Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Toxic epidermal necrolysis Urticaria Vasculitis Xerosis Hair Hair – alopecia (2002): Litt JZ, Beachwood, OH (personal case) (observation) Hair – changes (sic) Nails Nails – changes (sic) Other Anaphylactoid reactions/Anaphylaxis Death Gynecomastia Myalgia/Myositis/Myopathy/Myotoxicity (2002): Lawrence JM+, Expert Opin Pharmacother 3(11), 1631 (1997): 16(1), February (1997): 61(1), February (1995): Garnett WR, Am J Health Syst Pharm 52(15), 1639 Rhabdomyolysis (2005): Andrejak M+, Therapie 60(3), 299 (2005): Atasoyu EM+, Ann Pharmacother 39(7–8), 1368 (with colchicine) (2005): Deak G+, JNephrol18(6), 773 (2002): Lawrence JM+, Expert Opin Pharmacother 3(11), 1631 (2002): Modi JR+, Ann Pharmacother 36(12), 1870 (2002): Sica DA+, Am J Geriatr Cardiol 11(1), 48 (2002): Sica DA+, Curr Opin Nephrol Hypertens 11(2), 123 (1999): Bottorff M, Atherosclerosis 147(Suppl 1), S23 (1995): Farmer JA+, Baillieres Clin Endocrinol Metab 9(4), 825 (1995): Garnett WR, Am J Health Syst Pharm 52(15), 1639 Upper respiratory infection (16%) FLUVOXAMINE Trade names: Apo-Fluvoxamine; Dumirox; Dumyrox; Faverin; Favoxil; Fevarin; Luvox (Solvay); Maveral Indications: Obsessive-compulsive disorder, depression Category: Antidepressant; Selective serotonin reuptake inhibitor Half-life: 15 hours Clinically important, potentially hazardous interactions with: alprazolam, amphetamines, dextroamphetamine, diethylpropion, duloxetine, isocarboxazid, linezolid, MAO inhibitors, mazindol, methadone, methamphetamine, phendimetrazine, phenelzine, phentermine, phenylpropanolamine, pseudoephedrine, ramelteon, ropivacaine, selegiline, sibutramine, St John’s wort, sumatriptan, sympathomimetics, tacrine, theophyllines, tizanidine, tizanidine, tramadol, tranylcypromine, trazodone, troleandomycin, tryptophan, zolmitriptan Reactions Skin Acne (

238 FOLIC ACID Erythema Exanthems (1985): Sparling R+, Clin Lab Haematol 7, 184 Pruritus (

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