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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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224 FENTANYL<br />

Exfoliative dermatitis<br />

Fixed eruption<br />

(2001): Vaughan K, Lakewood, WA (from patch) (from Internet)<br />

(observation)<br />

Papulo-nodular lesions (>1%)<br />

Pruritus (3–44%)<br />

(2006): Sarvela PJ+, Acta Anaesthesiol Sc<strong>and</strong> 50(2), 239<br />

(2002): Gurkan Y+, Anesth Analg 95(6), 1763<br />

(2002): Henry A+, RegAnesthPainMed27(5), 538 (intrathecal)<br />

(2002): Nelson KE+, Anesthesiology 96(5), 1070<br />

(1999): Herman NL+, Anesth Analg 89, 378<br />

(1996): Larijani GE+, Pharmacotherapy 16, 958<br />

(1994): Gerwels JW+, JDermatolSurgOncol20, 823<br />

(1992): Badner NH+, Can J Anaesth 39, 330<br />

(1992): Belzarena SD, Anesth Analg 74, 653<br />

(1992): Calis KA+, Clin Pharm 11, 22<br />

(1992): Friesen RH+, Anesthesiology 76, 46 (facial)<br />

(1992): Mosser KH, Am Fam Physician 45, 2289<br />

(1992): Mourisse J+, Acta Anaesthesiol Sc<strong>and</strong> 36, 70<br />

(1992): Paech MJ, Anaesth Intensive Care 20, 15<br />

(1992): S<strong>and</strong>ler ES+, Pediatrics 89, 631<br />

(1992): Varrassi G+, Anaesthesia 47, 558<br />

(1992): White MJ+, Can J Anaesth 39, 594<br />

(1989): Ackerman WE+, Can J Anaesth 36, 388<br />

(1989): Jorrot JC+, AnnFrAnesthRéanim(French) 8, 321 (22%)<br />

(1988): Davies GG+, Anesthesiology 69, 763<br />

(1988): Monk JP+, <strong>Drug</strong>s 36, 286 (40%)<br />

(1986): Shipton EA+, SAfrMedJ70, 325 (13%)<br />

Purpura<br />

(2001): Tweed WA+, Anesth Analg 92, 1442<br />

Pustules (1%)<br />

(1992): S<strong>and</strong>ler ES+, Pediatrics 89, 631<br />

(1992): Stoukides CA+, Clin Pharm 11, 222<br />

Urticaria (10%)<br />

(2001): Litt JZ, Beachwood, OH (personal case) (observation)<br />

(1992): Calis KA+, Clin Pharm 11, 22<br />

Other<br />

Anaphylactoid reactions/Anaphylaxis<br />

(2007): Cummings KC 3rd+, Can J Anaesth 54(4), 301<br />

(2001): Girgis Y, Anaesthesia 56(10), 1016<br />

(2001): Konarzewski W+, Anaesthesia 56(5), 497 (with<br />

propofol) (fatal)<br />

(2001): Lewis S+, Anaesthesia 56(11), 1128<br />

(1990): Ducker P+, ZHautkr(German) 65, 734<br />

Cough<br />

(2007): Yeh CC+, J Clin Anesth 19(1), 53<br />

(2006): Oshima T+, Can J Anaesth 53(8), 753<br />

(2005): Schlimp CJ+, Can J Anaesth 52(2), 207<br />

(2004): P<strong>and</strong>ey CK+, Anesth Analg 99(6), 1696<br />

(2002): Tsou CH+, Acta Anaesthesiol Sin 40(4), 165<br />

(2001): Tweed WA+, Anesth Analg 92(6), 1442<br />

Death<br />

(2005): Ekedahl A+, Lakartidningen 102(39), 2788<br />

(2002): Mertes PM+, Anaesthesia 57(8), 821 (with propofol)<br />

(2002): Reeves MD+, Med J Aust 177(10), 552<br />

(2001): Girgis Y, Anaesthesia 56(10), 1016<br />

Inappropriate secretion of antidiuretic hormone (SIADH)<br />

(2002): Kokko H+, Pharmacotherapy 22(9), 1188<br />

FEVERFEW<br />

Scientific names: Chrysanthemum parthenium; Pyrethrum<br />

parthenium; Tanacetum parthenium<br />

Family: Asteraceae; Compositae<br />

Trade <strong>and</strong> other common names: Atamisa; Featerfoiul;<br />

Featherfew; Featherfoil; MIG-99; Santa Maria<br />

Category: Antipyretic<br />

Purported indications <strong>and</strong> other uses: Fever, headache,<br />

migraine, menstrual irregularities, arthritis, psoriasis, allergy,<br />

asthma, tinnitus, vertigo, nausea, cold, earache, orthopedic<br />

disorders, swollen feet, diarrhea, dyspepsia<br />

Half-life: N/A<br />

Clinically important, potentially hazardous interactions<br />

with: anticoagulants, NSAIDs, warfarin<br />

Reactions<br />

Skin<br />

Adverse effects (sic) (mild)<br />

(2000): Ernst E+, Public Health Nutr 3(4A), 509<br />

Allergic reactions (sic)<br />

(1983): Hausen BM+, Acta Derm Venereol 63(4), 308<br />

Angioedema (lips)<br />

(1998): Awang DVC, Int Med 1, 11<br />

(1985): Johnson ES+, BMJ (Clin Res Ed) 291, 569<br />

Dermatitis<br />

(2006): Verma KK+, Indian J Dermatol Venereol Leprol 72(1), 24<br />

(2002): Paulsen E+, Contact Dermatitis 47(1), 14<br />

(1996): Lamminpaa A+, Contact Dermatitis 34, 330<br />

Prurigo nodularis<br />

(2000): Sharma VK+, Contact Dermatitis 42(4), 235<br />

Mucosal<br />

Oral ulceration<br />

(1998): Awang DVC, Int Med 1, 11<br />

(1985): Johnson ES+, BMJ (Clin Res Ed) 291, 569<br />

FEXOFENADINE<br />

Trade name: Allegra (Sanofi-Aventis)<br />

Indications: Allergic rhinitis, pruritus, urticaria<br />

Category: Histamine H1 receptor antagonist<br />

Half-life: 14.4 hours<br />

Clinically important, potentially hazardous interactions<br />

with: St John’s wort<br />

Reactions<br />

Skin<br />

Acne<br />

(1998): Litt JZ, Beachwood, OH (personal case) (observation)<br />

Psoriasis<br />

(2006): Saraswat A+, Clin Exp Dermatol 31(3), 477 (Pustular)<br />

Pustules<br />

(2006): Saraswat A+, Clin Exp Dermatol 31(3), 477<br />

FILGRASTIM<br />

(See GRANULOCYTE COLONY-STIMULATING FACTOR<br />

(GCSF))

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