Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Toxic epidermal necrolysis
Urticaria
Vasculitis
Xerosis
Hair
Hair – alopecia
(2002): Litt JZ, Beachwood, OH (personal case) (observation)
Hair – changes (sic)
Nails
Nails – changes (sic)
Other
Anaphylactoid reactions/Anaphylaxis
Death
Gynecomastia
Myalgia/Myositis/Myopathy/Myotoxicity
(2002): Lawrence JM+, Expert Opin Pharmacother 3(11), 1631
(1997): 16(1), February
(1997): 61(1), February
(1995): Garnett WR, Am J Health Syst Pharm 52(15), 1639
Rhabdomyolysis
(2005): Andrejak M+, Therapie 60(3), 299
(2005): Atasoyu EM+, Ann Pharmacother 39(7–8), 1368 (with
colchicine)
(2005): Deak G+, JNephrol18(6), 773
(2002): Lawrence JM+, Expert Opin Pharmacother 3(11), 1631
(2002): Modi JR+, Ann Pharmacother 36(12), 1870
(2002): Sica DA+, Am J Geriatr Cardiol 11(1), 48
(2002): Sica DA+, Curr Opin Nephrol Hypertens 11(2), 123
(1999): Bottorff M, Atherosclerosis 147(Suppl 1), S23
(1995): Farmer JA+, Baillieres Clin Endocrinol Metab 9(4), 825
(1995): Garnett WR, Am J Health Syst Pharm 52(15), 1639
Upper respiratory infection (16%)
FLUVOXAMINE
Trade names: Apo-Fluvoxamine; Dumirox; Dumyrox; Faverin;
Favoxil; Fevarin; Luvox (Solvay); Maveral
Indications: Obsessive-compulsive disorder, depression
Category: Antidepressant; Selective serotonin reuptake inhibitor
Half-life: 15 hours
Clinically important, potentially hazardous interactions
with: alprazolam, amphetamines, dextroamphetamine,
diethylpropion, duloxetine, isocarboxazid, linezolid, MAO
inhibitors, mazindol, methadone, methamphetamine,
phendimetrazine, phenelzine, phentermine,
phenylpropanolamine, pseudoephedrine, ramelteon, ropivacaine,
selegiline, sibutramine, St John’s wort, sumatriptan,
sympathomimetics, tacrine, theophyllines, tizanidine, tizanidine,
tramadol, tranylcypromine, trazodone, troleandomycin,
tryptophan, zolmitriptan
Reactions
Skin
Acne (