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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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174 DIAZEPAM<br />

Nails<br />

Nails – parrot-beak<br />

Other<br />

Anaphylactoid reactions/Anaphylaxis<br />

(1987): Deardon DJ+, Br J Anaesth 59, 391<br />

Gynecomastia<br />

(2005): Jelenkovic AV+, Ann Pharmacother 39(1), 201<br />

(2000): Hugues FC+, Ann Med Interne (Paris) (French) 151, 10<br />

(passim)<br />

(1994): Llop R+, Ann Pharmacother 28, 671<br />

Hypersensitivity<br />

(2002): Asero R, Allergy 57(12), 1209<br />

Injection-site pain<br />

(2002): Majedi H+, Anesth Analg 95(5), 1297<br />

Injection-site phlebitis (>10%)<br />

(1981): Clarke RSJ, <strong>Drug</strong>s 22, 26 (39%)<br />

(1980): Schou-Olesen A+, Br J Anaesth 52, 609<br />

Porphyria<br />

Porphyria variegata<br />

Rhabdomyolysis<br />

(1982): Bogaerts Y+, Clin Nephrol 17(4), 206<br />

DIAZOXIDE<br />

Trade names: Eudimine; Hyperstat (Schering); Proglicem;<br />

Proglycem; Sefulken<br />

Indications: Hypoglycemia, hypertension<br />

Category: Vasodilator<br />

Half-life: 20–36 hours<br />

Clinically important, potentially hazardous interactions<br />

with: phenytoin<br />

Reactions<br />

Skin<br />

Cellulitis (

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