Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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242 FURAZOLIDONE Serum sickness *Note: The disulfiram-like reaction consists of facial flushing, diaphoresis, tachycardia, and pounding headache FUROSEMIDE* Trade names: Apo-Furosemide; Discoid; Dryptal; Edenol; Frusid; Furorese; Furoside; Fusid; Henexal; Lasilix; Lasix (Sanofi- Aventis); Novo-Semide; Urex; Uritol Indications: Edema Category: Diuretic, loop Half-life: 0.5–1 hour Clinically important, potentially hazardous interactions with: aliskiren, amikacin, amyl nitrite, digoxin, gentamicin, hydrocortisone, kanamycin, neomycin, probenecid, streptomycin, tobramycin Reactions Skin Acute febrile neutrophilic dermatosis (Sweet’s syndrome) (2005): Govindarajan G+, South Med J 98(5), 570 (1989): Cobb MW, JAmAcadDermatol21, 339 Acute generalized exanthematous pustulosis (AGEP) (2006): Davidovici BB+, Harefuah 145(7), 477 (with vancomycin) (1995): Moreau A+, Int J Dermatol 34, 263 (passim) Bullous dermatitis (

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