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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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264 HEMOPHILUS B VACCINE<br />

Other<br />

Anaphylactoid reactions/Anaphylaxis<br />

Fever<br />

(1991): MMWR Recomm Rep 40(RR), 1<br />

Hypersensitivity<br />

Injection-site edema<br />

(1991): MMWR Recomm Rep 40(RR), 1<br />

Injection-site induration<br />

Injection-site pain<br />

(1993): de Montalembert M+, Arch Fr Pediatr 50(10), 863<br />

HALCINONIDE<br />

Trade name: Halog (Bristol-Myers Squibb)<br />

Indications: Dermatoses<br />

Category: Corticosteroid, topical<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: live vaccines<br />

Reactions<br />

Skin<br />

Acne<br />

Burning<br />

(1981): Guenther L+, Cutis 28(4), 461<br />

(1980): Akers WA, Arch Dermatol 116(7), 786<br />

Irritation<br />

(1981): Guenther L+, Cutis 28(4), 461<br />

(1980): Akers WA, Arch Dermatol 116(7), 786<br />

Pigmentation<br />

Pruritus<br />

(1981): Guenther L+, Cutis 28(4), 461<br />

(1980): Akers WA, Arch Dermatol 116(7), 786<br />

Rash (sic)<br />

Xerosis<br />

(1980): Akers WA, Arch Dermatol 116(7), 786<br />

Other<br />

Hypersensitivity<br />

(1986): Reitamo S+, JAmAcadDermatol14(4), 582<br />

Infections<br />

HALOBETASOL<br />

Trade name: Ultravate (Westwood Squibb)<br />

Indications: Dermatoses<br />

Category: Corticosteroid, topical<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: live vaccines<br />

Reactions<br />

Skin<br />

Adverse effects (sic)<br />

(1991): Blum G+, JAmAcadDermatol25(6), 1153<br />

(1991): Brunner N+, JAmAcadDermatol25(6), 1160 (rare)<br />

(1991): Datz B+, JAmAcadDermatol25(6), 1157 (5%)<br />

(1991): Goldberg B+, JAmAcadDermatol25(6), 1145 (7%)<br />

(1991): Herz G+, JAmAcadDermatol25(6), 1166 (2%)<br />

Atrophy<br />

(1991): Herz G+, JAmAcadDermatol25(6), 1166 (1 case)<br />

Burning<br />

Erythema<br />

Pruritus<br />

(1991): Yawalkar SJ+, JAmAcadDermatol25(6), 1163<br />

(1990): Watson WA+, Pharmacotherapy 10(2), 107 (2 cases)<br />

Stinging<br />

Xerosis<br />

(1991): Yawalkar SJ+, JAmAcadDermatol25(6), 1163 (1 case)<br />

HALOMETASONE<br />

Trade name: Sicorten<br />

Indications: Dermatoses<br />

Category: Corticosteroid, topical<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: live vaccines<br />

Reactions<br />

Skin<br />

Adverse effects (sic)<br />

(1983): Maeder E+, JIntMedRes11, 48 (mild)<br />

Pruritus<br />

(1983): Weitgasser H+, JIntMedRes11, 34 (4%)<br />

Pustules<br />

(1983): Galbiati G+, JIntMedRes11, 31 (1 case)<br />

HALOPERIDOL<br />

Trade names: Dozic; Duraperidol; Haldol (Ortho-McNeil);<br />

Haloper; Peridol; Seranace; Serenace<br />

Indications: Psychoses, Tourette’s disorder<br />

Category: Antipsychotic, butyrophenone<br />

Half-life: 20 hours<br />

Clinically important, potentially hazardous interactions<br />

with: benztropine, eucalyptus, fluoxetine, lithium,<br />

methotrexate, propranolol<br />

Reactions<br />

Skin<br />

Acne<br />

Cellulitis<br />

(1982): Sacks HS, Hosp Pract Off Ed 17, 179<br />

Dermatitis (

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