Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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(2001): Fife KH+, Sex Transm Dis 28(4), 226 (1999): Perry CM+, Drugs 58(2), 375 Flaking (18–67%) (2006): Hadley G+, J Invest Dermatol 126(6), 1251 (9%) (1999): Perry CM+, Drugs 58(2), 375 (67%) Fungal dermatitis (2–11%) Hypomelanosis (2006): Mendonca CO+, Clin Exp Dermatol 31(5), 721 Induration (5%) Irritation (sic) (16%) (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (16.7%) Pemphigus (2004): Ruocco E+, Eur J Obstet Gynecol Reprod Biol 115(2), 242 (2003): Campagne G+, Eur J Obstet Gynecol Reprod Biol 109(2), 224 Pemphigus foliaceus (2005): Mashiah J+, Arch Dermatol 141(7), 908 (2004): Lin R+, Arch Dermatol 140(7), 889 Pigmentation (2005): Brown T+, JAmAcadDermatol52(4), 715 (2000): Geisse JK, Dermatol Surg 26, 579 Pruritus (22–75%) (2006): Prescrire Int 15(84), 130 (2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477 (2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (75%) (2001): Gollnick H+, IntJSTDAIDS12(1), 22 (1999): Perry CM+, Drugs 58(2), 375 (67%) (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (54.2%) Psoriasis (2006): Fanti PA+, Int J Dermatol 45(12), 1464 (2006): Rajan N+, Clin Exp Dermatol 31(1), 140 Scabbing (4%) Tenderness (local) (12%) (2002): Schroeder TL+, JAmAcadDermatol46(4), 545 (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (12.5%) Ulcerations (5–10%) (2005): Nikkels AF+, Acta Clin Belg 60(5), 227 (2002): Chen TM+, Dermatol Surg 28, 344 (for BCCs) (focal) (2002): Emmet S, Solana Beach, CA (topical on lips) (from Internet) (observation) (2001): Fife KH+, Sex Transm Dis 28(4), 226 (1998): Beutner KR+, JAmAcadDermatol38(2), 230 (10.4%) Vesiculation (2–3%) (2001): Fife KH+, Sex Transm Dis 28(4), 226 Mucosal Aphthous stomatitis (2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35 (2004): Emmet S, San Diego, CA (from Internet) (observation) (2004): Emmet S, Solana Beach, CA (3 cases) (from Internet) (observation) (2004): Panagotacos P, San Francisco, CA (from Internet) (observation) (2002): Goldblum O, Pittsburgh, PA (topical on face and lips) (from Internet) (observation) (2002): Kaufmann MD, New York, NY (topical on face) (from Internet) (observation) Stomatitis (2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35 Tongue edema (2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477 Hair Hair – pigmentation (of white hair) (2002): Kirschenbaum MB, Chicago, IL (from Internet) (observation) Eyes Ocular pigmentation IMMUNE GLOBULIN I.V. 289 (2004): Emmet S, Solana Beach, CA (from Internet) (observation) Other Application-site reactions (sic) (2001): Barba AR+, Dermatol Online J 7(1), 20 (2001): Gollnick H+, IntJSTDAIDS12, 22 (2000): Kagy MK+, Dermatol Surg 26(6), 577 (for BCCs) Cough (2004): Emmet S, Solana Beach, CA (from Internet) (observation) Injection-site Varicella-like eruption (2006): Holcomb K+, JDrugsDermatol5(9), 863 Myalgia/Myositis/Myopathy/Myotoxicity (1%) (2002): Sorkin MJ, Denver, CO (topical) (from Internet) (observation) Pain (2–11%) (2006): Prescrire Int 15(84), 130 (2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (11%) (2001): Gollnick H+, IntJSTDAIDS12(1), 22 (1998): Beutner KR+, JAmAcadDermatol38(2), 230 IMMUNE GLOBULIN I.V. Synonyms: IGIV; IVIG Trade names: Allerglobuline; Baygam; Beriglobulin; Citax; Endobulin; Gamafine; Gamastan; Gamimune (Bayer); Gamma 16; Gammabulin; Gammagard (Baxter); Gammar P.I.V (ZLB Behring); Gammer-IV; Gammonayiv; Gamunex (Bayer); IG Gamma; IGIM; Interglobin; IV Globulin-S; Iveegam (Baxter); Octagam; Panglobulin (American Red Cross); Pentaglobin; Polygam S/D (American Red Cross); Sandoglobulin; Sandoglobulina; Sandoglobuline; Venoglobulin (Alpha Therapeutics) Category: Immunomodulator Half-life: N/A Clinically important, potentially hazardous interactions with: live vaccines Reactions Skin Baboon syndrome (1999): Barbaud A+, Dermatology 199(3), 258 Cyanosis Diaphoresis Dyshidrosis (2003): Uyttendaele H+, J Drugs Dermatol 2(3), 337 Eczema (2003): Eastern J, N Caldwell, NJ (generalized) (from Internet) (observation) Lichenoid eruption (1998): Smith KJ+, J Cutan Med Surg 3(2), 96 Lymphocytic vasculitis (2006): Bodemer AA+, JAmAcadDermatolA(5), S112 Pallor Pompholyx (1999): Iannaccone S+, Neurology 53(5), 1154 Rash (sic) (2003): Wittstock M+, Eur Neurol 50(3), 172 Toxic epidermal necrolysis (2006): Trent J+, Seminars Cutan Med Surg 25(2), 91 Urticaria Vasculitis (2001): Odum J+, NephrolDialTransplant16(2), 403 (1998): Howse M+, BMJ 317(7168), 1291

