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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Exanthems<br />

Exfoliative dermatitis<br />

Fixed eruption<br />

(1985): Kauppinen K+, Br J Dermatol 112, 575<br />

Lichenoid eruption<br />

(2006): Pfab F+, Allergy 61(6), 786 (with irbesartan)<br />

(1986): Halevy S+, Ann Allergy 56, 402<br />

Lupus erythematosus<br />

(2002): Boye T+, World Congress Dermatol Poster, 0088<br />

(1998): Callen JP, Academy ’98 Meeting (5 patients)<br />

(1996): Litt JZ, Beachwood, OH (personal case) (observation)<br />

(1995): Brown CW+, Clin Toxicol 33, 729<br />

(1995): Rich MW+, J Rheumatol 22, 1001<br />

(1993): Goodrich AL+, JAmAcadDermatol28, 1001<br />

(1991): Wollenberg A+, Hautarzt (German) 42, 709<br />

(1989): Alanko K+, Acta Derm Venereol (Stockh) 69, 223<br />

(1989): Fine RM, Int J Dermatol 28, 375 (Comment)<br />

(1989): Parodi A+, Photodermatology 6, 100<br />

(1988): Darken M+, JAmAcadDermatol18, 38<br />

(1986): Berbis Ph, Ann Dermatol Venereol 113, 1245 (thiazides)<br />

(1985): Reed BR+, AnnInternMed103, 49<br />

Photosensitivity (10%)<br />

Mucosal<br />

Xerostomia<br />

Other<br />

Hot flashes<br />

*Note: Hydrocodone is included in many combination drugs. Other<br />

medications that can be included in these preparations include:<br />

phenylpropanolamine, phenylephrine, pyrilamine, pseudoephedrine,<br />

acetaminophen, ibuprofen, <strong>and</strong> others<br />

HYDROCORTISONE<br />

HYDROCORTISONE 275<br />

Trade names: Ala-Cort (Del-Ray); Cortef (Pharmacia);<br />

Cortenema (Solvay); Hydrocortone (Merck); Hytone (Dermik);<br />

Solu-Cortef (Pharmacia)<br />

Indications: Arthralgias, Ophthalmology, Asthma, Rhinitis (many<br />

more)<br />

Category: Corticosteroid, topical<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: amphotericin B, chlorotrianisene, colestyramine, diuretics,<br />

estrogens, furosemide, insulin, live vaccines, methotrexate, oral<br />

contraceptives, pancuronium, phenobarbital, rifampicin

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