglobulin; S<strong>and</strong>oglobulina;<br />
S<strong>and</strong>oglobuline; Venoglobulin (Alpha Therapeutics)<br />
Category: Immunomodulator<br />
Half-life: N/A<br />
Clinically important, potentially hazardous interactions<br />
with: live vaccines<br />
Reactions<br />
Skin<br />
Baboon syndrome<br />
(1999): Barbaud A+, Dermatology 199(3), 258<br />
Cyanosis<br />
Diaphoresis<br />
Dyshidrosis<br />
(2003): Uyttendaele H+, J <strong>Drug</strong>s Dermatol 2(3), 337<br />
Eczema<br />
(2003): Eastern J, N Caldwell, NJ (generalized) (from Internet)<br />
(observation)<br />
Lichenoid eruption<br />
(1998): Smith KJ+, J Cutan Med Surg 3(2), 96<br />
Lymphocytic vasculitis<br />
(2006): Bodemer AA+, JAmAcadDermatolA(5), S112<br />
Pallor<br />
Pompholyx<br />
(1999): Iannaccone S+, Neurology 53(5), 1154<br />
Rash (sic)<br />
(2003): Wittstock M+, Eur Neurol 50(3), 172<br />
Toxic epidermal necrolysis<br />
(2006): Trent J+, Seminars Cutan Med Surg 25(2), 91<br />
Urticaria<br />
Vasculitis<br />
(2001): Odum J+, NephrolDialTransplant16(2), 403<br />
(1998): Howse M+, BMJ 317(7168), 1291