290 IMMUNE GLOBULIN I.V. (1996): Hashkes PJ+, Clin Exp Rheumatol 14(6), 673 Other Anaphylactoid reactions/Anaphylaxis Application-site pain (16%) Chills Cough (1997): Benincasa P+, Ann Allergy Asthma Immunol 79(3), 189 Death Fever (1997): Benincasa P+, Ann Allergy Asthma Immunol 79(3), 189 Hypersensitivity Myalgia/Myositis/Myopathy/Myotoxicity Nephrotoxicity (2004): Orbach H+, Semin Arthritis Rheum 34(3), 593 (from sucrose) (2000): Dilhuydy MS+, Presse Med 29(17), 942 (2000): Levy JB+, QJM 93(11), 751 (7%) INAMRINONE Trade names: Amcoral; Cartonic; Vestistol Indications: Congestive heart failure Category: Phosphodiesterase inhibitor Half-life: 4.6 hours Other Hypersensitivity Injection-site burning (0.2%) INDAPAMIDE* Reactions Trade names: Dapa-tabs; Fludex; Ipamix; Lozide; Lozol (Sanofi- Aventis); Naplin; Natrilix; Pamid Indications: Edema Category: Diuretic, thiazide Half-life: 14–18 hours Clinically important, potentially hazardous interactions with: digoxin, lithium, zinc Reactions Skin Angioedema (1994): Gales BJ+, Am J Hosp Pharm 51, 118 (1992): Spinler SA+, Cutis 50, 200 (1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313 Bullous dermatitis Diaphoresis Erythema multiforme (1994): Gales BJ+, Am J Hosp Pharm 51, 118 (1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313 Exanthems (1987): Stricker BHC+, Br Med J Clin Res Ed 295, 1313 Fixed eruption (1998): De Barrio M+, J Investig Allergol Clin Immunol 8, 253 Necrotizing vasculitis Pemphigus foliaceus (2002): Schmutz JL+, Ann Dermatol Venereol 129(8-9), 1085 (2001): Bayramgurler D+, JDermatologTreat12(3), 175 Peripheral edema (

