Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Other Hypersensitivity (2002): Sommer S+, Br J Dermatol 147(2), 266 (1983): Chalmers RJ+, Contact Dermatitis 9(4), 317 (1983): Kuhlwein A+, ZHautkr58(11), 794 Infections (1999): Zimmermann R+, Ann Dermatol Venereol 126(1), 13 (1990): Prawer SE+, Am Fam Physician 41(5), 1531 CLOFARABINE Trade name: Clolar (Genzyme) Indications: Acute lymphoblastic leukemia Category: Antimetabolite Half-life: 5.2 hours Clinically important, potentially hazardous interactions with: hepatotoxic & nephrotoxic drugs Reactions Skin Acral erythema (2003): Chiao N+, Leuk Lymphoma 44(8), 1405 (2 cases) Cellulitis (11%) Dermatitis (sic) (41%) Edema (20%) Erythema (18%) Hand–foot syndrome (2005): Faderl S+, Blood 105(3), 940 (2005): Kline JP+, Expert Opin Pharmacother 6(15), 2711 (2003): Chiao N+, Leuk Lymphoma 44(8), 1405 (13%) Herpes simplex (11%) Petechiae (29%) Pruritus (47%) Rash (sic) (2005): Faderl S+, Blood 105(3), 940 Xerosis (10%) Mucosal Gingival bleeding (15%) Mucosal inflammation (18%) Mucositis (2005): Faderl S+, Blood 105(3), 940 Oral candidiasis (13%) Stomatitis (2005): Kline JP+, Expert Opin Pharmacother 6(15), 2711 Other Abdominal pain (36%) Cough (19%) Injection-site pain (14%) Myalgia/Myositis/Myopathy/Myotoxicity (14%) (2005): Kline JP+, Expert Opin Pharmacother 6(15), 2711 Pain (19%) CLOFAZIMINE Trade names: Clofozine; Hansepran; Lampren; Lamprene (Novartis); Lapren Indications: Leprosy Category: Anti-inflammatory; Antimycobacterial Half-life: 10 days after a single dose Clinically important, potentially hazardous interactions with: fludarabine, pentostatin Reactions CLOFAZIMINE 135 Skin Acne (
136 CLOFAZIMINE Mucosal Cheilitis (candidal) (
- Page 160 and 161: CALFACTANT Trade name: Infasurf (Fo
- Page 162 and 163: CAPSICUM Scientific names: Capsicum
- Page 164 and 165: Lupus erythematosus (2002): Ratliff
- Page 166 and 167: Corneal edema Eyelid twitching Kera
- Page 168 and 169: Stevens-Johnson syndrome (1-10%) (2
- Page 170 and 171: Porphyria variegata (2001): Grieco
- Page 172 and 173: (1983): Rollings HE+, Curr Ther Res
- Page 174 and 175: Dermatitis (1986): Hirata M+, Kokyu
- Page 176 and 177: Other Anaphylactoid reactions/Anaph
- Page 178 and 179: Other Anaphylactoid reactions/Anaph
- Page 180 and 181: Other Anaphylactoid reactions/Anaph
- Page 182 and 183: Candidiasis (
- Page 184 and 185: Herpes zoster (
- Page 186 and 187: Hypersensitivity Injection-site pai
- Page 188 and 189: Other Abdominal pain (25%) Anaphyla
- Page 190 and 191: CHLORAMBUCIL Trade names: Chloramin
- Page 192 and 193: (1992): Ramselaar CG+, Br J Urol 70
- Page 194 and 195: (1997): Selvaag E, Ann Trop Pediatr
- Page 196 and 197: (1989): Rosen C, Semin Dermatol 8,
- Page 198 and 199: CHOLESTYRAMINE Trade names: Chol-Le
- Page 200 and 201: CIMETIDINE Trade names: Apo-Cimetid
- Page 202 and 203: (2000): Sharobeem KM+, J Cardiovasc
- Page 204 and 205: (1997): Carrasco JM+, Ann Pharmacot
- Page 206 and 207: CITALOPRAM Synonym: nitalapram Trad
- Page 208 and 209: CLEMASTINE Trade names: Aller-Eze;
- Page 212 and 213: CLOMIPRAMINE Trade names: Anafranil
- Page 214 and 215: CLOPIDOGREL Trade name: Plavix (Bri
- Page 216 and 217: Eczema (
- Page 218 and 219: (1997): Thaler D, Monona, WI (from
- Page 220 and 221: COCOA Scientific names: Theobroma c
- Page 222 and 223: COLESEVELAM Trade name: Welchol (Sa
- Page 224 and 225: CORDYCEPS Scientific name: Cordycep
- Page 226 and 227: CYCLAMATE Trade name: Sucaryl (Abbo
- Page 228 and 229: Inappropriate secretion of antidiur
- Page 230 and 231: (1996): Cox NH, Clin Exp Dermatol 2
- Page 232 and 233: (2007): Lim AK+, Intern Med J 37(1)
- Page 234 and 235: (1989): Kerker BJ+, Semin Dermatol
- Page 236 and 237: Pruritus (1-10%) Rash (sic) (1-10%)
- Page 238 and 239: (1988): Tham SN+, Singapore Med J 2
- Page 240 and 241: DASATINIB Synonym: BMS354825 Trade
- Page 242 and 243: Other Anaphylactoid reactions/Anaph
- Page 244 and 245: (1980): Miescher PA+, Clin Haematol
- Page 246 and 247: (1985): Job JC+, Arch Fr Pediatr 42
- Page 248 and 249: DEXTROMETHORPHAN Trade names: Balmi
- Page 250 and 251: Erythema nodosum (
- Page 252 and 253: Mucosal Oral ulceration Hair Hair -
- Page 254 and 255: (1987): Masden JJ+, Curr Ther Res 4
- Page 256 and 257: (1998): Knowles S+, JAmAcadDermatol
- Page 258 and 259: Epiphora Other Abdominal pain Fever
136 CLOFAZIMINE<br />
Mucosal<br />
Cheilitis (c<strong>and</strong>idal) (
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