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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Other<br />

Anticonvulsant hypersensitivity syndrome<br />

(2004): Papp Z+, Orv Hetil 145(32), 1665<br />

Hypersensitivity<br />

(1999): Conilleau V+, Contact Dermatitis 41(3), 141<br />

Pseudolymphoma<br />

(2005): Masruha MR+, J Neurol Neurosurg Psychiatry<br />

76(11), 1610<br />

ETHOTOIN<br />

Trade names: Accenon; Peganone (Ovation)<br />

Indications: Tonic–clonic (gr<strong>and</strong> mal) seizures<br />

Category: Antiepileptic, hydantoin<br />

Half-life: 3–9 hours<br />

Clinically important, potentially hazardous interactions<br />

with: chloramphenicol, cyclosporine, disulfiram, dopamine,<br />

imatinib, itraconazole<br />

Reactions<br />

Skin<br />

Bullous dermatitis<br />

Fixed eruption<br />

Lupus erythematosus<br />

Purpura<br />

Rash (sic)<br />

Mucosal<br />

Gingival hyperplasia/hypertrophy<br />

Other<br />

Pseudolymphoma<br />

ETIDRONATE<br />

Trade names: Didronate; Didronel (Procter & Gamble);<br />

Difosfen; Dinol; Diphos; Osteum<br />

Indications: Paget’s disease, osteoporosis<br />

Category: Bisphosphonate<br />

Half-life: 6 hours<br />

Reactions<br />

Skin<br />

Angioedema (

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