(2001): Fife KH+, Sex Transm Dis 28(4), 226<br />

(1999): Perry CM+, <strong>Drug</strong>s 58(2), 375<br />

Flaking (18–67%)<br />

(2006): Hadley G+, J Invest Dermatol 126(6), 1251 (9%)<br />

(1999): Perry CM+, <strong>Drug</strong>s 58(2), 375 (67%)<br />

Fungal dermatitis (2–11%)<br />

Hypomelanosis<br />

(2006): Mendonca CO+, Clin Exp Dermatol 31(5), 721<br />

Induration (5%)<br />

Irritation (sic) (16%)<br />

(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (16.7%)<br />

Pemphigus<br />

(2004): Ruocco E+, Eur J Obstet Gynecol Reprod Biol 115(2), 242<br />

(2003): Campagne G+, Eur J Obstet Gynecol Reprod Biol<br />

109(2), 224<br />

Pemphigus foliaceus<br />

(2005): Mashiah J+, Arch Dermatol 141(7), 908<br />

(2004): Lin R+, Arch Dermatol 140(7), 889<br />

Pigmentation<br />

(2005): Brown T+, JAmAcadDermatol52(4), 715<br />

(2000): Geisse JK, Dermatol Surg 26, 579<br />

Pruritus (22–75%)<br />

(2006): Prescrire Int 15(84), 130<br />

(2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477<br />

(2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (75%)<br />

(2001): Gollnick H+, IntJSTDAIDS12(1), 22<br />

(1999): Perry CM+, <strong>Drug</strong>s 58(2), 375 (67%)<br />

(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (54.2%)<br />

Psoriasis<br />

(2006): Fanti PA+, Int J Dermatol 45(12), 1464<br />

(2006): Rajan N+, Clin Exp Dermatol 31(1), 140<br />

Scabbing (4%)<br />

Tenderness (local) (12%)<br />

(2002): Schroeder TL+, JAmAcadDermatol46(4), 545<br />

(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (12.5%)<br />

Ulcerations (5–10%)<br />

(2005): Nikkels AF+, Acta Clin Belg 60(5), 227<br />

(2002): Chen TM+, Dermatol Surg 28, 344 (for BCCs) (focal)<br />

(2002): Emmet S, Solana Beach, CA (topical on lips) (from<br />

Internet) (observation)<br />

(2001): Fife KH+, Sex Transm Dis 28(4), 226<br />

(1998): Beutner KR+, JAmAcadDermatol38(2), 230 (10.4%)<br />

Vesiculation (2–3%)<br />

(2001): Fife KH+, Sex Transm Dis 28(4), 226<br />

Mucosal<br />

Aphthous stomatitis<br />

(2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35<br />

(2004): Emmet S, San Diego, CA (from Internet) (observation)<br />

(2004): Emmet S, Solana Beach, CA (3 cases) (from Internet)<br />

(observation)<br />

(2004): Panagotacos P, San Francisco, CA (from Internet)<br />

(observation)<br />

(2002): Goldblum O, Pittsburgh, PA (topical on face <strong>and</strong> lips)<br />

(from Internet) (observation)<br />

(2002): Kaufmann MD, New York, NY (topical on face) (from<br />

Internet) (observation)<br />

Stomatitis<br />

(2005): Chakrabarty AK+, JAmAcadDermatol52(2 Suppl 1), 35<br />

Tongue edema<br />

(2004): Barton JC, J Am Acad Dermatol 2004 Sep 51(3), 477<br />

Hair<br />

Hair – pigmentation (of white hair)<br />

(2002): Kirschenbaum MB, Chicago, IL (from Internet)<br />

(observation)<br />

Eyes<br />

Ocular pigmentation<br />

IMMUNE GLOBULIN I.V. 289<br />

(2004): Emmet S, Solana Beach, CA (from Internet)<br />

(observation)<br />

Other<br />

Application-site reactions (sic)<br />

(2001): Barba AR+, Dermatol Online J 7(1), 20<br />

(2001): Gollnick H+, IntJSTDAIDS12, 22<br />

(2000): Kagy MK+, Dermatol Surg 26(6), 577 (for BCCs)<br />

Cough<br />

(2004): Emmet S, Solana Beach, CA (from Internet)<br />

(observation)<br />

Injection-site Varicella-like eruption<br />

(2006): Holcomb K+, J<strong>Drug</strong>sDermatol5(9), 863<br />

Myalgia/Myositis/Myopathy/Myotoxicity (1%)<br />

(2002): Sorkin MJ, Denver, CO (topical) (from Internet)<br />

(observation)<br />

Pain (2–11%)<br />

(2006): Prescrire Int 15(84), 130<br />

(2003): Bayerl C+, Br J Dermatol 149 Suppl 66, 25 (11%)<br />

(2001): Gollnick H+, IntJSTDAIDS12(1), 22<br />

(1998): Beutner KR+, JAmAcadDermatol38(2), 230<br />

IMMUNE GLOBULIN I.V.<br />

Synonyms: IGIV; IVIG<br />

Trade names: Allerglobuline; Baygam; Beriglobulin; Citax;<br />

Endobulin; Gamafine; Gamastan; Gamimune (Bayer); Gamma 16;<br />

Gammabulin; Gammagard (Baxter); Gammar P.I.V (ZLB Behring);<br />

Gammer-IV; Gammonayiv; Gamunex (Bayer); IG Gamma; IGIM;<br />

Interglobin; IV Globulin-S; Iveegam (Baxter); Octagam;<br />

Panglobulin (American Red Cross); Pentaglobin; Polygam S/D<br />

(American Red Cross); S<strong>and</strong>oglobulin; S<strong>and</strong>oglobulina;<br />

S<strong>and</strong>oglobuline; Venoglobulin (Alpha Therapeutics)<br />

Category: Immunomodulator<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: live vaccines<br />

Reactions<br />

Skin<br />

Baboon syndrome<br />

(1999): Barbaud A+, Dermatology 199(3), 258<br />

Cyanosis<br />

Diaphoresis<br />

Dyshidrosis<br />

(2003): Uyttendaele H+, J <strong>Drug</strong>s Dermatol 2(3), 337<br />

Eczema<br />

(2003): Eastern J, N Caldwell, NJ (generalized) (from Internet)<br />

(observation)<br />

Lichenoid eruption<br />

(1998): Smith KJ+, J Cutan Med Surg 3(2), 96<br />

Lymphocytic vasculitis<br />

(2006): Bodemer AA+, JAmAcadDermatolA(5), S112<br />

Pallor<br />

Pompholyx<br />

(1999): Iannaccone S+, Neurology 53(5), 1154<br />

Rash (sic)<br />

(2003): Wittstock M+, Eur Neurol 50(3), 172<br />

Toxic epidermal necrolysis<br />

(2006): Trent J+, Seminars Cutan Med Surg 25(2), 91<br />

Urticaria<br />

Vasculitis<br />

(2001): Odum J+, NephrolDialTransplant16(2), 403<br />

(1998): Howse M+, BMJ 317(7168), 1291

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