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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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202 ENFLURANE<br />

Other<br />

Anaphylactoid reactions/Anaphylaxis<br />

(1988): Ganzuka A+, Masui 37(11), 1382<br />

Death<br />

(1998): Asai K+, Eur J Pediatr 157(2), 169<br />

(1995): Schneider M, Anaesth Intensive Care 23(2), 225<br />

(1987): Paull JD+, Anaesthesia 42(11), 1191<br />

Myalgia/Myositis/Myopathy/Myotoxicity<br />

Rhabdomyolysis<br />

(1987): Lee SC+, J Oral Maxillofac Surg 45(9), 789 (with<br />

succinylcholine)<br />

(1987): Lee SC+, Ma Zui Xue Za Zhi 25(2), 97<br />

ENFUVIRTIDE<br />

Trade names: Fuzeon (Roche); T-20<br />

Indications: HIV-1 Infection (in combination with other<br />

antiretroviral agents)<br />

Category: Antiretroviral; HIV cell fusion inhibitor<br />

Half-life: 3.8 hours<br />

Clinically important, potentially hazardous interactions<br />

with: None<br />

Reactions<br />

Skin<br />

Allergic reactions (sic)<br />

(2005): Hayashi T, Nippon Rinsho 63(1), 173<br />

Edema<br />

(2004): Church JA+, Pediatr Infect Dis J 23(8), 713<br />

Exanthems<br />

Herpes simplex (5%)<br />

Papillomas (4.2%)<br />

Pruritus (62%)<br />

Rash (sic)<br />

Eyes<br />

Conjunctivitis (2.4%)<br />

Other<br />

Abdominal pain (3%)<br />

Chills<br />

Cough (7.4%)<br />

Fever<br />

Hypersensitivity (

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